Pathophysiological characteristics of the various forms of gastro-oesophageal reflux disease. Spectrum disease or distinct phenotypic presentations?

Digestive and Liver Disease

Volumn 38, Issue 9, 2006, Pages 643-648

  Frazzoni, M ^a   Manno, M ^a   De Micheli, E ^a   Savarino, V ^b  

^a Nuovo Ospedale S Agostino   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

Barrett's oesophagus; Gastro oesophageal reflux disease; Oesophageal pH monitoring

Indexed keywords

ADULT; AGED; ARTICLE; BARRETT ESOPHAGUS; CONTROLLED STUDY; DISEASE SEVERITY; ESOPHAGUS MANOMETRY; ESOPHAGUS PH; FEMALE; GASTROESOPHAGEAL REFLUX; HEARTBURN; HUMAN; LOWER ESOPHAGUS SPHINCTER PRESSURE; MAJOR CLINICAL STUDY; MALE; MONITORING; PATHOPHYSIOLOGY; PHENOTYPE; REFLUX ESOPHAGITIS; SYMPTOM; ULCERATIVE ESOPHAGITIS;

ADULT; AGE FACTORS; AGED; BARRETT ESOPHAGUS; CASE-CONTROL STUDIES; ENDOSCOPY, GASTROINTESTINAL; ESOPHAGEAL PH MONITORING; ESOPHAGITIS; FEMALE; GASTROESOPHAGEAL REFLUX; HEARTBURN; HERNIA, HIATAL; HUMANS; MALE; MANOMETRY; MIDDLE AGED; ULCER;

EID: 33748509949     PISSN: 15908658     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dld.2006.02.020     Document Type: Article

References (41)

