메뉴 건너뛰기




Volumn 8, Issue 5, 2006, Pages 356-364

Fibrate therapy in patients with metabolic syndrome and diabetes mellitus

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ANGIOTENSIN RECEPTOR ANTAGONIST; ATORVASTATIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BEZAFIBRATE; CLOFIBRATE; CREATINE KINASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; EZETIMIBE; FENOFIBRATE; FIBRIC ACID DERIVATIVE; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPOPROTEIN; NICOTINIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; SIMVASTATIN; TRIACYLGLYCEROL;

EID: 33748433528     PISSN: 15233804     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11883-006-0032-x     Document Type: Review
Times cited : (12)

References (70)
  • 1
    • 4143058119 scopus 로고    scopus 로고
    • The triglyceride-high-density lipoprotein axis: An important target of therapy?
    • Szapary PO, Rader DJ: The triglyceride-high-density lipoprotein axis: an important target of therapy? Am Heart J 2004;148:211-21.
    • (2004) Am Heart J , vol.148 , pp. 211-221
    • Szapary, P.O.1    Rader, D.J.2
  • 2
    • 33646406560 scopus 로고    scopus 로고
    • Dual roles of apolipoprotein CI in the formation of atherogenic remnants
    • Björkegren J: Dual roles of apolipoprotein CI in the formation of atherogenic remnants. Curr Atheroscler Rep 2006, 8:1-2.
    • (2006) Curr Atheroscler Rep , vol.8 , pp. 1-2
    • Björkegren, J.1
  • 3
    • 0345620788 scopus 로고    scopus 로고
    • Hypertriglyceridemia: Changes in the plasma lipoproteins associated with an increased risk of cardiovascular disease
    • Brewer HB Jr: Hypertriglyceridemia: changes in the plasma lipoproteins associated with an increased risk of cardiovascular disease. Am J Cardiol 1999, 83:3F-12F.
    • (1999) Am J Cardiol , vol.83
    • Brewer Jr., H.B.1
  • 4
    • 22544456615 scopus 로고    scopus 로고
    • Postprandial increase of plasma apoAV concentrations in Type 2 diabetic patients
    • Pruneta-Deloche V, Ponsin G, Groisne L, et al.: Postprandial increase of plasma apoAV concentrations in Type 2 diabetic patients. Atherosclerosis 2005, 181:403-405.
    • (2005) Atherosclerosis , vol.181 , pp. 403-405
    • Pruneta-Deloche, V.1    Ponsin, G.2    Groisne, L.3
  • 5
    • 2942683360 scopus 로고    scopus 로고
    • Lipoprotein remnants and endothelial dysfunction in the postprandial phase
    • Maria Maggi F, Raselli S, Grigore L, et al.: Lipoprotein remnants and endothelial dysfunction in the postprandial phase. J Clin Endocrinol Metab 2004, 89:2946-2950.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2946-2950
    • Maria Maggi, F.1    Raselli, S.2    Grigore, L.3
  • 6
    • 0037317156 scopus 로고    scopus 로고
    • Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance
    • Garvey WT, Kwon S, Zheng D, et al.: Effects of insulin resistance and type 2 diabetes on lipoprotein subclass particle size and concentration determined by nuclear magnetic resonance. Diabetes 2003, 52:453-462.
    • (2003) Diabetes , vol.52 , pp. 453-462
    • Garvey, W.T.1    Kwon, S.2    Zheng, D.3
  • 7
    • 0037126526 scopus 로고    scopus 로고
    • Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report
    • Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report. Circulation 2002, 106:3143-3421.
    • (2002) Circulation , vol.106 , pp. 3143-3421
  • 8
    • 24144484876 scopus 로고    scopus 로고
    • The metabolic syndrome: Time for a critical appraisal: Joint statement from the Am Diabetes Association and the European Association for the Study of Diabetes
    • Kahn R, Buse J, Ferrannini E, et al.: The metabolic syndrome: time for a critical appraisal: joint statement from the Am Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2005, 28:2289-2304.
    • (2005) Diabetes Care , vol.28 , pp. 2289-2304
    • Kahn, R.1    Buse, J.2    Ferrannini, E.3
  • 9
    • 27444443876 scopus 로고    scopus 로고
    • Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement
    • Grundy SM, Cleeman JI, Daniels SR, et al.: Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005, 112:2735-2752.
