-
2
-
-
0036242654
-
Lennox-Gastaut syndrome
-
Crumrine PK. Lennox-Gastaut syndrome. J Child Neurol 2002 Jan; 17 Suppl. 1: S70-5
-
(2002)
J Child Neurol
, vol.17
, Issue.1 SUPPL.
-
-
Crumrine, P.K.1
-
3
-
-
0031783133
-
Treatment of Lennox-Gastaut syndrome: Current recommendations
-
Sep
-
Delanty N, French J. Treatment of Lennox-Gastaut syndrome: current recommendations. CNS Drugs 1998 Sep; 10: 181-8
-
(1998)
CNS Drugs
, vol.10
, pp. 181-188
-
-
Delanty, N.1
French, J.2
-
5
-
-
33748568362
-
-
The Epilepsy Foundation [online]
-
The Epilepsy Foundation [online]. Available from URL: http://www.epilepsyfoundation.org/answerplace/Medical/seizures/types/ partialSeizures/index.cfm [Accessed 2006 Jun 8]
-
-
-
-
7
-
-
0034023011
-
An assessment of rufinamide as an anti-epileptic in comparison with other drugs in clinical development
-
Apr
-
Jain KK. An assessment of rufinamide as an anti-epileptic in comparison with other drugs in clinical development. Expert Opin Investig Drugs 2000 Apr; 9 (4): 829-40
-
(2000)
Expert Opin Investig Drugs
, vol.9
, Issue.4
, pp. 829-840
-
-
Jain, K.K.1
-
8
-
-
33747038871
-
The influence of rufinamide on sodium currents and action potential firing in rodent neurons
-
abstract no. 3.062. Plus poster presented at the 59th Annual American Epilepsy Society Meeting; 2005 Dec 2-296. Plus poster presented at the 59th Annual American Epilepsy Society M6; Washington, DC
-
McLean MJ, Schmutz M, Pozza M, et al. The influence of rufinamide on sodium currents and action potential firing in rodent neurons [abstract no. 3.062]. Epilepsia 2005; 46 Suppl. 8: 296. Plus poster presented at the 59th Annual American Epilepsy Society Meeting; 2005 Dec 2-296. Plus poster presented at the 59th Annual American Epilepsy Society M6; Washington, DC
-
(2005)
Epilepsia
, vol.46
, Issue.8 SUPPL.
, pp. 296
-
-
McLean, M.J.1
Schmutz, M.2
Pozza, M.3
-
9
-
-
33747069013
-
The anticonvulsant profile and tolerability of rufinamide in mice and rats
-
abstract no. 3.088. Plus poster presented at the 59th Annual American Epilepsy Society Meeting; 2005 Dec 2-6; Washington, DC
-
White HS, Schmutz M, Pozza M, et al. The anticonvulsant profile and tolerability of rufinamide in mice and rats [abstract no. 3.088]. Epilepsia 2005; 46 Suppl. 8: 305-6. Plus poster presented at the 59th Annual American Epilepsy Society Meeting; 2005 Dec 2-6; Washington, DC
-
(2005)
Epilepsia
, vol.46
, Issue.8 SUPPL.
, pp. 305-306
-
-
White, H.S.1
Schmutz, M.2
Pozza, M.3
-
10
-
-
33749829255
-
-
The effect of rufinamide concentration on the QT interval in healthy subjects treated during 18 days with multiple ascending doses: a population PKPD analysis [abstract no. A785 plus poster]. June 16-7; Pamplona
-
Marchand M, Critchley D, Nagy C, et al. The effect of rufinamide concentration on the QT interval in healthy subjects treated during 18 days with multiple ascending doses: a population PKPD analysis [abstract no. A785 plus poster]. Annual Meeting of the Population Approach Group in Europe; 2005 June 16-7; Pamplona
-
(2005)
Annual Meeting of the Population Approach Group in Europe
-
-
Marchand, M.1
Critchley, D.2
Nagy, C.3
-
11
-
-
33748522220
-
Pharmacokinetic and pharmacodynamic parameters of adjunctive rufinamide in patients with Lennox-Gastaut syndrome
-
[abstract no. 2.351]. Plus poster presented at the 59th Annual American Epilepsy Society Meeting; 2005 Dec 2-209. Plus poster presented at the 59th Annual American Epilepsy Society M6; Washington, DC
-
Critchley D, Fuseau E, Perdomo C, et al. Pharmacokinetic and pharmacodynamic parameters of adjunctive rufinamide in patients with Lennox-Gastaut syndrome [abstract no. 2.351]. Epilepsia 2005; 46 Suppl. 8: 209. Plus poster presented at the 59th Annual American Epilepsy Society Meeting; 2005 Dec 2-209. Plus poster presented at the 59th Annual American Epilepsy Society M6; Washington, DC
-
(2005)
Epilepsia
, vol.46
, Issue.8 SUPPL.
