Lens fluorescence in relation to glucose tolerance and genetic predisposition to type 2 diabetes mellitus in a population-based study

Current Eye Research

Volumn 31, Issue 9, 2006, Pages 733-738

  Theil, Pernille Koefoed ^a   Kessel, Line ^a   Hansen, Torben ^b   Lund Andersen, Henrik ^a   Pedersen, Oluf ^b   Larsen, Michael ^a,c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b STENO DIABETES CENTER   (Denmark)

^c GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Glucose metabolism; Lens fluorescence; Screening; Type 2 diabetes mellitus

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DISEASE DURATION; FAMILY HISTORY; FLUORESCENCE; FLUOROMETRY; GENETIC PREDISPOSITION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HUMAN; IMPAIRED GLUCOSE TOLERANCE; LENS; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL;

ADULT; AGED; AGED, 80 AND OVER; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; FEMALE; FLUORESCENCE; FLUOROPHOTOMETRY; GENETIC PREDISPOSITION TO DISEASE; GLUCOSE TOLERANCE TEST; GLYCEMIC INDEX; HUMANS; LENS, CRYSTALLINE; MALE; MIDDLE AGED;

EID: 33748562131     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.1080/02713680600850971     Document Type: Article

References (13)

1. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabetes Med. 1998;15:539-553.
2. Mooy JM, Grootenhuis PA, de Vries H, et al. Prevalence and determinants of glucose intolerance in a Dutch Caucasian population. The Hoorn Study. Diabetes Care. 1995;18:1270-1273.
3. Harris MI. Undiagnosed NIDDM: Clinical and public health issues. Diabetes Care. 1993;16:642-652.
4. Harris MI, Klein R, Welborn TA, Knuiman MW. Onset of NIDDM occurs at least 4-7 yr before clinical diagnosis. Diabetes Care. 1992;15:815-819.
5. UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ. 1998;317:703-713.
6. UK Prospective Diabetes Study (UKPDS) Group. Intensive bloodglucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998;352:837-853.
7. Koefoed Theil P, Hansen T, Larsen M, et al. Lens autofluorescence is increased in newly diagnosed patients with NIDDM. Diabetologia. 1996;39(12):1524-1527.
8. Bleeker JC, Van Best JA, Vrij L, et al. Autofluorescence of the lens in diabetic and healthy subjects by fluorophotometry. Invest Ophthalmol Vis Sci. 1986;27:791-794.
9. Larsen M, Kjer B, Bendtson I, et al. Lens fluorescence in relation to metabolic control of insulin-dependent diabetes mellitus. Arch Ophthalmol. 1989;107:59-62.
10. Clausen JO, Borch-Johnsen K, Ibsen H, et al. Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and lifestyle factors. J Clin Invest. 1996;98:1195-1209.
11. Urhammer SA, Hansen T, Ekstrom CT, et al. The Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene contributes to the interindividual variation in serum C-peptide response during an oral glucose tolerance test: Evidence from studies of 231 glucose-tolerant first-degree relatives of type 2 diabetic probands. J Clin Endocrinol Metab. 1998;83:4506-4509.
12. Urhammer SA, Moller AM, Nyholm B, et al. The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1alpha gene on estimates of the pancreatic beta-cell function in Caucasian glucose-tolerant first-degree relatives of type 2 diabetic patients. J Clin Endocrinol Metab. 1998;83:3992-3995.
13. Kessel L, Hougaard JL, Sander B, et al. Lens ageing as an indicator of tissue damage associated with smoking and nonenzymatic glycation-A twin study. Diabetologia. 2002;45:1457-1462.