Unfolding single RNA molecules: Bridging the gap between equilibrium and non-equilibrium statistical thermodynamics

Quarterly Reviews of Biophysics

Volumn 38, Issue 4, 2005, Pages 291-301

  Bustamante, Carlos ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HELICASE; RIBOZYME; RNA;

CELL STIMULATION; CONFERENCE PAPER; FORCE; IN VITRO STUDY; INFORMATION; INTRON; KINETICS; MEASUREMENT; MOLECULE; NONHUMAN; PRIORITY JOURNAL; THEORY; THERMODYNAMICS; THERMUS THERMOPHILUS; VALIDITY;

ANIMALS; BASE SEQUENCE; BIOPHYSICS; INTRONS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; RNA; RNA, CATALYTIC; RNA, PROTOZOAN; TETRAHYMENA THERMOPHILA; THERMODYNAMICS;

EID: 33748549353     PISSN: 00335835     EISSN: 14698994     Source Type: Journal    
DOI: 10.1017/S0033583506004239     Document Type: Conference Paper

References (11)

1. BUSTAMANTE, C., CHEMLA, Y. R., FORDE, N. R. & IZHAKY, D. (2004). Mechanical process in biochemistry. Annual Review of Biochemistry 73, 705-748.
2. BUSTAMANTE, C., FINZI, L., SEBRING, P. E. & SMITH, S. B. (1991). Manipulation of single DNA molecules and measurement of their elastic properties under an optical microscope. In Optical Methods for Ultrasensitive Detection and Analysis: Techniques and Applications. SPIE Proceedings Series, vol. 1435, pp. 179-187.
3. BUSTAMANTE, C., LIPHARDT, J. & RITORT, F. (2005). The non-equilibrium dynamics of small systems. Physics Today 58, 43-48.
4. EVANS, D. J. & SEARLES, D. J. (2002). The fluctuation theorem. Advances in Physics 51, 1529-1585.
5. GORE, J., RITORT, F. & BUSTAMANTE, C. (2003). Bias and error in estimates of equilibrium free-energy differences from nonequilibrium measurements. Proceedings of the National Academy of Sciences USA 100, 12564-12569.
6. JARZYNSKI, C. (1997). Non-equilibrium equality for free energy differences. Physical Review Letters 78, 2690-2693.
7. LIPHARDT, J., DUMONT, S., SMITH, S. B., TINOCO JR., I. & BUSTAMANTE, C. (2002). Equilibrium information from non-equilibrium measurements in an experimental test of Jarzynski's equality. Science 296, 1832-1835.
8. LIPHARDT, J., ONOA, B., SMITH, S. B., TINOCO JR., I. & BUSTAMANTE, C. (2001). Reversible unfolding of single RNA molecule by force. Science 292, 733-737.
9. ONOA, B., DUMONT S., LIPHARDT J., SMITH S. B., TINOCO JR., I. & BUSTAMANTE, C. (2003). Identifying the kinetic barriers to mechanical unfolding of the T. thermophila ribozyme. Science 299, 1892-1895.
10. SMITH, S. B., FINZI, L. & BUSTAMANTE, C. (1992). Direct mechanical measurements of the elasticity of single DNA molecules using magnetic bead. Science 258, 1122-1126.
11. TINOCO JR., I. & BUSTAMANTE, C. (1999). How RNA folds. Journal of Molecular Biology 293, 271-281.