Overcoming the "valley of death": Mouse models to accelerate translational research

Diabetes Technology and Therapeutics

Volumn 8, Issue 3, 2006, Pages 413-414

  Friedl, Karl E ^a  

^a U S ARMY RESEARCH INSTITUTE OF ENVIRONMENTAL MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD GLUCOSE MONITORING; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE MODEL; GLUCOSE METABOLISM; MEDICAL RESEARCH; MILITARY MEDICINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VALIDATION PROCESS; ANIMAL; EXPERIMENTAL DIABETES MELLITUS; RESEARCH; RESEARCH ETHICS; STANDARD;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; ETHICS, RESEARCH; MICE; RESEARCH;

EID: 33748421945     PISSN: 15209156     EISSN: None     Source Type: Journal    
DOI: 10.1089/dia.2006.8.413     Document Type: Article

References (5)

1. National Research Council: Accelerating Technology Transition-Bridging the Valley of Death for Materials and Processes in Defense Systems. Washington, DC: National Academies Press, 2004. Available online at http://darwin.nap.edu/ html/accel-tech/0309093171. pdf (accessed March 19, 2006).
2. Klueh U, Liu Z, Cho B, Ouyang T, Feldman B, Henning TP, Kaur M, Kreutzer D: Continuous glucose monitoring in normal mice and mice with prediabetes and diabetes. Diabetes Technol Ther 2006;8:402-412.
3. Klueh U, Kreutzer DL: Murine model of implantable glucose sensors: a novel model for glucose sensor development. Diabetes Technol Ther 2005;7:727-737.
4. Leiter EH, Reifsnyder PC: Differential levels of diabetogenic stress in two new mouse models of obesity and type 2 diabetes. Diabetes 2004;53(Suppl 1):S4-S11.
5. Klonoff DC: Continuous glucose monitoring-road-map for 21st century diabetes therapy. Diabetes Care 2005;28:1231-1239.