Management of concussion and pos-concussion syndrome

Current Treatment Options in Neurology

Volumn 8, Issue 5, 2006, Pages 415-426

  Willer, Bary ^a   Leddy, John J ^b  

^a UNIVERSITY AT BUFFALO   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMITRIPTYLINE; ANALGESIC AGENT; ANTIDEPRESSANT AGENT; CHOLINESTERASE INHIBITOR; CITICOLINE; DIHYDROERGOTAMINE; DONEPEZIL; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; PHOSPHATIDYLCHOLINE; PHYSOSTIGMINE; PLACEBO; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRAZODONE;

ANAMNESIS; ANTICHOLINERGIC SYNDROME; ATHLETE; BED REST; BRAIN CONCUSSION; BRAIN HEMORRHAGE; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; COGNITIVE DEFECT; COGNITIVE REHABILITATION; COGNITIVE THERAPY; COLD TREATMENT; CONSCIOUSNESS DISORDER; CONVALESCENCE; DEPRESSION; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE EXACERBATION; DISEASE SEVERITY; DIZZINESS; DRUG HALF LIFE; DRUG MECHANISM; EMERGENCY WARD; EVIDENCE BASED MEDICINE; FOLLOW UP; HEADACHE; HUMAN; KINESIOTHERAPY; MANIPULATIVE MEDICINE; MEMORY DISORDER; MENTAL TEST; NEUROIMAGING; NEUROLOGIC EXAMINATION; NONHUMAN; OUTCOMES RESEARCH; PATHOPHYSIOLOGY; PHYSICAL EXAMINATION; POSTCONCUSSION SYNDROME; PRIAPISM; REVIEW; RISK FACTOR; SECOND IMPACT SYNDROME; SLEEP DISORDER; SYMPTOMATOLOGY; TRAUMATIC BRAIN INJURY; TREATMENT PLANNING; UNCONSCIOUSNESS; WAKEFULNESS;

EID: 33748447112     PISSN: 10928480     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11940-006-0031-9     Document Type: Review

References (56)

