Gastro-oesophageal reflux of liquids and gas during transient lower oesophageal sphincter relaxations

Neurogastroenterology and Motility

Volumn 18, Issue 10, 2006, Pages 888-893

  Bredenoord, A J ^a   Weusten, B L A M ^a   Timmer, R ^a   Smout, A J P M ^b  

^a ST ANTONIUS HOSPITAL   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Gastro oesophageal reflux; High resolution manometry; Impedance monitoring; Oesophagus; Transient lower oesophageal sphincter relaxation

Indexed keywords

ADULT; ARTICLE; FEMALE; FOOD INTAKE; GAS; GASTROESOPHAGEAL REFLUX; HUMAN; HUMAN EXPERIMENT; IMPEDANCE; LIQUID; LOWER ESOPHAGUS SPHINCTER; MALE; MANOMETRY; NORMAL HUMAN; PH; PRIORITY JOURNAL; STOMACH FUNCTION; STOMACH MOTILITY;

ADULT; ELECTRIC IMPEDANCE; ESOPHAGEAL SPHINCTER, LOWER; FEMALE; GASES; GASTRIC JUICE; GASTROESOPHAGEAL REFLUX; HUMANS; HYDROGEN-ION CONCENTRATION; MALE; MANOMETRY; MIDDLE AGED; MUSCLE RELAXATION; MUSCLE, SMOOTH;

EID: 33748482622     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2006.00817.x     Document Type: Article

References (27)

1. Dent J, Dodds WJ, Friedman RH, Sekiguchi T, Hogan WJ, Arndorfer RC et al. Mechanism of gastroesophageal reflux in recumbent asymptomatic human subjects. J Clin Invest 1980; 65: 256-267.
2. Dodds WJ, Dent J, Hogan WJ, Helm JF, Hauser R, Patel GK et al. Mechanisms of gastroesophageal reflux in patients with reflux esophagitis. N Engl J Med 1982; 307: 1547-1552.
3. Penagini R, Carmagnola S, Cantu P, Allocca M, Bianchi PA. Mechanoreceptors of the proximal stomach: Role in triggering transient lower esophageal sphincter relaxation. Gastroenterology 2004; 126: 49-56.
4. Martin CJ, Patrikios J, Dent J. Abolition of gas reflux and transient lower esophageal sphincter relaxation by vagal blockade in the dog. Gastroenterology 1986; 91: 890-896.
5. Boulant J, Fioramonti J, Dapoigny M, Bommelaer G, Bueno L. Cholecystokinin and nitric oxide in transient lower esophageal sphincter relaxation to gastric distention in dogs. Gastroenterology 1994; 107: 1059-1066.
6. Clave P, Gonzalez A, Moreno A, Lopez R, Farre A, Cusso X et al. Endogenous cholecystokinin enhances postprandial gastroesophageal reflux in humans through extrasphincteric receptors. Gastroenterology 1998; 115: 597-604.
7. Mittal RK, Holloway R, Dent J. Effect of atropine on the frequency of reflux and transient lower esophageal sphincter relaxation in normal subjects. Gastroenterology 1995; 109: 1547-1554.
8. Penagini R, Bianchi PA. Effect of morphine on gastroesophageal reflux and transient lower esophageal sphincter relaxation. Gastroenterology 1997; 113: 409-414.
9. Hirsch DP, Holloway RH, Tytgat GN, Boeckxstaens GE. Involvement of nitric oxide in human transient lower esophageal sphincter relaxations and esophageal primary peristalsis. Gastroenterology 1998; 115: 1374-1380.
10. Lehmann A, Antonsson M, Bremner-Danielsen M, Flardh M, Hansson-Branden L, Karrberg L. Activation of the GABA(B) receptor inhibits transient lower esophageal sphincter relaxations in dogs. Gastroenterology 1999; 117: 1147-1154.
11. Frisby CL, Mattsson JP, Jensen JM, Lehmann A, Dent J, Blackshaw LA. Inhibition of transient lower esophageal sphincter relaxation and gastroesophageal reflux by metabotropic glutamate receptor ligands. Gastroenterology 2005; 129: 995-1004.
12. Kahrilas PJ, Gupta RR. Mechanisms of acid reflux associated with cigarette smoking. Gut 1990; 31: 4-10.
13. Bredenoord AJ, Weusten BL, Timmer R, Smout AJ. Minimum sample frequency for multichannel intraluminal impedance measurement of the oesophagus. Neurogastroenterol Motil 2004; 16: 713-719.
14. Sifrim D, Holloway R, Silny J, Xin Z, Tack J, Lerut A et al. Acid, nonacid, and gas reflux in patients with gastroesophageal reflux disease during ambulatory 24-hour pH-impedance recordings. Gastroenterology 2001; 120: 1588-1598.
15. Holloway RH, Penagini R, Ireland AC. Criteria for objective definition of transient lower esophageal sphincter relaxation. Am J Physiol 1995; 268: G128-G133.
16. Bredenoord AJ, Weusten BL, Timmer R, Smout AJ. Sleeve sensor versus high-resolution manometry for the detection of transient lower esophageal sphincter relaxations. Am J Physiol Gastrointest Liver Physiol 2005; 288: G1190-G1194.
17. Bredenoord AJ, Weusten BL, Timmer R, Smout AJ. Intermittent spatial separation of diaphragm and lower esophageal sphincter favors acidic and Weakly acidic reflux. Gastroenterology 2006; 130: 334-340.
18. Mittal RK, McCallum RW. Characteristics of transient lower esophageal sphincter relaxation in humans. Am J Physiol 1987; 252: G636-G641.
19. Scheffer RC, Gooszen HG, Hebbard G, Samsom M. The role of transsphincteric pressure and proximal gastric volume in acid reflux before and after fundoplication. Gastroenterology 2005; 129: 1900-1909.
20. Wildi SM, Tutuian R, Castell DO. The influence of rapid food intake on postprandial reflux: studies in healthy volunteers. Am J Gastroenterol 2004; 99: 1645-1651.
21. Weusten BL, Akkermans LM, Vanberge-Henegouwen GP, Smout AJ. Symptom perception in gastroesophageal reflux disease is dependent on spatiotemporal reflux characteristics. Gastroenterology 1995; 108: 1739-1744.
22. Emerenziani S, Zhang X, Blondeau K, Silny J, Tack J, Janssens J et al. Gastric fullness, physical activity, and proximal extent of gastroesophageal reflux. Am J Gastroenterol 2005; 100: 1251-1256.
23. Sifrim D, Tack J, Lerut T, Janssens J. Transient lower esophageal sphincter relaxations and esophageal body muscular contractile response in reflux esophagitis. Dig Dis Sci 2000; 45: 1293-1300.
24. Sifrim D. Relevance of volume and proximal extent of reflux in gastro-oesophageal reflux disease. Gut 2005; 54: 178.
25. Gidda JS, Goyal RK. Influence of successive vagal stimulations on contractions in esophageal smooth muscle of opossum. J Clin Invest 1983; 71: 1095-1103.
26. Dodds WJ, Christensen J, Dent J, Wood JD, Arndorfer RC. Esophageal contractions induced by vagal stimulation in the opossum. Am J Physiol 1978; 235: E392-E401.
27. Rattan S, Goyal RK. Neural control of the lower esophageal sphincter: influence of the vagus nerves. J Clin Invest 1974; 54: 899-906.