SCOPUS 정보 검색 플랫폼

Volumn 34, Issue 13-14, 1995, Pages 1483-1485

Burial of Hydrocarbon Causes Cooperative Enhancement of Electrostatic Binding

Author keywords

electrostatic binding; hydrophobic effect; molecular recognition; peptides

Indexed keywords

EID: 33748598167 PISSN: 05700833 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.199514831 Document Type: Article

Times cited : (27)

References (26)

5
- 0003996178
- 2nd ed., New York
- (1985) Enzyme Structure and Function , pp. Freeman
- Fersht, A.R.¹

9
- 0017702985
- Use of solvent cavity area and number of packed solvent molecules around a solute in regard to hydrocarbon solubilities and hydrophobic interactions
- (1977) Proceedings of the National Academy of Sciences , vol.74 , pp. 4144
- Herman, R.B.¹

14
- 0000005481
- Glycopeptide antibiotics have been shown to dimerize in aqueous solution
- (1989) J. Am. Chem. Soc. , vol.111 , pp. 2475
- Waltho, J.P.¹ Williams, D.H.²

16
- 84989531329
- 4573. This dimerization has been proposed to play an important role in mediating biological activity
- J. Am. Chem. Soc. , vol.116 , pp. 1994
- Mackay, J.P.¹ Gerhard, U.² Beauregard, D.A.³ Maplestone, R.A.⁴ Williams, D.H.⁵

17
- 0027936628
- dim is roughly a factor of 100 greater in the presence of ligands
- (1994) J. Am. Chem. Soc. , vol.116 , pp. 4581
- Mackay, J.P.¹ Gerhard, U.² Beauregard, D.A.³ Westwell, M.S.⁴ Searle, M.S.⁵ Williams, D.H.⁶

18
- 84989529373
- 2O solution using a 1–1 binomial solvent suppression sequence; exchangeable protons were assigned in all cases using 2D NOE experiments.

19
- 84989532238
- Cell wall analogues are bound within a shallow surface cleft on the antibiotic such that the deletion of methyl groups (Ala → Gly) results in exposure of the previously buried hydrocarbon of the antibiotic to solvent, rather than creating a vacant cavity.

22
- 0028275161
- J. Chem. Soc. Chem. Commun.
- (1994) , pp. 1519
- Groves, P.¹ Searle, M.S.² Westwell, M.S.³ Williams, D.H.⁴

24
- 84989523071
- It is of course also true that the peptide ligands containing one or more methyl groups will be less flexible than those containing only Gly residues. However, the term “burial of hydrocarbon” must include changes in flexibility in the bound state as well as the classical hydrophobic effect since the variables are inseparable.

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.