    • (2005) Circulation , vol.112 , pp. 2735-2752
    • Grundy, S.M.1    Cleeman, J.I.2    Daniels, S.R.3
  • 10
    • 28044452217 scopus 로고    scopus 로고
    • Effect of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study); randomized controlled trial
    • The FIELD Study Investigators
    • The FIELD Study Investigators: Effect of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study); randomized controlled trial. Lancet 2005, 366:1849-1861.
    • (2005) Lancet , vol.366 , pp. 1849-1861
  • 11
    • 0023232216 scopus 로고
    • Helsinki Heart Study: Primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease
    • Frick MH, Elo O, Haapa K, et al.: Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N Eng J Med 1987, 317:1237-1245.
    • (1987) N Eng J Med , vol.317 , pp. 1237-1245
    • Frick, M.H.1    Elo, O.2    Haapa, K.3
  • 12
    • 0035941990 scopus 로고    scopus 로고
    • Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: The Diabetes Atherosclerosis Intervention Study, a randomised study
    • The DAIS Investigators
    • The DAIS Investigators: Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: the Diabetes Atherosclerosis Intervention Study, a randomised study. Lancet 2001, 357:905-910.
    • (2001) Lancet , vol.357 , pp. 905-910
  • 13
    • 33645170936 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor ligand bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease
    • Tenenbaum A, Motro M, Fisman EZ, et al.: Peroxisome proliferator-activated receptor ligand bezafibrate for prevention of type 2 diabetes mellitus in patients with coronary artery disease. Circulation 2000, 102:21-27.
    • (2000) Circulation , vol.102 , pp. 21-27
    • Tenenbaum, A.1    Motro, M.2    Fisman, E.Z.3
  • 14
    • 0033527030 scopus 로고    scopus 로고
    • Gemfibrozil for the secondary prevention of coronary disease in men with low levels of high-density lipoprotein cholesterol
    • for the Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group
    • Rubins HB, Robins SJ, Collins D, et al., for the Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group: Gemfibrozil for the secondary prevention of coronary disease in men with low levels of high-density lipoprotein cholesterol. N Eng J Med 1999, 341:410-418.
    • (1999) N Eng J Med , vol.341 , pp. 410-418
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3
  • 15
    • 3142729178 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines
    • for the Coordinating Committee of the National Cholesterol Education Program
    • Grundy SM, Cleeman JI, Bairey Merz CN, et al., for the Coordinating Committee of the National Cholesterol Education Program: Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines. Circulation 2004, 110:227-239.
    • (2004) Circulation , vol.110 , pp. 227-239
    • Grundy, S.M.1    Cleeman, J.I.2    Bairey Merz, C.N.3
  • 16
    • 32144448938 scopus 로고    scopus 로고
    • Standards of medical care in diabetes: 2006
    • American Diabetes Association
    • American Diabetes Association: Standards of medical care in diabetes: 2006. Diabetes Care 2006, 29(Suppl) S18-S19.
    • (2006) Diabetes Care , vol.29 , Issue.SUPPL.
  • 17
    • 0026597808 scopus 로고
    • Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease. Risk in the Helsinki Heart Study. Implications for treatment
    • Manninen V, Tenkanen L, Koskinen P, et al.: Joint effects of serum triglyceride and LDL cholesterol and HDL cholesterol concentrations on coronary heart disease. Risk in the Helsinki Heart Study. Implications for treatment. Circulation 1992, 85:37-45.
    • (1992) Circulation , vol.85 , pp. 37-45
    • Manninen, V.1    Tenkanen, L.2    Koskinen, P.3
  • 18
    • 0026710526 scopus 로고
    • Coronary heart disease incidence in NIDDM patients in the Helsinki Heart Study
    • Koskinen P, Manttari M, Manninen V, et al.: Coronary heart disease incidence in NIDDM patients in the Helsinki Heart Study. Diabetes Care 1992, 15:820-825.
    • (1992) Diabetes Care , vol.15 , pp. 820-825
    • Koskinen, P.1    Manttari, M.2    Manninen, V.3
  • 19
    • 14844292088 scopus 로고    scopus 로고
    • Fenofibrate reduces progression to microalbuminuria over 3 years in a placebo-controlled study in type 2 diabetes: Results from the Diabetes Atherosclerosis Intervention Study (DAIS)
    • Ansquer JC, Foucher C, Rattier S, et al.: Fenofibrate reduces progression to microalbuminuria over 3 years in a placebo-controlled study in type 2 diabetes: Results from the Diabetes Atherosclerosis Intervention Study (DAIS). Am J Kidney Dis 2005, 45:485-493.
