Does hyperglycemia reduce proliferation or increase apoptosis? [3]

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 291, Issue 3, 2006, Pages

  Davidson, Sean M ^a   Yellon, Derek M ^a  

^a UNIVERSITY COLLEGE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; GLUCOSE; LIPOCORTIN 5; PROPIDIUM IODIDE; PROTEIN KINASE B; WORTMANNIN;

APOPTOSIS; CARDIOVASCULAR RISK; CELL PROLIFERATION; CELL SURVIVAL; DIABETES MELLITUS; ENDOTHELIUM CELL; FLOW CYTOMETRY; HUMAN; HYPERGLYCEMIA; LETTER; PRIORITY JOURNAL; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; CELL COUNT; CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; GLUCOSE; HUMANS; HYPERGLYCEMIA; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 33748427644     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00301.2006     Document Type: Letter

References (4)

1. Han H, Long H, Wang H, Wang J, Zhang Y, and Wang Z. Progressive apoptotic cell death triggered by transient oxidative insult in H9c2 rat ventricular cells: a novel pattern of apoptosis and the mechanisms. Am J Physiol Heart Circ Physiol 286: H2169-H2182, 2004
2. Hanada M, Feng J, and Hemmings BA. Structure, regulation and function of PKB/AKT - a major therapeutic target. Biochim Biophys Acta 1697: 3-16, 2004.
3. 2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway. Cell Signal 18: 391-399, 2006.
4. Varma S, Lal BK, Zheng R, Breslin JW, Saito S, Pappas PJ, Hobson RW II, and Duran WN. Hyperglycemia alters PI3k and Akt signaling and leads to endothelial cell proliferative dysfunction. Am J Physiol Heart Circ Physiol 289: H1744-H1751, 2005.