Homogeneous boron targeting of heterogeneous tumors for boron neutron capture therapy (BNCT): Chemical analyses in the hamster cheek pouch oral cancer model

Archives of Oral Biology

Volumn 51, Issue 10, 2006, Pages 922-929

  Heber, Elisa M ^a   Trivillin, Verónica A ^a   Nigg, David W ^b   Itoiz, Maria E ^a,c   Gonzalez, Beatriz N ^c   Rebagliati, Raúl J ^a   Batistoni, Daniel ^a   Kreimann, Erica L ^a   Schwint, Amanda E ^a  

^a DEPARTAMENTO DE FÍSICA   (Argentina)

^b IDAHO NATIONAL LABORATORY   (United States)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

BNCT; Boron targeting; Hamster cheek pouch; Oral cancer

Indexed keywords

4 DIHYDROXYBORYLPHENYLALANINE; 4-DIHYDROXYBORYLPHENYLALANINE; 7,12 DIMETHYLBENZ[A]ANTHRACENE; BORANE DERIVATIVE; BORON DERIVATIVE; DRUG DERIVATIVE; PHENYLALANINE;

ANIMAL; ARTICLE; CHEEK; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; HAMSTER; METABOLISM; METHODOLOGY; MOUTH MUCOSA; MOUTH TUMOR; NEUTRON CAPTURE THERAPY; PRECANCER; SYRIAN HAMSTER;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; BOROHYDRIDES; BORON COMPOUNDS; BORON NEUTRON CAPTURE THERAPY; CHEEK; CRICETINAE; DISEASE MODELS, ANIMAL; MESOCRICETUS; MOUTH MUCOSA; MOUTH NEOPLASMS; PHENYLALANINE; PRECANCEROUS CONDITIONS;

CRICETINAE;

EID: 33748608259     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archoralbio.2006.03.015     Document Type: Article

References (30)

