Taming the clot-buster tPA

Nature Medicine

Volumn 12, Issue 9, 2006, Pages 993-994

  Dawson, Ted M ^a   Dawson, Valina L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPOPROTEIN RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TISSUE PLASMINOGEN ACTIVATOR;

BLEEDING; BLOOD CLOT; BRAIN HEMORRHAGE; EMERGENCY WARD; FOOD AND DRUG ADMINISTRATION; HUMAN; NONHUMAN; PHYSICIAN; PRIORITY JOURNAL; SHORT SURVEY; STROKE; TREATMENT OUTCOME;

ANIMALS; CEREBROVASCULAR ACCIDENT; HUMANS; OLIGOPEPTIDES; STROKE; TISSUE PLASMINOGEN ACTIVATOR;

EID: 33748447471     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm0906-993     Document Type: Short Survey

References (9)

1. Bambauer, K.Z., Johnston, S.C., Bambauer, D.E. & Zivin, J.A. Arch. Neurol. 63, 661-664 (2006).
2. Armstead, W.M. et al. Neutralizing the neurotoxic effects of exogenous and endogenous tPA. Nat. Neurosci. 9, 1150-1155 (2006).
3. Mitka, M. J. Am. Med. Assoc. 289, 1363-1364 (2003).
4. Lo, E.H. Nat. Med. 10, 1295-1296 (2004).
5. Nicole, O. et al. Nat. Med. 7, 59-64 (2001).
6. Wang, X. et al. Nat. Med. 9, 1313-1317 (2003).
7. Akkawi, S., Nassar, T., Tarshis, M., Cines, D.B. & Higazi, A.A. LRP and alpha(v)beta(3) mediate tPA-activation of smooth muscle cells. Am. J. Physiol. Heart Circ. Physiol. 291, H1351-H1359 (2006).
8. Kilic, E. et al. Stroke 36, 332-336 (2005).
9. Liu, D. et al. Nat. Med. 10, 1379-1383 (2004).