    • (2005) Am J Kidney Dis , vol.45 , pp. 485-493
    • Ansquer, J.C.1    Foucher, C.2    Rattier, S.3
  • 20
    • 0037049366 scopus 로고    scopus 로고
    • Diabetes, plasma insulin, and cardiovascular disease subgroup analysis from the Department of Veterans Affairs High-Density Lipoprotein Intervention Trial (VA-HIT)
    • for the VA-HIT Study Group
    • Rubins HB, Robins SJ, Collins D, et al., for the VA-HIT Study Group: Diabetes, plasma insulin, and cardiovascular disease subgroup analysis from the Department of Veterans Affairs High-Density Lipoprotein Intervention Trial (VA-HIT). Arch Intern Med 2002, 162:2597-2604.
    • (2002) Arch Intern Med , vol.162 , pp. 2597-2604
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3
  • 21
    • 0042669791 scopus 로고    scopus 로고
    • Insulin resistance and cardiovascular events with low hdl cholesterol the Veterans Affairs HDL Intervention Trial (VA-HIT)
    • on behalf of the VA-HIT Study Group
    • Robins SJ, Rubins HB, Faas FH, et al., on behalf of the VA-HIT Study Group: Insulin resistance and cardiovascular events with low hdl cholesterol the Veterans Affairs HDL Intervention Trial (VA-HIT). Diabetes Care 2003, 26:1513-1517.
    • (2003) Diabetes Care , vol.26 , pp. 1513-1517
    • Robins, S.J.1    Rubins, H.B.2    Faas, F.H.3
  • 22
    • 33645741889 scopus 로고    scopus 로고
    • Low-density lipoprotein and high-density lipoprotein particle predict coronary events and are favorably changed by gemfibrozil therapy in the Veterans Affairs HDL Intervention Trial
    • In press
    • Otvos J, Collins D, Freedman DS, et al.: Low-density lipoprotein and high-density lipoprotein particle predict coronary events and are favorably changed by gemfibrozil therapy in the Veterans Affairs HDL Intervention Trial Circulation 2006, In press.
    • (2006) Circulation
    • Otvos, J.1    Collins, D.2    Freedman, D.S.3
  • 23
    • 19344375593 scopus 로고    scopus 로고
    • Bezafibrate for the secondary prevention of myocardial infarction in patients with metabolic syndrome
    • Tenenbaum A, Motro M, Fisman EZ, et al.: Bezafibrate for the secondary prevention of myocardial infarction in patients with metabolic syndrome. Arch Intern Med 2005, 165:1154-1160.
    • (2005) Arch Intern Med , vol.165 , pp. 1154-1160
    • Tenenbaum, A.1    Motro, M.2    Fisman, E.Z.3
  • 24
    • 31944435884 scopus 로고    scopus 로고
    • Relation between on-treatment increments in serum high-density lipoprotein cholesterol levels and cardiac mortality in patients with coronary heart disease (from the Bezafibrate Infarction Prevention Trial)
    • Goldenberg I, Goldbourt U, Boyko V, et al.: Relation between on-treatment increments in serum high-density lipoprotein cholesterol levels and cardiac mortality in patients with coronary heart disease (from the Bezafibrate Infarction Prevention Trial). Am J Cardiol 2006, 97:466-471.
    • (2006) Am J Cardiol , vol.97 , pp. 466-471
    • Goldenberg, I.1    Goldbourt, U.2    Boyko, V.3
  • 25
    • 0842325905 scopus 로고    scopus 로고
    • High fasting glucose levels as a predictor of worse clinical outcome in patients with coronary artery disease: Results from the Bezafibrate Infarction Prevention (BIP) study
    • Arcavi L, Behar S, Caspi A, et al.: High fasting glucose levels as a predictor of worse clinical outcome in patients with coronary artery disease: results from the Bezafibrate Infarction Prevention (BIP) study. Am Heart J 2004, 147:239-245.
    • (2004) Am Heart J , vol.147 , pp. 239-245
    • Arcavi, L.1    Behar, S.2    Caspi, A.3
  • 26
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90056 participants in 14 randomised trials of statins
    • Cholesterol Treatment Trialists' (CTT) Collaborators
    • Cholesterol Treatment Trialists' (CTT) Collaborators: Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90056 participants in 14 randomised trials of statins. Lancet 2005, 366:1267-1278.
