Bacterial profile and burden of periodontal infection in subjects with a diagnosis of acute coronary syndrome

Journal of Periodontology

Volumn 77, Issue 7, 2006, Pages 1110-1119

  Renvert, Stefan ^a   Pettersson, Thomas ^b   Ohlsson, Ola ^a,b   Persson, G Rutger ^c,d  

^a KRISTIANSTAD UNIVERSITY   (Sweden)

^b CENTRAL HOSPITAL   (Sweden)

^c UNIVERSITY OF BERN   (Switzerland)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Infection; Myocardial infarction; Periodontitis; Porphyromonas gingivalis; Risk; Streptococci

Indexed keywords

BACTERIAL DNA; C REACTIVE PROTEIN; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN;

ACUTE CORONARY SYNDROME; ADULT; AGED; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM IDENTIFICATION; CONTROLLED STUDY; DNA DNA HYBRIDIZATION; FEMALE; HUMAN; INFECTION RISK; LEUKOCYTE COUNT; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; RISK ASSESSMENT; RISK FACTOR; SPECIES DIFFERENCE; STREPTOCOCCUS INTERMEDIUS; STREPTOCOCCUS SANGUINIS; TANNERELLA FORSYTHENSIS; TREPONEMA DENTICOLA; BACTEROIDES; BLOOD; CASE CONTROL STUDY; CHRONIC DISEASE; CORONARY ARTERY DISEASE; MICROBIOLOGY; MIDDLE AGED; NONPARAMETRIC TEST; NUCLEIC ACID HYBRIDIZATION; PATHOGENICITY; STATISTICAL MODEL; STREPTOCOCCUS ANGINOSUS; SYNDROME;

BACTEROIDES; CASE-CONTROL STUDIES; CHRONIC DISEASE; CORONARY DISEASE; FEMALE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; NUCLEIC ACID HYBRIDIZATION; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; RISK FACTORS; STATISTICS, NONPARAMETRIC; STREPTOCOCCUS ANGINOSUS; STREPTOCOCCUS INTERMEDIUS; STREPTOCOCCUS SANGUIS; SYNDROME; TREPONEMA DENTICOLA;

EID: 33748555206     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2006.050336     Document Type: Article

References (43)