, pp. 209
-
-
Critchley, D.1
Fuseau, E.2
Perdomo, C.3
-
12
-
-
1442306232
-
Drug-induced prolongation of the QT interval
-
Roden DM. Drug-induced prolongation of the QT interval. N Engl J Med 2004; 350 (10): 1013-22
-
(2004)
N Engl J Med
, vol.350
, Issue.10
, pp. 1013-1022
-
-
Roden, D.M.1
-
13
-
-
0000029301
-
Metabolism of the new anticonvulsive trial drug rufinamide (CGP 33101) in healthy male volunteers
-
abstract no. 6.60
-
Waldmeier F, Gschwind HP, Rouan MC, et al. Metabolism of the new anticonvulsive trial drug rufinamide (CGP 33101) in healthy male volunteers [abstract no. 6.60]. Epilepsia 1996; 37 Suppl. 5: 167
-
(1996)
Epilepsia
, vol.37
, Issue.5 SUPPL.
, pp. 167
-
-
Waldmeier, F.1
Gschwind, H.P.2
Rouan, M.C.3
-
14
-
-
0031959729
-
The influence of food on the disposition of the antiepileptic rufinamide in healthy volunteers
-
May
-
Cardot JM, Lecaillon JB, Czendlik C, et al. The influence of food on the disposition of the antiepileptic rufinamide in healthy volunteers. Biopharm Drug Dispos 1998 May; 19 (4): 259-62
-
(1998)
Biopharm Drug Dispos
, vol.19
, Issue.4
, pp. 259-262
-
-
Cardot, J.M.1
Lecaillon, J.B.2
Czendlik, C.3
-
15
-
-
33748532681
-
Rufinamide, a novel antiepileptic drug, does not alter the pharmacokinetics of a CYP1A2 substrate, olanzapine, in healthy adults
-
Kalbag JB, White-van Logtenberg M, Yeh CM, et al. Rufinamide, a novel antiepileptic drug, does not alter the pharmacokinetics of a CYP1A2 substrate, olanzapine, in healthy adults [abstract]. Epilepsia 2000; 41 Suppl.: 150
-
(2000)
Epilepsia
, vol.41
, pp. 150
-
-
Kalbag, J.B.1
White-van Logtenberg, M.2
Yeh, C.M.3
-
16
-
-
0006492632
-
Single-center, open-label, multiple-dose pharmacokinetic trial investigating the effect of rufinamide administration on Ortho-Novum 1/35 in healthy women
-
abstract no. 2.111
-
Svendsen KD, Choi L, Chen BL, et al. Single-center, open-label, multiple-dose pharmacokinetic trial investigating the effect of rufinamide administration on Ortho-Novum 1/35 in healthy women [abstract no. 2.111]. Epilepsia 1998; 39 Suppl. 6: 59
-
(1998)
Epilepsia
, vol.39
, Issue.6 SUPPL.
