Development of a Percutaneous Cerebrospinal Fluid Collection Technique in F-344 Rats and Evaluation of Cell Counts and Total Protein Concentrations

Toxicologic Pathology

Volumn 34, Issue 4, 2006, Pages 393-395

  Sharma, Alok K ^a,b   Schultze, Albert E ^b   Cooper, Dale M ^b   Reams, Rachel Y ^b   Jordan, William H ^b   Snyder, Paul W ^a  

^a PURDUE UNIVERSITY   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

cerebrospinal fluid; CSF; erythrocytes; F 344 rats; nucleated cells; total protein concentration

Indexed keywords

PROTEIN;

ANIMAL; ARTICLE; CELL COUNT; CEREBROSPINAL FLUID; CHEMISTRY; COMPARATIVE STUDY; CYTOLOGY; ERYTHROCYTE COUNT; EVALUATION; FISCHER 344 RAT; LABORATORY DIAGNOSIS; MALE; METHODOLOGY; RAT;

ANIMALS; CELL COUNT; CEREBROSPINAL FLUID; ERYTHROCYTE COUNT; EVALUATION STUDIES; MALE; PROTEINS; RATS; RATS, INBRED F344; SPECIMEN HANDLING;

EID: 33748539340     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230600798609     Document Type: Article

References (19)

1. Consiglio AR, Lucion AB Technique for collecting cerebrospinal fluid in the cisterna magna of non-anesthetized rats Brain Res Brain Res Protoc 2000 5 109-14
2. Curzon G, Hutson PH, Kantamaneni BD, Sahakian BJ, Sarna GS 3,4-Dihydroxyphenylethylamine and 5-hydroxytryptamine metabolism in the rat: acidic metabolites in cisternal cerebrospinal fluid before and after giving probenecid J Neurochem 1985 45 508-13
3. De La Riva CF, Yeo JA Repeated determination of cerebrospinal fluid amine metabolites by automated direct sampling from an implanted cannula in freely moving rats J Neurosci Methods 1985 14 233-40
4. Dingemanse J, Hutson PH, Langemeijer MW, Curzon G, Danhof M Application of serial sampling of cerebrospinal fluid in phar-macodynamic studies with a drug active in the CNS: heptabarbital concentrations at onset and offset of loss of righting reflex in rats Neuropharmacology 1988 27 467-74
5. Frankmann SP A technique for repeated sampling of CSF from the anesthetized rat Physiol Behav 1986 37 489-93
6. Gunther O, Herger M Method for chronic catheterization of the rat cisterna magna Biomed Biochim Acta 1984 43 1199 200
7. Halonen T, Pitkanen A, Partanen J, Hyttinen JM, Riekkinen PJ Amino acid levels in cerebrospinal fluid of rats after administration of pentylenetetrazol Comp Biochem Physiol C 1992 101 21-5
8. Jolkkonen J, Tuomisto L, van Wimersma Greidanus TB, Laara E, Riekkinen PJ Vasopressin levels in the cerebrospinal fluid in rats of different age and sex Neuroendocrinology 1986 44 163-7
9. Jones HC Cerebrospinal Fluid Research: A new platform for dissemination of research, opinions and reviews with a common theme Cerebrospinal Fluid Res 2004 1 1
10. Klockowski PM, Levy G Simultaneous determination of diazepam and its active metabolites in rat serum, brain and cerebrospinal fluid by high-performance liquid chromatography J Chromatogr 1987 422 334-9
11. Kornhuber ME, Kornhuber J, Cimniak U A method for repeated CSF sampling in the freely moving rat J Neurosci Methods 1986a 17 63-8
12. Kornhuber ME, Kornhuber J, Kornhuber AW, Hartmann GM Positive correlation between contamination by blood and amino acid levels in cerebrospinal fluid of the rat Neurosci Lett 1986b 69 212-5
13. Luxton RW, Patel P, Keir G, Thompson EJ A micro-method for measuring total protein in cerebrospinal fluid by using benzethonium chloride in microtiter plate wells Clin Chem 1989 35 1731-4
14. Pagano M, Gauvreau K Pearson's Correlation Coefficient Principles of Biostatistics 2000 Duxbury Thomson Learning 400 404
15. Sanvitto GL, Azambuja NA, Marques M A technique for collecting cerebrospinal fluid using an intraventricular cannula in rats Physiol Behav 1987 41 523-4
16. Sokomba EN, Patsalos PN, Lolin YI, Curzon G Concurrent monitoring of central carbamazepine and transmitter amine metabolism and motor activity in individual unrestrained rats using repetitive withdrawal of cerebrospinal fluid Neuropharmacology 1988 27 409-15
17. Takemoto Y An improved method for using cisternal cerebrospinal fluid in conscious rats for application in the measurement of catecholamines Jpn J Physiol 1991 41 665-9
18. Westergren I, Johansson BB Changes in physiological parameters of rat cerebrospinal fluid during chronic sampling: evaluation of two sampling methods Brain Res Bull 1991 27 283-6
19. Ylitalo P, Heikkinen ER, Myllyla VV Evaluation of sucessive collections of cisternal cerebrospinal fluid in rats, rabbits, and cats Exp Neurol 1976 50 330-6