1. DeVault K.R., and Castell D.O. Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease. Am J Gastroenterol 100 (2005) 190-200
2. Sonnenberg A. Review article: trials on reflux disease-the role of acid secretion and inhibition. Aliment Pharmacol Ther 20 Suppl. 5 (2004) 2-8
3. Fass R., and Ofman J.J. Gastroesophageal reflux disease-should we adopt a new conceptual framework?. Am J Gastroenterol 97 (2002) 1902-1909
4. Tack J., and Fass R. Review article: approaches to endoscopic-negative reflux disease: part of the GERD spectrum or a unique acid-related disorder?. Aliment Pharmacol Ther 19 Suppl. 1 (2004) 28-34
5. Kahrilas P.J., and Pandolfino J.E. Gastroesophageal reflux disease and its complications, including Barrett's metaplasia. In: Feldman M., Friedman L.S., and Sleisenger M.H. (Eds). Sleisenger & Fordtran gastrointestinal and liver disease. 7th ed. (2002), W.B. Saunders, Philadelphia 599-622
6. Sampliner R.E., and The Practice Parameters Committee of the American College of Gastroenterology. Practice guidelines on the diagnosis, surveillance, and therapy of Barrett's esophagus. Am J Gastroenterol 93 (1998) 1028-1032
7. Sharma P., Morales T.G., and Sampliner R.E. Short segment Barrett's esophagus-the need for standardization of the definition and of endoscopic criteria. Am J Gastroenterol 93 (1998) 1033-1036
8. Little A.G., DeMeester T.R., Kirchner P.T., O'Sullivan G.C., and Skinner D.B. Pathogenesis of esophagitis in patients with gastroesophageal reflux. Surgery 88 (1980) 101-107
9. Robertson D., Aldersley M., Shepherd H., and Smith C.L. Patterns of acid reflux in complicated oesophagitis. Gut 28 (1987) 1484-1488
10. Pujol A., Grande L., Ros E., and Pera C. Utility of inpatient 24-h intraesophageal pH monitoring in diagnosis of gastroesophageal reflux. Dig Dis Sci 33 (1988) 1134-1140
11. Rokkas T., and Sladen G.E. Ambulatory esophageal pH recording in gastroesophageal reflux: relevance to the development of esophagitis. Am J Gastroenterol 83 (1988) 629-632
12. Fiorucci S., Santucci L., Chiucchiu S., and Morelli A. Gastric acidity and gastroesophageal reflux patterns in patients with esophagitis. Gastroenterology 103 (1992) 855-861
13. Kasapidis P., Xynos E., Mantides A., Chrysos E., Demonakou M., Nikolopoulos M., et al. Differences in manometry and 24-h ambulatory pH-metry between patients with and without endoscopic or histological esophagitis in gastroesophageal reflux disease. Am J Gastroenterol 88 (1993) 1893-1899
14. Orr W.C., Allen M.L., and Robinson M. The pattern of nocturnal and diurnal esophageal acid exposure in the pathogenesis of erosive mucosal damage. Am J Gastroenterol 89 (1994) 509-512
15. Saraswat V.A., Dhiman R.K., Mishra A., and Naik S.R. Correlation of 24-h esophageal pH patterns with clinical features and endoscopy in gastroesophageal reflux disease. Dig Dis Sci 39 (1994) 199-205
16. Vaezi M.F., and Richter J.E. Role of acid and duodenogastroesophageal reflux in gastroesophageal reflux disease. Gastroenterology 111 (1996) 1192-1199
17. Hatlebakk J.G., and Berstad A. Endoscopic grading of reflux oesophagitis: what observations correlate with gastro-oesophageal reflux?. Scand J Gastroenterol 32 (1997) 760-765
18. Cadiot G., Bruhat A., Rigaud D., Coste T., Vuagnat A., Benyedder Y., et al. Multivariate analysis of pathophysiological factors in reflux oesophagitis. Gut 40 (1997) 167-174
19. Loughney M.A.J.T., Maydonovitch C.L., and Wong R.K.H. Esophageal manometry and ambulatory 24-h pH monitoring in patients with short and long segment Barrett's esophagus. Am J Gastroenterol 93 (1998) 916-919
20. Campos G.M., Peters J.H., DeMeester T.R., Oberg S., Crookes P.F., and Mason R.J. The pattern of esophageal acid exposure in gastroesophageal reflux disease influences the severity of the disease. Arch Surg 134 (1999) 882-887
21. Lundell L.R., Dent J., Bennett J.R., Blum A.L., Armstrong D., Galmiche J.P., et al. Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification. Gut 45 (1999) 172-180
22. Fass R., Hell R.W., Garewal H.S., Martinez P., Pulliam G., Wendel C., et al. Correlation of oesophageal acid exposure with Barrett's oesophagus length. Gut 48 (2001) 310-313
23. Avidan B., Sonnenberg A., Schnell T.G., and Sontag S.J. Hiatal hernia and acid reflux frequency predict presence and length of Barrett's esophagus. Dig Dis Sci 47 (2002) 256-264
24. Zentilin P., Conio M., Mele M.R., Mansi C., Pandolfo N., Dulbecco P., et al. Comparison of the main oesophageal pathophysiological characteristics between short- and long-segment Barrett's oesophagus. Aliment Pharmacol Ther 16 (2002) 893-898
25. Vigneri S., Termini R., Leandro G., Badalamenti S., Pantalena M., Savarino V., et al. A comparison of five maintenance therapies for reflux esophagitis. N Engl J Med 333 (1995) 1106-1110
26. Armstrong D., Bennett J.R., Blum A.L., Dent J., De Dombal F.T., Galmiche J.P., et al. The endoscopic assessment of esophagitis. A progress report on observer agreement. Gastroenterology 111 (1996) 85-92
27. Frazzoni M., Lonardo A., Grisendi A., Della Casa G., Pulvirenti M., Ferrari A.M., et al. Are routine duodenal and antral biopsies useful in the management of "functional" dyspepsia? A diagnostic and therapeutic study. J Clin Gastroenterol 17 (1993) 101-108
28. Passaretti S., Zaninotto G., Di Martino N., Leo P., Costantini M., and Baldi F. Standards for oesophageal manometry. A position statement from the Gruppo Italiano di Studio Motilità Apparato Digerente (GISMAD). Dig Liver Dis 32 (2000) 46-55
29. Richter J.E., Bradley L.A., DeMeester T.R., and Wu W.C. Normal 24-h ambulatory esophageal pH values. Influence of study center, pH electrode, age, and gender. Dig Dis Sci 37 (1992) 849-856
30. Ouatu-Lascar R., Fitzgerald R.C., and Triadafilopoulos G. Differentiation and proliferation in Barrett's esophagus and the effects of acid suppression. Gastroenterology 117 (1999) 327-335
31. Dent J. Definition of reflux disease and its separation from dyspepsia. Gut 50 Suppl. IV (2002) iv17-iv20
32. 2RA therapy on nocturnal gastric acid breakthrough. Gastroenterology 122 (2002) 625-632
33. Frazzoni M., De Micheli E., and Savarino V. Different patterns of oesophageal acid exposure distinguish complicated reflux disease from either erosive reflux oesophagitis or non-erosive reflux disease. Aliment Pharmacol Ther 18 (2003) 1091-1098
34. Weusten B.L.A.M., Roelofs J.M.M., Akkermans L.M.A., van Berge-Henegouwen G.P., and Smout A.J.P.M. The symptom-association probability: an improved method for symptom analysis of 24-h esophageal pH data. Gastroenterology 107 (1994) 1741-1745
35. Taghavi S.A., Ghasedi M., Saberi-Firoozi M., Alizadhe-Naeeni M., Bagheri-Lankarani K., Kaviani M.J., et al. Symptom association probability and symptom sensitivity index: preferable but still suboptimal predictors of response to high dose omeprazole. Gut 54 (2005) 1067-1071
36. Pisegna J., Holtmann G., Howden C.W., Katelaris P.H., Sharma P., Spechler S., et al. Review article: oesophageal complications and consequences of persistent gastro-oesophageal reflux disease. Aliment Pharmacol Ther 20 Suppl. 9 (2004) 47-56
37. Wolfsen H.C., Hemminger L.L., Wallace M.B., and Devault K.R. Clinical experience of patients undergoing photodynamic therapy for Barrett's dysplasia or cancer. Aliment Pharmacol Ther 20 (2004) 1125-1131
38. Castell D.O., Murray J.A., Tutuian R., Orlando R.C., and Arnold R. Review article: the pathophysiology of gastro-oesophageal reflux disease-oesophageal manifestations. Aliment Pharmacol Ther 20 Suppl. 9 (2004) 14-25
39. Pace F., and Bianchi Porro G. Gastroesophageal reflux disease: a typical spectrum disease (a new conceptual framework is not needed). Am J Gastroenterol 99 (2004) 946-949
40. Pace F., Bollani S., Molteni P., and Bianchi Porro G. Natural history of gastro-oesophageal reflux disease without oesophagitis (NERD)-a reappraisal 10 years on. Dig Liver Dis 36 (2004) 111-115
41. Ruigomez A., Garcia Rodriguez L.A., Wallander M.A., Johansson S., Graffner H., and Dent J. Natural history of gastro-oesophageal reflux disease diagnosed in general practice. Aliment Pharmacol Ther 20 (2004) 751-760