Rapid vasoregulatory mechanisms in exercising human skeletal muscle: Dynamic response to repeated changes in contraction intensity

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 291, Issue 3, 2006, Pages

  Rogers, Anna M ^a   Saunders, Natasha R ^a   Pyke, Kyra E ^a   Tschakovsky, Michael E ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Blood flow dynamics; Exercise hyperemia; Muscle pump; Rapid vasodilation

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; DOPPLER FLOWMETRY; ECHOGRAPHY; ELECTROCARDIOGRAM; EXERCISE; FEMALE; FOREARM BLOOD FLOW; HEART CYCLE; HEART RATE; HUMAN; MALE; MEAN ARTERIAL PRESSURE; MUSCLE BLOOD FLOW; MUSCLE CONTRACTION; MUSCLE RELAXATION; NORMAL HUMAN; OSCILLATION; PRIORITY JOURNAL; SKELETAL MUSCLE; TONOMETRY;

ADULT; BLOOD PRESSURE; EXERCISE; FEMALE; HAND STRENGTH; HEART RATE; HUMANS; HYPEREMIA; MALE; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE, SKELETAL; REGIONAL BLOOD FLOW; TIME FACTORS; VASODILATION;

EID: 33748425446     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00368.2006     Document Type: Article

References (22)

1. Clifford PS and Hellsten Y. Vasodilatory mechanisms in contracting skeletal muscle. J Appl Physiol 97: 393-403, 2004.
2. Clifford PS, Kluess HA, Hamann JJ, Buckwalter JB, and Jasperse JL. Mechanical compression elicits vasodilatation in skeletal muscle feed arteries. J Physiol 572: 561-567, 2006.
3. Dyke CK, Dietz NM, Lennon RL, Warner DO, and Joyner MJ. Forearm blood flow responses to handgripping after local neuromuscular blockade. J Appl Physiol 84: 754-758, 1998.
4. Hamann JJ, Buckwalter JB, and Clifford PS. Vasodilatation is obligatory for contraction-induced hyperaemia in canine skeletal muscle. J Physiol 557: 1013-1020, 2004.
5. Laughlin MH and Korzick DH. Vascular smooth muscle: integrator of vasoactive signals during exercise hyperemia. Med Sci Sports Exerc 33: 81-91, 2001.
6. Mihok ML and Murrant CL. Rapid biphasic arteriolar dilations induced by skeletal muscle contraction are dependent on stimulation characteristics. Can J Physiol Pharmacol 82: 282-287, 2004.
7. Mohrman DE and Sparks HV. Myogenic hyperemia following brief tetanus of canine skeletal muscle. Am J Physiol 227: 531-535, 1974.
8. Mohrman DE and Sparks HV. Role of potassium ions in the vascular response to a brief tetanus. Circ Res 35: 384-390, 1974.
9. Naik JS, Valic Z, Buckwalter JB, and Clifford PS. Rapid vasodilation in response to a brief tetanic muscle contraction. J Appl Physiol 87: 1741-1746, 1999.
10. Saunders NR, Dinenno FA, Pyke KE, Rogers AM, and Tschakovsky ME. Impact of combined nitric oxide and prostaglandin blockade on rapid vasodilation in a forearm mild-to-moderate exercise transition in humans. Am J Physiol Heart Circ Physiol 288: H214-H220, 2005.
11. Saunders NR and Tschakovsky ME. Evidence for a rapid vasodilatory contribution to immediate hyperemia in rest-to-mild and mild-to-moderate forearm exercise transitions in humans. J Appl Physiol 97: 1143-1151, 2004.
12. Shepherd JT. Circulation to skeletal muscle. In: Handbook of Physiology. The Cardiovascular System. Peripheral Circulation and Organ Blood Flow. Bethesda, MD: Am. Physiol. Soc., 1983, sect. 2, vol. III, chapt. 11, p. 319-370.
13. Sheriff DD. Muscle pump function during locomotion: mechanical coupling of stride frequency and muscle blood flow. Am J Physiol Heart Circ Physiol 284: H2185-H2191, 2003.
14. Sheriff DD, Rowell LB, and Scher AM. Is rapid rise in vascular conductance at onset of dynamic exercise due to muscle pump? Am J Physiol Heart Circ Physiol 265: H1227-H1234, 1993.
15. Sheriff DD and Zidon TM. Delay of muscle vasodilation to changes in work rate (treadmill grade) during locomotion. J Appl Physiol 94: 1903-1909, 2003.
16. Shoemaker JK and Hughson RL. Adaptation of blood flow during the rest to work transition in humans. Med Sci Sports Exerc 31: 1019-1026, 1999.
17. Tschakovsky ME and Hughson RL. Rapid blunting of sympathetic vasoconstriction in the human forearm at the onset of exercise. J Appl Physiol 94: 1785-1792, 2003.
18. Tschakovsky ME, Rogers AM, Pyke KE, Saunders NR, Glenn N, Lee SJ, Weissgerber T, and Dwyer EM. Immediate exercise hyperemia in humans is contraction intensity dependent: evidence for rapid vasodilation. J Appl Physiol 96: 639-644, 2004.
19. Tschakovsky ME and Sheriff DD. Immediate exercise hyperemia: contributions of the muscle pump vs. rapid vasodilation. J Appl Physiol 97: 739-747, 2004.
20. Tschakovsky ME, Shoemaker JK, and Hughson RL. Vasodilation and muscle pump contribution to immediate exercise hyperemia. Am J Physiol Heart Circ Physiol 271: H1697-H1701, 1996.
21. VanTeeffelen JW and Segal SS. Rapid dilation of arterioles with single contraction of hamster skeletal muscle. Am J Physiol Heart Circ Physiol 290: H119-H127, 2006.
22. Wunsch SA, Muller-Delp J, and Delp MD. Time course of vasodilatory responses in skeletal muscle arterioles: role in hyperemia at onset of exercise. Am J Physiol Heart Circ Physiol 279: H1715-H1723, 2000.