    • (2005) Lancet , vol.366 , pp. 1267-1278
  • 27
    • 33748414993 scopus 로고    scopus 로고
    • The Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial
    • Available at Accessed March 5
    • The Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Available at http://www.accordtrial.org/public/index.cfm. Accessed March 5, 2006.
    • (2006)
  • 28
    • 13844272245 scopus 로고    scopus 로고
    • Effectiveness and tolerability of simvastatin plus fenofibrate for combined hyperlipidemia (The SAFARI Trial)
    • Grundy SM, Vega GL, Yuan Z, et al.: Effectiveness and tolerability of simvastatin plus fenofibrate for combined hyperlipidemia (The SAFARI Trial). Am J Cardiol 2005, 95:462-468.
    • (2005) Am J Cardiol , vol.95 , pp. 462-468
    • Grundy, S.M.1    Vega, G.L.2    Yuan, Z.3
  • 29
    • 2542431095 scopus 로고    scopus 로고
    • Qualitative effect of fenofibrate and quantitative effect of atorvastatin in combined dyslipidemia with small dense LDL
    • Winkler K, Weltzien P: Qualitative effect of fenofibrate and quantitative effect of atorvastatin in combined dyslipidemia with small dense LDL. Exp Clin Endocrinol Diabetes 2004, 112:241-247.
    • (2004) Exp Clin Endocrinol Diabetes , vol.112 , pp. 241-247
    • Winkler, K.1    Weltzien, P.2
  • 30
    • 18944381282 scopus 로고    scopus 로고
    • Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia
    • Koh KK, Quon MJ, Han SH, et al.: Additive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia. J Am Coll Cardiol 2005, 45:1649-1653.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1649-1653
    • Koh, K.K.1    Quon, M.J.2    Han, S.H.3
  • 31
    • 18744365508 scopus 로고    scopus 로고
    • Efficacy and safety of the coadministration of ezetimibe with fenofibrate in patients with mixed hyperlipidaemia
    • for the Ezetimibe Study Group
    • Farnier M, Freeman MW, Macdonell G, et al., for the Ezetimibe Study Group: Efficacy and safety of the coadministration of ezetimibe with fenofibrate in patients with mixed hyperlipidaemia. Eur Heart J 2005, 26:897-905.
    • (2005) Eur Heart J , vol.26 , pp. 897-905
    • Farnier, M.1    Freeman, M.W.2    Macdonell, G.3
  • 32
    • 0029792297 scopus 로고    scopus 로고
    • Effect of a combination of gemfibrozil and niacin on lipid levels
    • Spencer GA, Wirebaugh S, Whitney EJ: Effect of a combination of gemfibrozil and niacin on lipid levels J Clin Pharmacol 1996, 36:696-700.
    • (1996) J Clin Pharmacol , vol.36 , pp. 696-700
    • Spencer, G.A.1    Wirebaugh, S.2    Whitney, E.J.3
  • 33
    • 19944426989 scopus 로고    scopus 로고
    • A randomized trial of a strategy for increasing high-density lipoprotein cholesterol levels: Effects on progression of coronary heart disease and clinical events
    • Whitney EJ, Krasuski RA, Personius BE, et al.: A randomized trial of a strategy for increasing high-density lipoprotein cholesterol levels: effects on progression of coronary heart disease and clinical events. Ann Intern Med 2005, 142:95-104.
    • (2005) Ann Intern Med , vol.142 , pp. 95-104
    • Whitney, E.J.1    Krasuski, R.A.2    Personius, B.E.3
  • 34
    • 0036183630 scopus 로고    scopus 로고
    • The mechanisms of action of PPARs
    • Berger J, Moller DE: The mechanisms of action of PPARs. Annu Rev Med 2002, 53:409-435.
    • (2002) Annu Rev Med , vol.53 , pp. 409-435
    • Berger, J.1    Moller, D.E.2
  • 35
    • 33644652183 scopus 로고    scopus 로고
    • Sorting out the roles of PPAR-a in energy metabolism and vascular homeostasis
    • Lefebvre P, Chinetti G, Fruchart JC, Staels B: Sorting out the roles of PPAR-a in energy metabolism and vascular homeostasis. J Clin Invest 2006, 116:571-580.