1. Kraus JF, Sorenson S: Epidemiology. In Neuropsychiatry of Traumatic Brain Injury. Edited by Silver JM, Yudofsky SC, Hales RE. Washington, DC: American Psychiatric Press Inc.; 1994:3-41.
2. Bazarian JJ, McClung J, Cheng YT, et al.: Emergency department management of mild traumatic brain injury in the USA. Emerg Med J 2005, 22:473-477.
3. Bazarian JJ, Blyth B, Cimpello L: Bench to bedside: evidence for brain injury after concussion - looking beyond the computed tomography scan. Acad Emerg Med 2006, 13:199-214.
4. Kelly JP, Rosenberg JH: The development of guidelines for the management of concussion in sports. J Head Trauma Rehabil 1998, 13:53-65.
5. Lovell MR, Collins MW, Iverson GL, et al.: Grade 1 or "ding" concussions in high school athletes. Am J Sports Med 2004, 32:47-54.
6. Thurman DJ, Branche CM, Sniezek JE: The epidemiology of sports-related brain injuries in the United States: recent developments. J Head Trauma Rehabil 1998, 13:1-8.
7. Longhi L, Saatman KE, Fujimoto S, et al.: Temporal window of vulnerability to repetitive experimental concussive brain injury. Neurosurgery 2005, 56:364-374.
8. Lovell M, Iverson G, Collins M, et al.: Does loss of consciousness predict neuropsychological decrements after concussion? Clin J Sport Med 1999, 9:193-198.
9. Guskiewicz KM, Bruce SL, Cantu RC, et al.: Research based recommendations on management of sport related concussion: summary of the National Athletic Trainers' Association position statement. Br J Sports Med 2006, 40:6-10.
10. Giza CC, Hovda DA: The neurometabolic cascade of concussion. J Athl Train 2001, 36:228-235.
11. Pellman EJ, Lovell MR, Viano DC, Casson IR. Concussion in professional football: recovery of NFL and high school athletes assessed by computerized neuropsychological testing - part 12. Neurosurgery 2006, 58:263-274.
12. McCrory P, Johnston K, Meeuwisse W, et al.: Summary and agreement statement of the 2nd International Conference on Concussion in Sport, Prague 2004. Clin J Sport Med 2005, 15:48-55.
13. Boake C, McCauley SP, Levin HS, et al.: Diagnostic criteria for postconcussional syndrome after mild to moderate traumatic brain injury. J Neuropsychiatry Clin Neurosci 2005, 17:350-356.
14. Iverson GL, Gaetz M, Lovell MR, Collins MW: Cumulative effects of concussion in amateur athletes. Brain Inj 2004,18:433-443.
15. Iverson GL, Brooks BL, Lovell MR, Collins MW. No cumulative effects for one or two previous concussions. Br J Sports Med 2006, 40:72-75.
16. McCauley SR, Boake C, Levin HS, et al.: Postconcussional disorder following mild to moderate traumatic brain injury: anxiety, depression, and social support as risk factors and comorbidities. J Clin Exp Neuropsychol 2001, 23:792-808.
17. Bazarian JJ, Atabald S: Predicting postconcussion syndrome after minor traumatic brain injury. Acad Emerg Med 2001, 8:788-795.
18. Korn A, Golan H, Melamed I, et al.: Focal cortical dysfunction and blood-brain barrier disruption in patients with postconcussion syndrome. J Clin Neurophysiol 2005, 22:1-9.
19. McCrory PR, Berkovic SF: Video analysis of acute motor and convulsive manifestations in sport-related concussion. Neurology 2000, 54:1488-1491.
20. Peterson CL, Ferrara MS, Mrazik M, et al.: Evaluation of neuropsychological domain scores and postural stability following cerebral concussion in sports. Clin J Sport Med 2003, 13:230-237.
21. Guskiewicz KM: Assessment of postural stability following sport-related concussion. Curr Sports Med Rep 2003, 2:24-30.
22. Dunning J, Stratford-Smith P, Lecky F, et al.: A meta-analysis of clinical correlates that predict significant intracranial injury in adults with minor head trauma. J Neurotrauma 2004, 21:877-885.
23. Stiell IG, Clement CM, Rowe BH, et al.: Comparison of the Canadian CT Head Rule and the New Orleans Criteria in patients with minor head injury. JAMA 2005, 294:1511-1518.
24. Guskiewicz KM, Bruce SL, Cantu RC, et al.: Recommendations on management of sport-related concussion: summary of the National Athletic Trainers' Association position statement. Neurosurgery 2004, 55:891-895; discussion 896.
25. de Louw A, Twijnstra A, Leffers P: Lack of uniformity and low compliance concerning wake-up advice following head trauma. Ned Tijdschr Geneeskd 1994, 138:2197-2199.
26. de Kruijk JR, Leffers P, Meerhoff S, et al.: Effectiveness of bed rest after mild traumatic brain injury: a randomised trial of no versus six days of bed rest. J Neurol Neurosurg Psychiatry 2002, 73:167-172.
