Hepatocyte targeting of nucleic acid complexes and liposomes by a T7 phage p17 peptide

Molecular Pharmaceutics

Volumn 3, Issue 4, 2006, Pages 386-397

  Wong, So C ^a   Wakefield, Darren ^a   Klein, Jason ^a   Monahan, Sean D ^a   Rozema, David B ^a   Lewis, David L ^a   Higgs, Lori ^a   Ludtke, James ^b   Sokoloff, Alex V ^b   Wolff, Jon A ^b,c  

^a Mirus Bio Corporation   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Gene delivery; Hepatocyte; Liposome; Nucleic acid; p17; siRNA; T7 phage; Tail fiber protein; Targeting

Indexed keywords

LIPOSOME; NUCLEIC ACID; POLYMER; PROTEIN P17; RECOMBINANT PROTEIN; SMALL INTERFERING RNA; VIRUS VECTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BACTERIOPHAGE T7; BIOTINYLATION; CIRCULAR DICHROISM; CONTROLLED STUDY; GENE THERAPY; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; ULTRACENTRIFUGATION;

AMINO ACID SEQUENCE; ANIMALS; BACTERIOPHAGE T7; BASE SEQUENCE; CARBOCYANINES; FLUORESCENT DYES; GENE TARGETING; GENE THERAPY; GENETIC VECTORS; HEPATOCYTES; LIPOSOMES; MICE; MICE, INBRED ICR; MOLECULAR SEQUENCE DATA; NUCLEIC ACIDS; PEPTIDE FRAGMENTS; RNA, SMALL INTERFERING; VIRAL PROTEINS;

EID: 33748445663     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp050108r     Document Type: Article

References (29)

1. Wu, J.; Nantz, M. H.; Zern, M. A. Front. Biosci. 2002, 7, d717-25.
2. Ghosh, S. S.; Takahashi, M.; Thummala, N. R.; Parashar, B.; Chowdhury, N. R.; Chowdhury, J. R. J. Hepatol. 2000, 32, 238-52.
3. Nguyen, T. H.; Ferry, N. Gene Ther. 2004, 11 (Suppl. 1), S76-84.
4. Tuschl, T.; Zamore, P. D.; Lehmann, R.; Bartel, D. P.; Sharp, P. A. Genes Dev. 1999, 13, 3191-7.
5. Morrissey, D. V.; Lockridge, J. A.; Shaw, L.; Blanchard, K.; Jensen, K.; Breen, W.; Hartsough, K.; Machemer, L.; Radka, S.; Jadhav, V.; Vaish, N.; Zinnen, S.; Vargeese, C.; Bowman, K.; Shaffer, C. S.; Jeffs, L. B.; Judge, A.; Maclachlan, I.; Polisky, B. Nat. Biotechnol. 2005, 23 (8), 1002-7.
6. McCaffrey, A. P.; Meuse, L.; Pham, T. T.; Conklin, D. S.; Hannon, G. J.; Kay, M. A. Nature 2002, 418, 38-9.
7. Fire, A.; Xu, S.; Montgomery, M. K.; Kostas, S. A.; Driver, S. E.; Mello, C. C. Nature 1998, 391, 806-11.
8. Crombie, C.; Fraser, A. Lancet 2005, 365, 1288-90.
9. Lieber, A.; He, C. Y.; Meuse, L.; Schowalter, D.; Kirillova, I.; Winther, B.; Kay, M. A. J. Virol. 1997, 71, 8798-807.
10. Pfeifer, A.; Verma, I. M. Annu. Rev. Genomics Hum. Genet. 2001, 2, 177-211.
11. Meijer, D. K.; Molema, G. Semin. Liver Dis. 1995, 15, 202-56.
12. Seymour, L. W.; Ferry, D. R.; Anderson, D.; Hesslewood, S.; Julyan, P. J.; Poyner, R.; Doran, J.; Young, A. M.; Buttles, S.; Kerr, D. J. J. Clin. Oncol. 2002, 20, 1668-76.
13. Rensen, P. C.; Sliedregt, L. A.; Ferns, M.; Kieviet, E.; van Rossenberg, S. M.; van Leeuwen, S. H.; van Berkel, T. J.; Biessen, E. A. J. Biol. Chem. 2001, 276, 37577-84.
14. Biessen, E. A. L.; Bakkeren, H. F.; Beuting, D. M.; Kuiper, J.; van Berkel, T. J. C. Biochem. J. 1994, 299, 291-6.
15. Lee, Y. C.; Townsend, R. R.; Hardy, M. R.; Longren, J.; Arnarp, J.; Haraldsson, M.; Lonn, H. J. Biol. Chem. 1983, 258, 199-202.
16. Fiume, L.; Cerenzia, M. R.; Bonino, F.; Busi, C.; Mattioli, A.; Brunetto, M. R.; Chiaberge, E.; Verme, G. Lancet 1988, 2, 13-5.
17. Lorenz, C.; Hadwiger, P.; John, M.; Vornlocher, H. P.; Unverzagt, C. Bioorg. Med. Chem. Lett. 2004, 14, 4975-7.
18. Soutschek, J.; Akinc, A.; Bramlage, B.; Charisse, K.; Constien, R.; Donoghue, M.; Elbashir, S.; Geick, A.; Hadwiger, P.; Harborth, J.; John, M.; Kesavan, V.; Lavine, G.; Pandey, R. K.; Racie, T.; Rajeev, K. G.; Rohl, I.; Toudjarska, I.; Wang, G.; Wuschko, S.; Bumcrot, D.; Koteliansky, V.; Limmer, S.; Manoharan, M.; Vornlocher, H. P. Nature 2004, 432, 173-8.
19. Sokoloff, A. V.; Bock, I.; Zhang, G.; Hoffman, S.; Dama, J.; Ludtke, J. J.; Cooke, A. M.; Wolff, J. A. Mol. Ther. 2001, 3, 821-30.
20. Sokoloff, A. V.; Wong, S. C.; Ludtke, J. J.; Sebestyen, M. G.; Subbotin, V. M.; Zhang, G.; Budker, T.; Bachhuber, M.; Sumita, Y.; Wolff, J. A. Mol. Ther. 2003, 8, 867-72.
21. Studier, F. W. Virology 1969, 39, 562-74.
22. Wakefield, D. H.; Klein, J. J.; Wolff, J. A.; Rozema, D. B. Bioconjugate Chem. 2005, 16, 1204-8.
23. Rozema, D. B.; Ekena, K.; Lewis, D. L.; Loomis, A. G.; Wolff, J. A. Bioconjugate Chem. 2003, 14, 51-7.
24. Naganawa, A.; Ichikawa, Y.; Isobe, M. T. Tetrahedron 1994, 21, 8969.
25. Aronov, O.; Horowitz, A. T.; Gabizon, A.; Gibson, D. Bioconjugate Chem. 2003, 14, 563-74.
26. Neish, C. S.; Martin, I. L.; Henderson, R. M.; Edwardson, J. M. Br. J. Pharmacol. 2002, 135, 1943-50.
27. Henry, C. M. In Chem. Eng. News 2003, 81 (51), 32-6.
28. Adami, R. C.; Rice, K. G. J. Pharm. Sci. 1999, 88, 739-46.
29. Trubetskoy, V. S.; Loomis, A.; Slattum, P. M.; Hagstrom, J. E.; Budker, V. G.; Wolff, J. A. Bioconjugate Chem. 1999, 10, 624-8.