A possible dose-dependent teratogenic effect of ergotamine

Reproductive Toxicology

Volumn 22, Issue 3, 2006, Pages 551-552

  Acs N ^a   Banhidy F ^a   Puho E ^b   Czeizel, A E ^b  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b FOUNDATION FOR THE COMMUNITY CONTROL OF HEREDITARY DISEASES   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPHENAZONE; BELLADONNA ALKALOID; CAFFEINE; ERGOTAMINE; KEFALGIN;

ARTHROGRYPOSIS; CARDIOVASCULAR MALFORMATION; CLEFT LIP PALATE; ESOPHAGUS ATRESIA; FEMALE; GESTATION PERIOD; HEADACHE; HUMAN; HUNGARY; HYPOSPADIAS; KIDNEY AGENESIS; KIDNEY MALFORMATION; LETTER; MIGRAINE; MOEBIUS SYNDROME; NEURAL TUBE DEFECT; NONHUMAN; POLAND SYNDROME; POLYDACTYLY; PREGNANT WOMAN; PRENATAL DRUG EXPOSURE; RISK ASSESSMENT; SPINA BIFIDA; SYNDACTYLY; TERATOGENICITY;

ABNORMALITIES, DRUG-INDUCED; DOSE-RESPONSE RELATIONSHIP, DRUG; ERGOTAMINE; FEMALE; GESTATIONAL AGE; HUMANS; HUNGARY; NEURAL TUBE DEFECTS; PREGNANCY; RETROSPECTIVE STUDIES; VASOCONSTRICTOR AGENTS;

EID: 33748416991     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2006.03.002     Document Type: Letter

References (13)

1. Czeizel A.E. Teratogenicity of ergotamine. J Med Genet 26 (1989) 69-71
2. Medveczky E., Puhó E., and Czeizel A.E. The use of drugs in mothers of offspring with neural-tube defects. Pharmacoepid Drug Saf 13 (2004) 443-455
3. Briggs G.G., Freeman R.K., and Yaffe S.J. Drugs in pregnancy and lactation. 5th ed. (1998), William and Wilkins, Baltimore
4. Czeizel A.E., Rockenbauer M., Siffel C.S., and Varga E. Description and mission evaluation of the Hungarian case-control surveillance of congenital abnormalities, 1980-1996. Teratology 63 (2001) 176-185
5. David T.J. Nature and etiology of Poland anomaly. N Engl J Med 287 (1972) 487-489
6. Graham J.M., Marin-Padilla M., and Hoefnagel D. Jejunal atresia associated with cafergot ingestion during pregnancy. Clin Pediat 22 (1983) 226-228
7. Graf W.D., and Shepard T.H. Uterine contraction in the development of Mobius syndrome. J Child Neurol 12 (1997) 225-227
8. Verloes A., Emonts P., Dubois M., et al. Paraplegia and arthrogryposis of the lower extremities after intrauterine exposure to ertogamine. J Med Genet 27 (1990) 213-214
9. Hughes H.E., and Goldstein D.A. Births defects following maternal exposure to ergotamine, beta blockers, and caffeine. J Med Genet 25 (1988) 396-399
10. Heinonen O.P., Slohe D., and Shapiros. Birth defects and drugs in pregnancy (1977), John Wright-PSG, Mass p. 358-60
11. Grauwiler J., and Shon H. Teratological experiments with ergotamine in mice, rats and rabbits. Teratology 7 (1973) 227-236
12. Schon H., Leist K.H., and Grauwiler J. Single day treatment of pregnant rats ergotamine (abstract). Teratology 11 (1995) 32A
13. Raymond G.V. Teratogen update: ergot and ergotamine. Teratology 51 (1995) 344-347