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European Journal of Cancer Part A
Volumn 32, Issue 9, 1996, Pages 1504-1509
Phase i pharmacokinetics and limited sampling strategies for the bioreductive alkylating drug eo9
Author keywords

Bioreductive agents; Chemotherapy; EO9; Limited sampling methods; Pharmacokinetics; Phase i
Indexed keywords

EID: 33748473253     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (2)
References (12)
  • 1
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    • (1994) Oncology Res , vol.6 , pp. 519-523
    • Verweij, J.1    Aamdal, S.2    Schellens, J.3    Koier, I.4    Lund, B.5
  • 2
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    • EO9: A novel bioreductive alkylating indoloquinone with preferential solid tumour activity and lack of bone marrow toxicity in preclinical models
    • Hendriks HR, Pizao PE, Berger DP, et al. EO9: a novel bioreductive alkylating indoloquinone with preferential solid tumour activity and lack of bone marrow toxicity in preclinical models. Eur J Cancer 1993, 29A, 897-906.
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    • Hendriks, H.R.1    Pizao, P.E.2    Berger, D.P.3
  • 3
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    • Pharmacokinetics, distribution, and metabolism of the novel bioreductive alkylating indol-oquinone EO9 in rodents
    • Workman P, Binger M, Kooistra KL. Pharmacokinetics, distribution, and metabolism of the novel bioreductive alkylating indol-oquinone EO9 in rodents. Int J Radiat Oncol Biol Phys 1992, 22, 717-720.
    • (1992) Int J Radiat Oncol Biol Phys , vol.22 , pp. 717-720
    • Workman, P.1    Binger, M.2    Kooistra, K.L.3
  • 4
    • 0028338822 scopus 로고
    • Phase I and pharmacologic study of the novel indoloquinone bioreductive alkylating cytotoxic drug EO9
    • Schellens JHM, Planting AST, van Acker BAC, et al. Phase I and pharmacologic study of the novel indoloquinone bioreductive alkylating cytotoxic drug EO9. J Natl Cancer Inst 1994, 86, 906-912.
    • (1994) J Natl Cancer Inst , vol.86 , pp. 906-912
    • Schellens, J.H.M.1    Planting, A.S.T.2    Van Acker, B.A.C.3
  • 5
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    • Phase I study of the bioreductive indoloquinone EO9
    • Lund B, Aamdal S, Koier I. Phase I study of the bioreductive indoloquinone EO9. Ann Oncol 1994, S5, 136.
    • (1994) Ann Oncol , vol.5 , pp. 136
    • Lund, B.1    Aamdal, S.2    Koier, I.3
  • 6
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    • Clinical pharmacokinetics-pharmacodynamics of anticancer drugs
    • Evans WE, Relling MV. Clinical pharmacokinetics-pharmacodynamics of anticancer drugs. Clin Pharmacokinet 1989, 16, 327-336.
    • (1989) Clin Pharmacokinet , vol.16 , pp. 327-336
    • Evans, W.E.1    Relling, M.V.2
  • 7
    • 0001473075 scopus 로고
    • Phase II studies with EO9 in breast, colorectal, gastric, pancreatic, and NSCLC
    • Wanders J, Pavlidis N, Gamucci T, et al. Phase II studies with EO9 in breast, colorectal, gastric, pancreatic, and NSCLC. Eur J Cancer 1995, 31 A, 565.
    • (1995) Eur J Cancer , vol.31 , pp. 565
    • Wanders, J.1    Pavlidis, N.2    Gamucci, T.3
  • 8
    • 0027246472 scopus 로고
    • Sensitive isocratic high-performance liquid chromatographic determination of a novel indoloquinone cytotoxic drug (EO9) in human plasma and urine
    • Schellens JH, Loos WJ, Beijnen JH, et al. Sensitive isocratic high-performance liquid chromatographic determination of a novel indoloquinone cytotoxic drug (EO9) in human plasma and urine. J Chromatogr Biomed Appl 1993, 615, 309-315.
    • (1993) J Chromatogr Biomed Appl , vol.615 , pp. 309-315
    • Schellens, J.H.1    Loos, W.J.2    Beijnen, J.H.3
  • 9
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    • A program package for simulation and parameter estimation in pharmacokinetic systems
    • D'Argenio DZ, Schumitzky A. A program package for simulation and parameter estimation in pharmacokinetic systems. Comput Prof Biomed 1979, 9, 115-134.
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    • D'Argenio, D.Z.1    Schumitzky, A.2
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  • 12
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    • Limited sampling model for EO9, a novel indoloquinone cytotoxic drug
    • Schellens JH, Stoter G, Verweij J. Limited sampling model for EO9, a novel indoloquinone cytotoxic drug. Ann Oncol 1994, S5, 170.
    • (1994) Ann Oncol , vol.5 , pp. 170
    • Schellens, J.H.1    Stoter, G.2    Verweij, J.3

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.