    • (2006) J Clin Invest , vol.116 , pp. 571-580
    • Lefebvre, P.1    Chinetti, G.2    Fruchart, J.C.3    Staels, B.4
  • 36
    • 0842304656 scopus 로고    scopus 로고
    • PPARa controls the intracellular coenzyme A concentration via regulation of PANK1a gene expression
    • Ramaswamy G, Karim MA, Gopal Murti K, Jackowski S: PPARa controls the intracellular coenzyme A concentration via regulation of PANK1a gene expression. J Lipid Res 2004, 45:17-31.
    • (2004) J Lipid Res , vol.45 , pp. 17-31
    • Ramaswamy, G.1    Karim, M.A.2    Gopal Murti, K.3    Jackowski, S.4
  • 37
    • 27444440394 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha is required for feedback regulation of highly unsaturated fatty acid synthesis
    • Li Y, Nara TY, Nakamura MT: Peroxisome proliferator-activated receptor alpha is required for feedback regulation of highly unsaturated fatty acid synthesis. J Lipid Res 2005;46:2432-2440.
    • (2005) J Lipid Res , vol.46 , pp. 2432-2440
    • Li, Y.1    Nara, T.Y.2    Nakamura, M.T.3
  • 38
    • 0036801615 scopus 로고    scopus 로고
    • Effect of gemfibrozil on apolipoprotein B secretion and diacylglycerol acyltransferase activity in human hepatoblastoma (HepG2) cells
    • Zhu D, Ganji SH, Kamanna VS, Kashyap ML: Effect of gemfibrozil on apolipoprotein B secretion and diacylglycerol acyltransferase activity in human hepatoblastoma (HepG2) cells. Atherosclerosis 2002, 164:221-228.
    • (2002) Atherosclerosis , vol.164 , pp. 221-228
    • Zhu, D.1    Ganji, S.H.2    Kamanna, V.S.3    Kashyap, M.L.4
  • 39
    • 0029941224 scopus 로고    scopus 로고
    • Fenofibrate reduces plasma cholesteryl ester transfer from HDL to VLDL and normalizes the atherogenic dense LDL profile in combined hyperlipidemia
    • Guerin M, Bruckert E, Dolphin PJ, et al.: Fenofibrate reduces plasma cholesteryl ester transfer from HDL to VLDL and normalizes the atherogenic dense LDL profile in combined hyperlipidemia. Arterioscler Thromb Vasc Biol 1996, 16:763-772.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 763-772
    • Guerin, M.1    Bruckert, E.2    Dolphin, P.J.3
  • 40
    • 0029994543 scopus 로고    scopus 로고
    • Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression
    • Schoonjans K, Staels B, Auwerx J: Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression J Lipid Res 1996, 37:907-925.
    • (1996) J Lipid Res , vol.37 , pp. 907-925
    • Schoonjans, K.1    Staels, B.2    Auwerx, J.3
  • 41
    • 0032819192 scopus 로고    scopus 로고
    • Cell culture conditions determine apolipoprotein CIII secretion and regulation by fibrates in human hepatoma HepG2 cells
    • Fruchart JC, Dallongeville J, Staels B: Cell culture conditions determine apolipoprotein CIII secretion and regulation by fibrates in human hepatoma HepG2 cells. Cell Physiol Biochem 1999, 9:139-149.
    • (1999) Cell Physiol Biochem , vol.9 , pp. 139-149
    • Fruchart, J.C.1    Dallongeville, J.2    Staels, B.3
  • 42
    • 23244459004 scopus 로고    scopus 로고
    • Administration of a PPAR-a agonist increases serum apolipoprotein A-V levels and the apolipoprotein A-V/apolipoprotein C-III ratio
    • Schultze AE, Alborn WE, Newton RK, et al.: Administration of a PPAR-a agonist increases serum apolipoprotein A-V levels and the apolipoprotein A-V/apolipoprotein C-III ratio. J. Lipid Res 2005, 46:1591-1595.
    • (2005) J. Lipid Res , vol.46 , pp. 1591-1595
    • Schultze, A.E.1    Alborn, W.E.2    Newton, R.K.3
  • 43
    • 0037211980 scopus 로고    scopus 로고
    • Micronized fenofibrate normalizes the enhanced lipidemic response to a fat load in patients with type 2 diabetes and optimal glucose control
    • Cavallero E, Dachet C, Assadolahi F, et al.: Micronized fenofibrate normalizes the enhanced lipidemic response to a fat load in patients with type 2 diabetes and optimal glucose control. Atherosclerosis 2003, 166:151-161.
