Cough frequency in children with mild asthma correlates with sputum neutrophil count

Thorax

Volumn 61, Issue 9, 2006, Pages 747-750

  Li, A M ^a   Tsang, T W T ^a   Chan, D F Y ^a   Lam, H S ^a   So, H K ^a   Sung, R Y T ^a   Fok, T F ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; NITRIC OXIDE;

ADOLESCENT; ADULT; ARTICLE; CLUSTER ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; COUGHING; DEMOGRAPHY; DISEASE CLASSIFICATION; DISEASE SEVERITY; EXPIRATORY RESERVE VOLUME; FEMALE; HUMAN; INFLAMMATION; LEUKOCYTE DIFFERENTIAL COUNT; MALE; MEDICAL ASSESSMENT; MEDICAL INSTRUMENTATION; MILD INTERMITTENT ASTHMA; MORBIDITY; NEUTROPHIL COUNT; PATIENT MONITORING; PRIORITY JOURNAL; SCHOOL CHILD; SPIROMETRY; SPUTUM ANALYSIS;

ASTHMA; BREATH TESTS; CHILD; COUGH; FEMALE; HUMANS; LEUKOCYTE COUNT; MALE; NEUTROPHILS; NITRIC OXIDE; PROSPECTIVE STUDIES; SPIROMETRY; SPUTUM;

EID: 33748527771     PISSN: 00406376     EISSN: None     Source Type: Journal    
DOI: 10.1136/thx.2005.050815     Document Type: Article

References (32)

1. Chang AB. State of the art: cough, cough receptors and asthma in children. Pediatr Pulmonol 1999;28:59-70.
2. Chang AB, Phelan PD, Robertson CF. Cough receptor sensitivity in children with acute and non-acute asthma. Thorax 1997;52:770-4.
3. Green R, Luyt D. Clinical characteristics of childhood asthmatics in Johannesburg. S Afr Med J 1997;87:878-82.
4. Brooke AM, Lambert PC, Burton PR, et al. Night cough in a population-based sample of children: characteristics, relation to symptoms and associations with measures of asthma severity. Eur Respir J 1996;9:65-71.
5. Hoskyns EW, Beardsmore CS, Simpson H. Chronic night cough and asthma severity in children with stable asthma. Eur J Pediatr 1995;154:320-5.
6. Li AM, Lex C, Zacharasiewicz A, et al. Cough frequency in children with stable asthma: correlation with lung function, exhaled nitric oxide, and sputum eosinophil count. Thorax 2003;58:974-8.
7. Archer LNJ, Simpson H. Night cough counts and diary card scores in asthma. Arch Dis Child 1985;60:473-4.
8. Falconer A, Oldman C, Helms P. Poor agreement between reported and recorded nocturnal cough in asthma. Pediatr Pulmonol 1993;15:209-11.
9. Brunekreef B, Groot B, Rijcken B, et al. Reproducibility of childhood respiratory symptom questions. Eur Respir J 1992;5:930-5.
10. Juniper EF, Guyatt GH, Dolovich J. Assessment of quality of life in adolescents with allergic rhinoconjunctivitis: development and testing of a questionnaire for clinical trials. J Allergy Clin Immunol 1994;93:413-23.
11. Thompson AH, Pratt C, Simpson H. Nocturnal cough in asthma. Arch Dis Child 1987;62:1001-4.
12. Munyard P, Busst C, Logan-Sinclair R, et al. A new device for ambulatory cough recording. Pediatr Pulmonol 1994;18:178-86.
13. Munyard P, Bush A. How much coughing is normal? Arch Dis Child 1996;74:531-4.
14. Hamutcu R, Francis J, Karakoc F, et al. Objective monitoring of cough in children with cystic fibrosis. Pediatr Pulmonol 2002;34:331-5.
15. Corrigan DL, Paton JY. Pilot study of objective cough monitoring in infants. Pediatr Pulmonol 2003;35:350-7.
16. Warner JO. Asthma: a follow up statement from an international paediatric asthma consensus group. Arch Dis Child 1992;67:240-8.
17. American Thoracic Society. Recommendation for standardized procedures for the on-line and off-line measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children - 1999. Am J Respir Crit Care Med 1999;160:2104-17.
18. Ip MS, Karlberg EM, Karlberg JP, et al. Lung function reference values in Chinese children and adolescents in Hong Kong. Am J Respir Crit Care Med 2000;162:424-9.
19. Smith CM, Anderson SD. Inhalational challenge using hypertonic saline in asthmatic subjects: a comparison with responses to hyperpnoea, metacholine and water. Eur Respir J 1990;3:144-51.
20. Fahy JV, Boushey HA, Lazarus SC, et al. Safety and reproducibility of sputum induction in asthmatic subjects in a multicenter study. Am J Respir Crit Care Med 2001;163:1470-5.
21. Rietveld S, Rijssenbeek-Nouwens LH. Diagnostics of spontaneous cough in childhood asthma: results of continuous tracheal sound recording in the homes of children. Chest 1998;113:50-4.
22. van den Toorn LM, Overbeek SE, de Jongste JC, et al. Airway inflammation is present during clinical remission of atopic asthma. Am J Respir Crit Care Med 2001;164:2107-13.
23. Cai Y, Carty K, Henry RL, et al. Persistence of sputum eosinophilia in children with controlled asthma when compared with healthy children. Eur Respir J 1998;11:848-53.
24. Chang AB, Harrhy VA, Simpson J, et al. Cough, air inflammation, and mild asthma exacerbation. Arch Dis Child 2002;86:270-5.
25. Norzila MZ, Fakes K, Henry RL, et al. Interleukin-8 secretion and neutrophil recruitment accompanies induced sputum eosinophil activation in children with acute asthma. Am J Respir Crit Care Med 2000;161:769-74.
26. Sur S, Crotty TB, Kephart GM, et al. Sudden-onset fatal asthma. A distinct entity with few eosinophils and relatively more neutrophils in the airway submucosa? Am Rev Respir Dis 1993;148:713-9.
27. Pizzkhini MM, Pizzichini E, Efthimiadis A, et al. Asthma and natural colds. Inflammatory indices in induced sputum: a feasibility study. Am J Respir Crit Care Med 1998;158:1178-84.
28. Douwes J, Gibson P, Pekkanen J, et al. Non-eosinophilic asthma: importance and possible mechanisms. Thorax 2002;57:643-8.
29. Yasui K, Kanda H, Iwanami T, et al. Increased serum concentration of urinary trypsin inhibitor with asthma exacerbation. Eur Respir J 2003;22:739-42.
30. Kamath AV, Pavord ID, Ruparelia PR, et al. Is the neutrophil the key effector cell in severe asthma? Thorax 2005;60:529-30.
31. Stevenson EC, Turner G, Heaney LG, et al. Bronchoalveolar lavage findings suggest two different forms of childhood asthma. Clin Exp Allergy 1997;27:1027-35.
32. Fitch PS, Brown V, Schock BC, et al. Chronic cough in children: bronchoalveolar lavage findings. Eur Respir J 2000;16:1109-14.