Blood lactate accumulation: Hemodynamics and acid base status

Journal of Intensive Care Medicine

Volumn 17, Issue 4, 2002, Pages 180-185

  Aduen, Javier F ^a   Burritt, Mary F ^b   Murray, Michael J ^a  

^a MAYO CLINIC   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Acidosis; Alkalosis; Animal study; Hyperlactatemia; Pigs; Vasodilation

Indexed keywords

LACTATE SODIUM; LACTIC ACID;

ACID BASE BALANCE; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; HEMODYNAMICS; LACTATE BLOOD LEVEL; METABOLIC ACIDOSIS; METABOLIC ALKALOSIS; NONHUMAN; PRIORITY JOURNAL; SWINE;

EID: 33748416868     PISSN: 08850666     EISSN: 15251489     Source Type: Journal    
DOI: 10.1177/0885066602017004004     Document Type: Article

References (33)

1. Mizock BA. Lactic acidosis. Disease-a-Month 1989;35:233-300.
2. Chernow B, Aduen J, Bernstein WK, et al. Lactate: the ultimate blood test in critical care? Crit Care 1995;15:253-268.
3. Tonnessen TI. Intracellular pH and electrolyte regulation. In: Grenvik A, Ayres SM, Holbrook PR, et al, eds. Textbook of critical care. 4th ed. Philadelphia: WB Saunders, 2000:507-522.
4. Barnett VT, Schmidt GA. Acid-base disorders. In: Hall JB, Schmidt GA, Wood LDH, eds. Principles of critical care. New York: McGraw-Hill, 1998:1169-1181.
5. Zaritsky AL. Catecholamines, inotropic medications, and vasopressor agents. In: Chernow B, ed. The pharmacologic approach to the critically ill patient. 3rd ed. Baltimore, MD: Williams & Wilkins, 1994:387-404.
6. Carrier O Jr, Cowsert M, Hancock J, et al. Effect of hydrogen ion changes on vascular resistance in isolated artery segments. Am J Physiol 1964;207:168-172.
7. Aduen J, Bernstein WK, Miller J, et al. Relationship between blood lactate concentrations and ionized calcium, glucose, and acid-base status in critically ill and noncritically ill patients. Crit Care Med 1995;23:246-252.
8. Groeneveld AB, Kester AD, Nauta JJ, et al. Relation of arterial blood lactate to oxygen delivery and hemodynamic variables in human shock states. Circ Shock 1987;22:35-53.
9. 2 alpha in canine coronary arteries. Circ Res 1980;46:771-779.
10. McKinnon W, Aaronson PI, Knock G, et al. Mechanism of lactate-induced relaxation of isolated rat mesenteric resistance arteries. J Physiol 1996;490:783-792.
11. + channels. J Mol Cell Cardiol 1998;30:349-356.
12. + channels in skeletal muscle by intracellular protons. Nature 1990;343:375-377.
13. Quayle JM, Nelson MT, Standen NB. ATP-sensitive and inwardly rectifying potassium channels in smooth muscle. Physiol Rev 1997;77:1165-1232.
14. + channel mediates hypotension in endotoxemia and hypoxic lactic acidosis in dog. J Clin Invest 1992;89:2071-2074.
15. Keung EC, Li Q. Lactate activates ATP-sensitive potassium channels in guinea pig ventricular myocytes. J Clin Invest 1991;88:1772-1777.
16. Aduen J, Bernstein WK, Khastgir T, et al. The use and clinical importance of a substrate-specific electrode for rapid determination of blood lactate concentrations. JAMA 1994;272:1678-1685.
17. Institute of Laboratory Animal Resources (US). Guide for the care and use of laboratory animals. Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council. 7th ed. Washington, DC: National Academy Press, 1996.
18. Woll PJ, Records CO. Lactate elimination in man: effects of lactate concentration and hepatic dysfunction. Eur J Clin Invest 1979;9:397-104.
19. +) lactic acid metabolism. Clin Sci 1970;39:271-279.
20. Searle GL, Cavalieri RR. Determination of lactate kinetics in the human analysis of data from single injection vs continuous infusion methods. Proc Soc Exp Biol Med 1972;139:1002-1006.
21. Huseby JS, Gumprecht DG. Hemodynamic effects of rapid bolus hypertonic sodium bicarbonate. Chest 1981;79:552-554.
22. Miller FN, Nolph KD, Joshua IG, et al. Hyperosmolality, acetate, and lactate: dilatory factors during peritoneal dialysis. Kidney Int 1981;20:397-402.
23. Raper RF, Cameron G, Walker D, et al. Type B lactic acidosis following cardiopulmonary bypass. Crit Care Med 1997;25:46-51.
24. Herrero JA, Trobo JI, Torrente J, et al. Hemodialysis with acetate, DL-lactate and bicarbonate: a hemodynamic and gasometric study. Kidney Int 1994;46:1167-1177.
25. Krebs HA, Woods HF, Alberti KGMM. Hyperlactatemia and lactic acidosis. Essays Med Biochem 1975;1:81-103.
26. Maran A, Cranston I, Lomas J, et al. Protection by lactate of cerebral function during hypoglycaemia. Lancet 1994;343:16-20.
27. Cross HR, Clarke K, Opie LH, et al. Is lactate-induced myocardial ischaemic injury mediated by decreased pH or increased intracellular lactate? J Mol Cell Cardiol 1995;27:1369-1381.
28. Levinsky NG. Acidosis and alkalosis. In: Harrison TR, Isselbacher KJ, et al, eds. Princ Intern Med. 13th ed. New York: McGraw-Hill, 1994:253-262.
29. Wilkie DR. Generation of protons by metabolic processes other than glycolysis in muscle cells: a critical view. J Mol Cell Cardiol 1979;11:325-330.
30. Stewart PA. Modern quantitative acid-base chemistry. Can J Physiol Pharmacol 1983;61:1444-1461.
31. Fencl V, Leith DE. Stewart's quantitative acid-base chemistry: applications in biology and medicine. Respir Physiol 1993;91:1-16.
32. Kellum JA. Metabolic acidosis in the critically ill: lessons from physical chemistry. Kidney Int Suppl 1998;66: S81-S86.
33. Leverve XM. Lactic acidosis: a new insight? Minerva Anesthesiol 1999;65:205-209.