    • (2003) Atherosclerosis , vol.166 , pp. 151-161
    • Cavallero, E.1    Dachet, C.2    Assadolahi, F.3
  • 44
    • 0037324362 scopus 로고    scopus 로고
    • Short-term triglyceride lowering with fenofibrate improves vasodilator function in subjects with hypertriglyceridemia
    • Capell WH, DeSouza CA, Poirier B, et al.: Short-term triglyceride lowering with fenofibrate improves vasodilator function in subjects with hypertriglyceridemia. Arterioscler Thromb Vasc Biol 2003, 23:307-313.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 307-313
    • Capell, W.H.1    DeSouza, C.A.2    Poirier, B.3
  • 45
    • 20144373625 scopus 로고    scopus 로고
    • Fenofibric acid, an active form of fenofibrate, increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter A1 gene in a liver X receptor-dependent manner
    • Arakawa R, Tamehiro N, Nishimaki-Mogami T, et al.: Fenofibric acid, an active form of fenofibrate, increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter A1 gene in a liver X receptor-dependent manner. Arterioscler Thromb Vasc Biol 2005, 25:1193-1197.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1193-1197
    • Arakawa, R.1    Tamehiro, N.2    Nishimaki-Mogami, T.3
  • 46
    • 0344874601 scopus 로고    scopus 로고
    • Fibrates in 2003: Therapeutic action in atherogenic dyslipidaemia and future perspectives
    • Chapman JM: Fibrates in 2003: therapeutic action in atherogenic dyslipidaemia and future perspectives. Atherosclerosis 2003, 171:1-13.
    • (2003) Atherosclerosis , vol.171 , pp. 1-13
    • Chapman, J.M.1
  • 47
    • 12144288053 scopus 로고    scopus 로고
    • Fibrates modify the expression of key factors involved in bile-acid synthesis and biliary-lipid secretion in gallstone patients
    • Roglans N, Vazquez-Carrera M, Alegret M: Fibrates modify the expression of key factors involved in bile-acid synthesis and biliary-lipid secretion in gallstone patients. Eur J Clin Pharmacol 2004, 59:855-861.
    • (2004) Eur J Clin Pharmacol , vol.59 , pp. 855-861
    • Roglans, N.1    Vazquez-Carrera, M.2    Alegret, M.3
  • 48
    • 0036840634 scopus 로고    scopus 로고
    • Effects of various fibrates on serum alkaline phosphatase activity
    • Ganotakis E, Tsimihodimos V, Bairaktari E, et al.: Effects of various fibrates on serum alkaline phosphatase activity. Atherosclerosis 2002, 165:187-188.
    • (2002) Atherosclerosis , vol.165 , pp. 187-188
    • Ganotakis, E.1    Tsimihodimos, V.2    Bairaktari, E.3
  • 49
    • 30844462540 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha controls cellular cholesterol trafficking in macrophages
    • Chinetti-Gbaguidi G, Rigamonti E, Helin L, et al.: Peroxisome proliferator-activated receptor alpha controls cellular cholesterol trafficking in macrophages. J Lipid Res 2005, 46:2717-2725.
    • (2005) J Lipid Res , vol.46 , pp. 2717-2725
    • Chinetti-Gbaguidi, G.1    Rigamonti, E.2    Helin, L.3
  • 50
    • 0035138625 scopus 로고    scopus 로고
    • PPAR-a and PPAR-a activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway
    • Chinetti G, Lestavel S, Bocher V, et al.: PPAR-a and PPAR-a activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Nat Med 2001, 7:53-58.
    • (2001) Nat Med , vol.7 , pp. 53-58
    • Chinetti, G.1    Lestavel, S.2    Bocher, V.3
  • 51
    • 29244484585 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: How their effects on macrophages can lead to the development of a new drug therapy against atherosclerosis
    • Li AC, Palinsk W: Peroxisome proliferator-activated receptors: how their effects on macrophages can lead to the development of a new drug therapy against atherosclerosis. Annu Rev Pharmacol Toxicol 2006, 46:1-39.