, pp. 59
-
-
Svendsen, K.D.1
Choi, L.2
Chen, B.L.3
-
17
-
-
0029566317
-
Intra- and inter-subject variabilities of CGP 33101 after replicate single oral doses of two 200-mg tablets and 400-mg suspension
-
Dec
-
Cheung WK, Kianifard F, Wong A, et al. Intra- and inter-subject variabilities of CGP 33101 after replicate single oral doses of two 200-mg tablets and 400-mg suspension. Pharm Res 1995 Dec; 12: 1878-82
-
(1995)
Pharm Res
, vol.12
, pp. 1878-1882
-
-
Cheung, W.K.1
Kianifard, F.2
Wong, A.3
-
18
-
-
33748542146
-
Population pharmacokinetic drug-drug interaction analyses of rufinamide studies in patients with epilepsy
-
abstract no. 2.356. Plus poster presented at the 59th Annual American Epilepsy Society Meeting; 2005 Dec 2-6; Washington, DC
-
Fuseau E, Critchley D, Perdomo C, et al. Population pharmacokinetic drug-drug interaction analyses of rufinamide studies in patients with epilepsy [abstract no. 2.356]. Epilepsia 2005; 46 Suppl. 8: 210-11. Plus poster presented at the 59th Annual American Epilepsy Society Meeting; 2005 Dec 2-6; Washington, DC
-
(2005)
Epilepsia
, vol.46
, Issue.8 SUPPL.
, pp. 210-211
-
-
Fuseau, E.1
Critchley, D.2
Perdomo, C.3
-
19
-
-
33748569315
-
Population pharmacokinetics and drug-drug interactions of rufinamide in a multicenter, double-blind, randomized, placebo-controlled, 5-arm parallel trial in patients with partial seizures on up to three concomitant antiepileptic drugs
-
Racine A, Rouan MC, Chang SW, et al. Population pharmacokinetics and drug-drug interactions of rufinamide in a multicenter, double-blind, randomized, placebo-controlled, 5-arm parallel trial in patients with partial seizures on up to three concomitant antiepileptic drugs [abstract]. Epilepsia 2000; 41 Suppl.: 149-50
-
(2000)
Epilepsia
, vol.41
, Issue.SUPPL.
, pp. 149-150
-
-
Racine, A.1
Rouan, M.C.2
Chang, S.W.3
-
21
-
-
33748527987
-
-
Data on file, Eisai Limited
-
Data on file, Eisai Limited
-
-
-
-
22
-
-
0006756605
-
A geriatric pharmacokinetic evaluation of rufinamide
-
abstract no. PIII-48. Feb
-
Chang SW, Yeh CM, Van Logtenberg M, et al. A geriatric pharmacokinetic evaluation of rufinamide [abstract no. PIII-48]. Clin Pharmacol Ther 2000 Feb; 67: 154
-
(2000)
Clin Pharmacol Ther
, vol.67
, pp. 154
-
-
Chang, S.W.1
Yeh, C.M.2
Van Logtenberg, M.3
-
23
-
-
0006756610
-
Evaluation of rufinamide (CGP 33101), a novel anticonvulsant, for potential drug interactions in vitro
-
abstract no. 1.96
-
Kapeghian JC, Madan A, Parkinson A, et al. Evaluation of rufinamide (CGP 33101), a novel anticonvulsant, for potential drug interactions in vitro [abstract no. 1.96]. Epilepsia 1996; 37 Suppl. 5: 26
-
(1996)
Epilepsia
, vol.37
, Issue.5 SUPPL.
, pp. 26
-
-
Kapeghian, J.C.1
Madan, A.2
Parkinson, A.3
-
24
-
-
33748525044
-
Efficacy and safety of rufinamide adjunctive therapy in patients with Lennox-Gastaut syndrome (LGS): A multicenter, randomized, double-blind, placebo-controlled, parallel trial
-
abstract no. LBS.001. Mar 22; Plus poster presented at the 57th Annual Meeting of the American Academy of Neurology; 2005 Apr 9-16; Miami Beach (FL)
-
Glauser TA, Kluger G, Sachdeo R, et al. Efficacy and safety of rufinamide adjunctive therapy in patients with Lennox-Gastaut syndrome (LGS): a multicenter, randomized, double-blind, placebo-controlled, parallel trial [abstract no. LBS.001]. Neurology 2005 Mar 22; 64 Suppl. 1: 1826. Plus poster presented at the 57th Annual Meeting of the American Academy of Neurology; 2005 Apr 9-16; Miami Beach (FL)
-
(2005)
Neurology
, vol.64
, Issue.1 SUPPL.