27. Ponsford J, Willmott C, Rothwell A, et al.: Impact of early intervention on outcome following mild head injury in adults. J Neurol Neurosurg Psychiatry 2002, 73:330-332.
28. Wade DT, King NS, Wenden FJ, et al.: Routine follow up, after head injury: a second randomised controlled trial. J Neurol Neurosurg Psychiatry 1998, 65:177-183.
29. Lee ST, Liu TN, Wong CW, et al.: Relative risk of deterioration after mild closed head injury. Acta Neurochir (Wien) 1995,135:136-140.
30. Solomon S: Posttraumatic headache. Med Clin North Am 2001, 85:987-996, vii-viii.
31. Weight DG: Minor head trauma. Psychiatr Clin North Am 1998, 21:609-624.
32. Hall RC, Hall RC, Chapman MJ: Definition, diagnosis, and forensic implications of postconcussional syndrome. Psychosomatics 2005, 46:195-202.
33. Saran A: Antidepressants not effective in headache associated with minor dosed head injury. Int J Psychiatry Med 1988, 18:75-83.
34. Tyler GS, McNeely HE, Dick ML: Treatment of posttraumatic headache with amitriptyline. Headache 1980, 20:213-216.
35. McBeath JG, Nanda A: Use of dihydroergotamine in patients with postconcussion syndrome. Headache 1994,34:148-151.
36. Jensen OK, Nielsen FF, Vosmar L: An open study comparing manual therapy with the use of cold packs in the treatment of post-traumatic headache. Cephalalgia 1990, 10:241-250.
37. Comper P, Bisschop SM, Carnide N, Tricco A: A systematic review of treatments for mild traumatic brain injury. Brain Inj 2005, 19:863-880.
38. Cobb S, Battin B: Second-impact syndrome. J Sch Nurs 2004, 20:262-267.
39. Agrawal D, Gowda NK, Bal CS, et al.: Is medial temporal injury responsible for pediatric postconcussion syndrome? A prospective controlled study with single-photon emission computerized tomography. J Neurosurg 2005, 102(Suppl 2):167-171.
40. Stalnacke BM, Bjornstig U, Karlsson K, Sojka P: One-year follow-up of mild traumatic brain injury: post-concussion symptoms, disabilities and life satisfaction in relation to serum levels of S-100B and neurone-specific enolase in acute phase. J Rehabil Med 2005, 37:300-305.
41. Gaetz M, Weinberg H: Electrophysiological indices of persistent post-concussion symptoms. Brain Inj 2000, 14:815-832.
42. Arciniegas DB, Topkoff JL: Applications of the P50 evoked response to the evaluation of cognitive impairments after traumatic brain injury. Phys Med Rehabil Clin N Am 2004, 15:177-203, viii.
43. Ho MR, Bennett TL: Efficacy of neuropsychological rehabilitation for mild-moderate traumatic brain injury. Arch Clin Neuropsychol 1997, 12:1-11.
44. Cicerone KD: Remediation of "working attention" in mild traumatic brain injury. Brain Inj 2002, 16:185-195.
45. Mittenberg W, Canyock EM, Condit D, Patton C: Treatment of post-concussion syndrome following mild head injury. J Clin Exp Neuropsychol 2001, 23:829-836.
46. Fann JR, Uomoto JM, Katon WJ: Sertraline in the treatment of major depression following mild traumatic brain injury. J Neuropsychiatry Clin Neurosci 2000, 12:226-232.
47. Zasler ND: Mild traumatic brain injury: medical assessment and intervention. J Head Trauma Rehabil 1993, 8:13-29.
48. Zafonte RD, Cullen N, Lexell J: Serotonin agents in the treatment of acquired brain injury. J Head Trauma Rehabil 2002, 17:322-334.
49. Griffin SL, van Reekum R, Masanic C: A review of cholinergic agents in the treatment of neurobehavioral deficits following traumatic brain injury. J Neuropsychiatry Clin Neurosci 2003, 15:17-26.
50. Cardenas DD, McLean A Jr, Farrell-Roberts L, et al.: Oral physostigmine and impaired memory in adults with brain injury. Brain Inj 1994, 8:579-587.
51. Levin HS, Peters BH, Kalisky Z, et al.: Effects of oral physostigmine and lecithin on memory and attention in dosed head-injured patients. Cent Nerv Syst Rauma 1986, 3:333-342.
52. Levin HS: Treatment of postconcussional symptoms with CDP-choline. J Neurol Sci 1991, 103(Suppl):S39-S42.
53. Rogers SL, Doody RS, Mohs RC, Friedhoff LT: Donepezil improves cognition and global function in Alzheimer disease: a 15-week, double-blind, placebo-controlled study. Donepezil Study Group. Arch Intern Med 1998, 158:1021-1031.
54. Masanic CA, Bayley MT, VanReekum R, Simard M: Open-label study of donepezil in traumatic brain injury. Arch Phys Med Rehabil 2001, 82:896-901.
55. Whelan FJ, Walker MS, Schultz SK: Donepezil in the treatment of cognitive dysfunction associated with traumatic brain injury. Ann Clin Psychiatry 2000, 12:131-135.
56. Henninger N, Dutzmann S, Sicard KM, et al.: Impaired spatial learning in a novel rat model of mild cerebral concussion injury. Exp Neurol 2005, 195:447-457.