    • (2006) Annu Rev Pharmacol Toxicol , vol.46 , pp. 1-39
    • Li, A.C.1    Palinsk, W.2
  • 52
    • 0025993346 scopus 로고
    • Discrete subspecies of human low density lipoproteins are heterogeneous in their interaction with the cellular LDL receptor
    • Nigon F, Lesnik P, Rouis M, et al.: Discrete subspecies of human low density lipoproteins are heterogeneous in their interaction with the cellular LDL receptor. J Lipid Res 1991, 32:1741-1753.
    • (1991) J Lipid Res , vol.32 , pp. 1741-1753
    • Nigon, F.1    Lesnik, P.2    Rouis, M.3
  • 53
    • 6044233001 scopus 로고    scopus 로고
    • Role of fibric acid derivatives in the management of risk factors for coronary heart disease
    • Despres JP, Lemieux I, Robins SJ: Role of fibric acid derivatives in the management of risk factors for coronary heart disease. Drugs 2004, 64:2177-2198.
    • (2004) Drugs , vol.64 , pp. 2177-2198
    • Despres, J.P.1    Lemieux, I.2    Robins, S.J.3
  • 54
    • 26444604923 scopus 로고    scopus 로고
    • Effect of bezafibrate on incidence of type 2 diabetes mellitus in obese patients
    • Tenenbaum A, Motrol M, Fisman EZ, et al.: Effect of bezafibrate on incidence of type 2 diabetes mellitus in obese patients. Eur Heart J 2005, 26:2032-2038.
    • (2005) Eur Heart J , vol.26 , pp. 2032-2038
    • Tenenbaum, A.1    Motrol, M.2    Fisman, E.Z.3
  • 55
    • 19944379835 scopus 로고    scopus 로고
    • Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hypertriglyceridemia
    • Koh KK, Han FS, Quon MJ, et al.: Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hypertriglyceridemia. Diabetes Care 2005, 28:1419-1424.
    • (2005) Diabetes Care , vol.28 , pp. 1419-1424
    • Koh, K.K.1    Han, F.S.2    Quon, M.J.3
  • 56
    • 1842788708 scopus 로고    scopus 로고
    • Effect of micronized fenofibrate on insulin resistance in patients with metabolic syndrome
    • Wysocki J, Belowski D, Kalina M, et al.: Effect of micronized fenofibrate on insulin resistance in patients with metabolic syndrome, Int J Clin Pharmacol 2004, 42:212-217.
    • (2004) Int J Clin Pharmacol , vol.42 , pp. 212-217
    • Wysocki, J.1    Belowski, D.2    Kalina, M.3
  • 57
    • 10044223533 scopus 로고    scopus 로고
    • PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis
    • Li AC, Glass CK: PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis. J Lipid Res 2004;45:2161-73.
    • (2004) J Lipid Res , vol.45 , pp. 2161-2173
    • Li, A.C.1    Glass, C.K.2
  • 58
    • 2342485967 scopus 로고    scopus 로고
    • Effects of fenofibrate on lipoproteins, vasomotor function, and serological markers of inflammation, plaque stabilization, and hemostasis
    • Koh KK, Ahn JY, Han SH, et al.: Effects of fenofibrate on lipoproteins, vasomotor function, and serological markers of inflammation, plaque stabilization, and hemostasis Atherosclerosis 2004, 174:379-383.
    • (2004) Atherosclerosis , vol.174 , pp. 379-383
    • Koh, K.K.1    Ahn, J.Y.2    Han, S.H.3
  • 60
    • 0036122333 scopus 로고    scopus 로고
    • Elevated soluble cellular adhesion molecules in subjects with low HDL-cholesterol
    • Calabresi L, Gomaraschi M, Villa B, et al.: Elevated soluble cellular adhesion molecules in subjects with low HDL-cholesterol. Arterioscler Thromb Vasc Biol 2002, 22:656-661.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 656-661
    • Calabresi, L.1    Gomaraschi, M.2    Villa, B.3
  • 61
    • 0036364909 scopus 로고    scopus 로고
    • Fenofibrate increases creatininemia by increasing metabolic production of creatinine
    • Hottelart C, Esper NE, Rose E, Achard JM: Fenofibrate increases creatininemia by increasing metabolic production of creatinine. Nephron 2002, 92:536-541.
    • (2002) Nephron , vol.92 , pp. 536-541
    • Hottelart, C.1    Esper, N.E.2    Rose, E.3    Achard, J.M.4
  • 62
    • 0033659109 scopus 로고    scopus 로고
    • Fibrate-induced increase in BUN and creatinine: Is gemfibrozil the only innocuous agent?