, pp. 1826
-
-
Glauser, T.A.1
Kluger, G.2
Sachdeo, R.3
-
25
-
-
33748541467
-
Open-label extension study of the efficacy and safety of rufinamide adjunctive therapy in patients with Lennox-Gastaut syndrome
-
abstract no. p1356. Plus poster presented at the 26th International Epilepsy Congress; 2005 Aug 28-Sep 1; Paris
-
Glauser T, Kluger G, Sachdeo R, et al. Open-label extension study of the efficacy and safety of rufinamide adjunctive therapy in patients with Lennox-Gastaut syndrome [abstract no. p1356]. Epilepsia 2005; 46 Suppl. 6: 408. Plus poster presented at the 26th International Epilepsy Congress; 2005 Aug 28-Sep 1; Paris
-
(2005)
Epilepsia
, vol.46
, Issue.6 SUPPL.
, pp. 408
-
-
Glauser, T.1
Kluger, G.2
Sachdeo, R.3
-
26
-
-
33748553536
-
Dose-range relationships of rufinamide in patients with inadequately controlled partial seizures
-
abstract no. 1.201. Oct; Plus poster presented at the 59th Annual American Epilepsy Society Meeting; 2005 Dec 2-6; Washington, DC
-
Elger C, Stefan H, Perdomo C, et al. Dose-range relationships of rufinamide in patients with inadequately controlled partial seizures [abstract no. 1.201]. Epilepsia 2005 Oct; 46 Suppl. 8: 83-4. Plus poster presented at the 59th Annual American Epilepsy Society Meeting; 2005 Dec 2-6; Washington, DC
-
(2005)
Epilepsia
, vol.46
, Issue.8 SUPPL.
, pp. 83-84
-
-
Elger, C.1
Stefan, H.2
Perdomo, C.3
-
27
-
-
33747138791
-
Efficacy and safety of rufinamide as adjunctive therapy in adult patients with inadequately controlled partial seizures
-
abstract no. 2.239. Oct; Plus poster presented at the 59th Annual American Epilepsy Society Meeting; 2005 Dec 2-171. Plus poster presented at the 59th Annual American Epilepsy Society M6; Washington, DC
-
Brodie MJ, Rosenfeld W, Vasquez B, et al. Efficacy and safety of rufinamide as adjunctive therapy in adult patients with inadequately controlled partial seizures [abstract no. 2.239]. Epilepsia 2005 Oct; 46 Suppl. 8: 171. Plus poster presented at the 59th Annual American Epilepsy Society Meeting; 2005 Dec 2-171. Plus poster presented at the 59th Annual American Epilepsy Society M6; Washington, DC
-
(2005)
Epilepsia
, vol.46
, Issue.8 SUPPL.
, pp. 171
-
-
Brodie, M.J.1
Rosenfeld, W.2
Vasquez, B.3
-
28
-
-
0035150482
-
Rufinamide: A double-blind, placebo-controlled proof of principle trial in patients with epilepsy
-
Feb
-
Palhagen S, Canger R, Henriksen O, et al. Rufinamide: a double-blind, placebo-controlled proof of principle trial in patients with epilepsy. Epilepsy Res 2001 Feb; 43 (2): 115-24
-
(2001)
Epilepsy Res
, vol.43
, Issue.2
, pp. 115-124
-
-
Palhagen, S.1
Canger, R.2
Henriksen, O.3
-
29
-
-
33748534339
-
-
Short-term and long-term safety of rufinamide in adult and adolescent patients with partial seizures [poster]. Dec 2-6; Washington, DC
-
Krauss GL, Perdomo CA, Arroyo S. Short-term and long-term safety of rufinamide in adult and adolescent patients with partial seizures [poster]. 59th Annual American Epilepsy Society Meeting; 2005 Dec 2-6; Washington, DC
-
(2005)
59th Annual American Epilepsy Society Meeting
-
-
Krauss, G.L.1
Perdomo, C.A.2
Arroyo, S.3
-
30
-
-
33746111455
-
The effect of the new antiepileptic drug rufinamide on cognitive functions
-
Aldenkamp AP, Alpherts WCJ. The effect of the new antiepileptic drug rufinamide on cognitive functions. Epilepsia 2006; 47 (7): 1153-9
-
(2006)
Epilepsia
, vol.47
, Issue.7
, pp. 1153-1159
-
-
Aldenkamp, A.P.1
Alpherts, W.C.J.2
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