Base excision repair of both uracil and oxidatively damaged bases contribute to thymidine deprivation-induced radiosensitization

International Journal of Radiation Oncology Biology Physics

Volumn 65, Issue 5, 2006, Pages 1544-1552

  Allen, Bryan G ^a   Johnson, Monika ^b   Marsh, Anne E ^b   Dornfeld, Kenneth J ^b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA HEALTH CARE   (United States)

Author keywords

Base excision repair; Radiosensitization; Thymidine deprivation; Yeast

Indexed keywords

CELL CULTURE; DNA; DRUG PRODUCTS; IONIZING RADIATION; MUTAGENESIS; NITROGEN COMPOUNDS; ORGANIC COMPOUNDS; RADIATION EFFECTS; TOXICITY; YEAST;

BASE EXCISION REPAIR (BER); CYTOTOXICITY; RADIOSENSITIZATION; THYMIDINE DEPRIVATION;

GENETIC ENGINEERING;

AMINOPTERIN; FLUOROPYRIMIDINE; METHOXYAMINE; SULFANILAMIDE; THYMIDINE; URACIL; APN1 PROTEIN, S CEREVISIAE; DEOXYRIBONUCLEASE; FOLIC ACID ANTAGONIST; HYDROXYLAMINE; PYRIMIDINE NUCLEOTIDE; RAD52 PROTEIN; SACCHAROMYCES CEREVISIAE PROTEIN; SULFANILAMIDE DERIVATIVE; THYMIDINE 5'-TRIPHOSPHATE; THYMIDINE TRIPHOSPHATE; URACIL DNA GLYCOSIDASE;

ARTICLE; CELL VIABILITY; CLONOGENIC ASSAY; CONTROLLED STUDY; DNA RECOMBINATION; DNA REPAIR; EXCISION REPAIR; FUNGAL STRAIN; FUNGUS MUTANT; GENE DELETION; GENE LOCUS; NONHUMAN; OXIDATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIOSENSITIZATION; SACCHAROMYCES CEREVISIAE; BACTERIAL COUNT; DNA DAMAGE; DRUG EFFECT; GENETICS; METABOLISM; MUTATION; PHYSIOLOGY; RADIATION DOSE;

AMINOPTERIN; COLONY COUNT, MICROBIAL; DNA DAMAGE; DNA REPAIR; ENDODEOXYRIBONUCLEASES; FOLIC ACID ANTAGONISTS; HYDROXYLAMINES; MUTATION; RAD52 DNA REPAIR AND RECOMBINATION PROTEIN; RADIATION TOLERANCE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SULFANILAMIDES; THYMIDINE; THYMINE NUCLEOTIDES; URACIL; URACIL-DNA GLYCOSIDASE;

EID: 33748573979     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2006.03.051     Document Type: Article

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