Enantioselective reduction of ketones with "designer cells" at high substrate concentrations: Highly efficient access to functionalized optically active alcohols

Angewandte Chemie - International Edition

Volumn 45, Issue 34, 2006, Pages 5677-5681

  Gröger, Harald ^a   Chamouleau, Francoise ^a   Orologas, Nicolas ^a   Rollmann, Claudia ^a   Drauz, Karlheinz ^a   Hummel, Werner ^b   Weckbecker, Andrea ^b   May, Oliver ^a  

^a EVONIK INDUSTRIES AG   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Alcohols; Asymmetric catalysis; Cofactors; Enzyme catalysis; Reductions

Indexed keywords

ASYMMETRIC CATALYSIS; COFACTORS; ENANTIOSELECTIVITIES; ENZYME CATALYSIS;

ENZYME KINETICS; KETONES; REDUCTION; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

ALCOHOLS;

ALCOHOL DEHYDROGENASE; ALCOHOL DERIVATIVE; GLUCOSE DEHYDROGENASE; KETONE;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; GROWTH, DEVELOPMENT AND AGING; OXIDATION REDUCTION REACTION; STEREOISOMERISM; SYNTHESIS;

ALCOHOL DEHYDROGENASE; ALCOHOLS; CATALYSIS; ESCHERICHIA COLI; GLUCOSE 1-DEHYDROGENASE; KETONES; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 33748530708     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200503394     Document Type: Article

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