1. Persson GR, Ohlsson O, Pettersson T, Renvert S. Chronic periodontitis, a significant predictor of acute myocardial infarction. Eur Heart J 2003;24:2108-2115.
2. Cueto A, Mesa F, Bravo M, Ocana-Riola R. Periodontitis as risk factor for acute myocardial infarction. A case control study of Spanish adults. J Periodontal Res 2005;40:36-42.
3. Beck JD, Offenbacher S, Williams R, Gibbs P, Garcia R. Periodontitis: A risk factor for coronary heart disease? Ann Periodontol 1998;3:127-141.
4. Adam E, Melnick JL, DeBakey ME. Cytomegalovirus infection and artherosclerosis. Cent Eur J Public Health 1997;5:99-106.
5. Cheng JW, Rivera NG. Infection and atherosclerosis - Focus on cytomegalovirus and Chlamydia pneumoniae. Ann Pharmacother 1998;32:1310-1316.
6. Coombes BK, Mahony JB. Chlamydia pneumoniae infection of human endothelial cells induces proliferation of smooth muscle cells via an endothelial cell-derived soluble factor(s). Infect Immun 1999;67:2909-2915.
7. Danesh J, Youngman L, Clark S, Parish S, Peto R, Collins R. Helicobacter pylori infection and early onset myocardial infarction: Case-control and sibling pairs study. BMJ 1999;319:1157-1162.
8. Desvarieux M, Demmer RT, Rundek T, et al. Periodontal microbiota and carotid intima-media thickness: The Oral Infections and Vascular Disease Epidemiology Study (INVEST). Circulation 2005;111:576-582.
9. Chiu B. Multiple infections in carotid atherosclerotic plaques. Am Heart J 1999;138:S534-S536.
10. Pussinen PJ, Alfthan G, Tuomilehto J, Asikainen S, Jousilahti P. High serum antibody levels to Porphyromonas gingivalis predict myocardial infarction. Eur J Cardiovasc Prev Rehabil 2004;11:408-411.
11. Imamura T, Banbula A, Pereira PJ, Travis J, Potempa J. Activation of human prothrombin by arginine-specific cysteine proteinases (Gingipains R) from Porphyromonas gingivalis. J Biol Chem 2001;276:18984-18991.
12. Lourbakos A, Yuan YP, Jenkins AL, et al. Activation of protease-activated receptors by gingipains from Porphyromonas gingivalis leads to platelet aggregation: A new trait in microbial pathogenicity. Blood 2001;97: 3790-3797.
13. Shi Y, Tokunaga O. Chlamydia pneumoniae (C. pneumoniae) infection upregulates atherosclerosis-related gene expression in human umbilical vein endothelial cells (HUVECs). Atherosclerosis 2004;177:245-253.
14. Haralambieva I, Iankov I, Petrov D, Ivanova R, Kamarinchev B, Mitov I. Cross-reaction between the genus-specific lipopolysaccharide antigen of Chlamydia spp. and the lipopolysaccharides of Porphyromonas gingivalis, Escherichia coli O119 and Salmonella newington: Implications for diagnosis. Diagn Microbiol Infect Dis 2001;41:99-106.
15. Choi JI, Chung SW, Kang HS, et al. Epitope mapping of Porphyromonas gingivalis heat-shock protein and human heat-shock protein in human atherosclerosis. J Dent Res 2004;83:936-940.
16. Yamazaki K, Ohsawa Y, Itoh H, et al. T-cell clonality to Porphyromonas gingivalis and human heat shock protein 60s in patients with atherosclerosis and periodontitis. Oral Microbiol Immunol 2004;19:160-167.
17. Socransky SS, Haffajee AD. Dental biofilms: Difficult therapeutic targets. Periodontol 2000 2002;28: 12-55.
18. Socransky SS, Haffajee AD, Smith C, Martin L, Haffajee JA, Goodson JM. Use of checkerboard DNA-DNA hybridization to study complex microbial ecosystems. Oral Microbiol Immunol 2004;19:352-362.
19. Jeppesen J, Hein HO, Suadicani P, Gyntelberg F. Triglyceride concentration and ischemic heart disease: An eight-year follow-up in the Copenhagen male study. Circulation 1998;97:1029-1036.
20. Katsoulis J, Heitz-Mayfield LJ, Weibel M, Hirschi R, Lang NP, Persson GR. Impact of sample storage on detection of periodontal bacteria. Oral Microbiol Immunol 2005;20:128-130.
21. Renvert S, Persson GR. Patient-based assessments of clinical periodontal conditions in relation to alveolar bone loss. J Clin Periodontol 2004;31:208-213.
22. Brodala N, Merricks EP, Bellinger DA, et al. Porphyromonas gingivalis bacteremia induces coronary and aortic atherosclerosis in normocholesterolemic and hypercholesterolemic pigs. Arterioscler Thromb Vasc Biol 2005;25:1446-1451.
23. Takai S, Kuriyama T, Yanagisawa M, Nakagawa K, Karasawa T. Incidence and bacteriology of bacteremia associated with various oral and maxillofacial surgical procedures. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005;99:292-298.
24. Ide M, Jagdev D, Coward PY, Crook M, Barclay GR, Wilson RF. The short-term effects of treatment of chronic periodontitis on circulating levels of endotoxin, C-reactive protein, tumor necrosis factor-alpha, and interieukin-6. J Periodontol 2004;75:420-428.
25. Allen BL, Katz B, Hook M. Streptococcus anginosus adheres to vascular endothelium basement membrane and purified extracellular matrix proteins. Microb Pathog 2002;32:191-204.
26. Inoue K, Kobayashi Y, Hanamura H, Toyokawa S. Association of periodontitis with increased white blood cell count and blood pressure. Blood Press 2005;14:53-58.
27. Mikx FH, Keulers RA. Hemagglutination activity of Treponema denticola grown in serum-free medium in continuous culture. Infect Immun 1992;60:1761-1766.
28. Sabet M, Lee SW, Nauman RK, Sims T, Um HS. The surface (S-) layer is a virulence factor of Bacteroides forsythus. Microbiology 2003;149:3617-3627.
29. Yamaguchi T, Taketoshi M, Eifuku-Koreeda H, Yakushiji T, Inoue M. Haemagglutinating activities of oral strains of Streptococcus milleri group. Microbios 1993;75:249-259.
30. Cecchi E, Forno D, Imazio M, et al. New trends in the epidemiological and clinical features of infective endocarditis: Results of a multicenter prospective study. Ital Heart J 2004;5:249-256.
31. Kitada K, Inoue M, Kitano M. Experimental endocarditis induction and platelet aggregation by Streptococcus anginosus, Streptococcus constellatus and Streptococcus intermedius. FEMS Immunol Med Microbiol 1997; 19:25-32.
32. Woo PC, Tse H, Chan KM, et al. "Streptococcus milleri" endocarditis caused by Streptococcus anginosus. Diagn Microbiol Infect Dis 2004;48:81-88.
33. Christan C, Dietrich T, Hagewald S, Kage A, Bernimoulin JP. White blood cell count in generalized aggressive periodontitis after non-surgical therapy. J Clin Periodontol 2002;29:201-206.
34. Cohen DJ, Malave D, Ghidoni JJ, et al. Role of oral bacterial flora in calcific aortic stenosis: An animal model. Ann Thorac Surg 2004;77:537-543.
35. Kerrigan SW, Douglas I, Wray A, et al. A role for glycoprotein Ib in Streptococcus sanguis-induced platelet aggregation. Blood 2002;100:509-516.
36. Gong K, Wen DY, Ouyang T, Rao AT, Herzberg MC. Platelet receptors for the Streptococcus sanguis adhesin and aggregation-associated antigens are distinguished by anti-idiotypical monoclonal antibodies. Infect Immun 1995;63:3628-3633.
37. Meyer MW, Gong K, Herzberg MC. Streptococcus sanguis-induced platelet clotting in rabbits and hemodynamic and cardiopulmonary consequences. Infect Immun 1998;66:5906-5914.
38. Khader YS, Albashaireh ZS, Alomari MA. Periodontal diseases and the risk of coronary heart and cerebrovascular diseases: A meta-analysis. J Periodontol 2004; 75:1046-1053.
39. Janket SJ, Qvarnstrom M, Meurman JH, Baird AE, Nuutinen P, Jones JA. Asymptotic dental score and prevalent coronary heart disease. Circulation 2004; 109:1095-1100.
40. Dogan B, Buduneli E, Emingil G, et al. Characteristics of periodontal microflora in acute myocardial infarction. J Periodontol 2005;76:740-748.
41. Czerniuk MR, Gorska R, Filipiak KJ, Opolski G. Inflammatory response to acute coronary syndrome in patients with coexistent periodontal disease. J Periodontol 2004;75:1020-1026.
42. Smeeth L, Thomas SL, Hall AJ, Hubbard R, Farrington P, Vallance P. Risk of myocardial infarction and stroke after acute infection or vaccination. N Engl J Med 2004;351:2611-2618.
43. Noack B, Genco RJ, Trevisan M, Grossi S, Zambon JJ, De Nardin E. Periodontal infections contribute to elevated systemic C-reactive protein level. J Periodontol 2001;72:1221-1227.