    • Broeders N, Knoop C, Antoine M, et al.: Fibrate-induced increase in BUN and creatinine: is gemfibrozil the only innocuous agent? Nephrol Dial Transplant 2000, 15:1993-1999.
    • (2000) Nephrol Dial Transplant , vol.15 , pp. 1993-1999
    • Broeders, N.1    Knoop, C.2    Antoine, M.3
  • 63
    • 0842346182 scopus 로고    scopus 로고
    • Serum homocysteine concentrations, gemfibrozil treatment, and progression of coronary atherosclerosis
    • Syvanne M, Whittall RA, Turpeinen U, et al.: Serum homocysteine concentrations, gemfibrozil treatment, and progression of coronary atherosclerosis. Atherosclerosis 2004, 172:267-272.
    • (2004) Atherosclerosis , vol.172 , pp. 267-272
    • Syvanne, M.1    Whittall, R.A.2    Turpeinen, U.3
  • 64
    • 1842477680 scopus 로고    scopus 로고
    • Effect of fenofibrate-mediated increase in plasma homocysteine on the progression of coronary artery disease in Type 2 diabetes mellitus
    • Genest J, Frohlich J, Steiner G: Effect of fenofibrate-mediated increase in plasma homocysteine on the progression of coronary artery disease in Type 2 diabetes mellitus. Am J Cardiol 2004, 93:848-853.
    • (2004) Am J Cardiol , vol.93 , pp. 848-853
    • Genest, J.1    Frohlich, J.2    Steiner, G.3
  • 65
    • 0034897294 scopus 로고    scopus 로고
    • Vitamin supplementation can markedly reduce the homocysteine elevation induced by fenofibrate
    • Dierkes J, Westphal S, Kunstmann S, et al.: Vitamin supplementation can markedly reduce the homocysteine elevation induced by fenofibrate. Atherosclerosis 2001, 158:161-164.
    • (2001) Atherosclerosis , vol.158 , pp. 161-164
    • Dierkes, J.1    Westphal, S.2    Kunstmann, S.3
  • 66
    • 0034860421 scopus 로고    scopus 로고
    • Folate supplementation prevents plasma homocysteine increase after fenofibrate therapy
    • Stulc T, Melenovsky V, Grauova B, et al.: Folate supplementation prevents plasma homocysteine increase after fenofibrate therapy. Nutrition 2001, 17:721-723.
    • (2001) Nutrition , vol.17 , pp. 721-723
    • Stulc, T.1    Melenovsky, V.2    Grauova, B.3
  • 67
    • 0036266987 scopus 로고    scopus 로고
    • Mechanistic studies on metabolic interactions between gemfibrozil and statins
    • Prueksaritanont T, Zhao JJ, Ma B, et al.: Mechanistic studies on metabolic interactions between gemfibrozil and statins. J Pharmacol Exp Therapeutics 2002, 301:1042-1051.
    • (2002) J Pharmacol Exp Therapeutics , vol.301 , pp. 1042-1051
    • Prueksaritanont, T.1    Zhao, J.J.2    Ma, B.3
  • 68
    • 11144239674 scopus 로고    scopus 로고
    • Reporting rate of rhabdomyolysis with fenofibrate + statin versus gemfibrozil + any statin
    • Jones PH, Davidson MH: Reporting rate of rhabdomyolysis with fenofibrate + statin versus gemfibrozil + any statin. Am J Cardiol 2005;95:120-122.
    • (2005) Am J Cardiol , vol.95 , pp. 120-122
    • Jones, P.H.1    Davidson, M.H.2
  • 69
    • 27744605739 scopus 로고    scopus 로고
    • Pharmacokinetic interactions between statins and fibrates
    • Corsini A, Bellosta S, Davidson MH: Pharmacokinetic interactions between statins and fibrates. Am J Cardiol 2005, 96(Suppl):44K-49K.
    • (2005) Am J Cardiol , vol.96 , Issue.SUPPL.
    • Corsini, A.1    Bellosta, S.2    Davidson, M.H.3
  • 70
    • 21344475107 scopus 로고    scopus 로고
    • The changing face of cardiovascular risk
    • Grundy SM: The changing face of cardiovascular risk. J Am Coll Cardiol 2005, 46:173-175.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 173-175
    • Grundy, S.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.