1. Gabel D., Fairchild R.G., and Larsson B. The relative biological effectiveness in V79 Chinese hamster cells of the neutron capture reaction in boron and nitrogen. Radiat Res 98 (1984) 307-316
2. Coderre J., Glass J.D., Fairchild R.G., Micca P.L., Fand I., and Joel D.D. Selective delivery of boron by the melanin precursor analogue p-boronophenylalanine to tumors other than melanoma. Cancer Res 50 (1990) 138-141
3. Coderre J.A., and Morris G.M. The radiation biology of boron neutron capture therapy. Radiat Res 151 (1999) 1-18
4. Barth R.F., Coderre J.A., Vicente M.G.H., and Blue T.E. Boron neutron capture therapy of cancer: current status and future prospects. Clin Cancer Res 11 (2005) 3987-4002
5. Barth R.F. Rat brain tumor models in experimental neuro-oncology: the 9L, C6, T9, F98, RG2 (D74), RT-2, and CNS-1 gliomas. J Neuro-Oncol 36 (1998) 91-102
6. Kreimann E.L., Itoiz M.E., Dagrosa A., Garavaglia R., Farías S., Batistoni D., et al. The hamster cheek pouch as a model of oral cancer for boron neutron capture therapy studies: selective delivery of boron by boronophenylalanine. Cancer Res 61 (2001) 8775-8781
7. Salley J.J. Experimental carcinogenesis in the cheek pouch of the Syrian hamster. J Dent Res 33 (1954) 253-262
8. Kastenbauer E., and Wollenberg B. In search of new treatment methods for head-neck carcinoma. Laryngol Rhinol Otol 78 (1999) 31-35
9. Morris L. Factors influencing experimental carcinogenesis in the hamster cheek pouch. J Dent Res 40 (1961) 3-15
10. Cahan W.G. Multiple primary cancers of the lung, esophagus and other sites. Cancer (Phila) 40 (1977) 1954-1960
11. Dhooge J., De-Vos M., and Van-Cauwenberge P.B. Multiple primary malignant tumors in patients with head and neck cancer: results of a prospective study and future perspectives. Laryngoscope 108 (1998) 250-256
12. Smith D., and Haffty B.G. Molecular markers as prognostic factors for local recurrence and radioresistance in head and neck squamous cell carcinoma. Radiat Oncol Investig 7 (1999) 125-144
13. Kreimann E.L., Itoiz M.E., Longhino J., Blaumann H., Calzetta O., and Schwint A.E. Boron Neutron Capture Therapy for the treatment of oral cancer in the hamster cheek pouch model. Cancer Res (Adv Brief) 61 (2001) 8638-8642
14. Kreimann E.L., Miura M., Itoiz M.E., Heber E., Garavaglia R.N., Batistoni D., et al. Biodistribution of a carborane-containing porphyrin as a targeting agent for Boron Neutron Capture Therapy of oral cancer in the hamster cheek pouch. Arch Oral Biol 48 (2003) 223-232
15. Wittig A., Sauerwein W.A., and Coderre J.A. Mechanisms of transport of p-borono-phenylalanine through the cell membrane in vitro. Radiat Res 153 (2000) 173-180
16. Coderre J.A., Chanana A.D., Joel D.D., Elowitz E.H., Micca P.L., Nawrocky M.M., et al. Biodistribution of boronophenylalanine in patients with glioblastoma multiforme: boron concentration correlates with tumor cellularity. Radiat Res 149 (1998) 163-170
17. Patel H., and Sedgwick E.M. BPA and BSH accumulation in experimental tumors. Proceedings of the ninth international symposium on neutron capture therapy for cancer abstracts (2000) 59-60
18. Smith D.R., Chandra S., Barth R.F., Yang W., Joel D.D., and Coderre J.A. Quantitative imaging and microlocalization of Boron-10 in brain tumors and infiltrating cells by SIMS ion microscopy: relevance to neutron capture therapy. Cancer Res 61 (2001) 8179-8187
19. Ono K., Masunaga S., Suzuki M., Kinashi Y., Takagaki M., and Akaboshi M. The combined effect of boronophenylalanine and borocaptate in boron neutron capture therapy for SCCVII tumors in mice. Int J Radiat Oncol Biol Phys 43 (1999) 431-436
20. 10) compound for boron neutron capture therapy (BNCT) in an experimental model of oral cancer in the hamster cheek pouch. Arch Oral Biol 49 (2004) 313-324
21. Trivillin V.A., Heber E.M., Itoiz M.E., Nigg D., Calzetta O., Blaumann H., et al. Radiobiology of BNCT mediated by GB-10 and GB-10 + BPA in experimental oral cancer. Appl Radiat and Isotopes 61 (2004) 939-945
22. Trivillin VA, Heber EM, Nigg DW, Itoiz ME, Calzetta O, Blaumann H, Longhino J, Schwint AE. Therapeutic success of Boron Neutron Capture Therapy (BNCT) mediated by a chemically non-selective boron agent in an experimental model of oral cancer: A new paradigm in BNCT radiobiology. Radiat Res, in press.
23. Shklar G., Eisenberg E., and Flynn E. Immunoenhancing agents and experimental leukoplakia and carcinoma of the buccal pouch. Prog Exp Tumor Res 24 (1979) 269-282
24. LaHann T.R., Lu D.R., Daniell G., Kraft S.L., Gavin P.R., and Bauer W.F. Bioavailability of intravenous formulations of p-boronophenylalanine in dog and rat. In: Soloway A., Barth R., and Carpenter D. (Eds). Advances in Neutron Capture Therapy (1993), Plenum Press, New York 585-589
25. 10boron to oral squamous cell carcinoma using boronophenylalanine and borocaptate sodium for boron neutron capture therapy. Oral Oncol 40 (2004) 474-482
26. Fu K.K., Cooper J.S., Marcial V.A., Laramore G.E., Pajak T.F., Jacobs J., et al. Evolution of the radiation therapy oncology group clinical trials for head and neck cancer. Int J Radiat Oncol Biol Phys 35 (1996) 425-438
27. 10B-neutron capture therapy: enhancement of tumor dose via beam filtration and dose rate, and the effects of these parameters on minimum boron content: a theoretical evaluation. Int J Radiat Oncol Biol Phys 11 (1985) 831-840
28. Kato I., Ono K., Sakurai Y., Ohmae M., Maruhashi A., Imahori Y., et al. Effectiveness of BNCT for recurrent head and neck malignancies. Appl Radiat Isotopes 61 (2004) 1069-1073
29. Slaughter P., Southwick H.W., and Smejtal W. "Field cancerization" in oral stratified squamous epithelium: clinical implications of multicentric origin. Cancer (Phila) 6 (1953) 963-968
30. Chen B., Pogue B.W., Hoopes P.J., and Hasan T. Combining vascular and cellular targeting regimens enhances the efficacy of photodynamic therapy. Int J Radiat Oncol Biol Phys 61 (2005) 1216-1226