Addition of spironolactone to an angiotensin-converting enzyme inhibitor decreases lung congestion and edema in Dahl hypertensive rats

Heart and Vessels

Volumn 21, Issue 4, 2006, Pages 251-255

  Nishi, Isao ^a   Kawano, Satoru ^a   Misaki, Masako ^a   Hoshi, Tomoya ^a   Masumi, Tomoko ^a   Iida, Keiji ^a   Watanabe, Shigeyuki ^a   Yamaguchi, Iwao ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Angiotensin converting enzyme inhibitor; Fibrosis; Heart failure with preserved systolic function; Hypertrophy; Spironolactone

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; IMIDAPRIL; SPIRONOLACTONE; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; HEART FAILURE; HEART LEFT VENTRICLE VOLUME; HEART VENTRICLE FUNCTION; HYPERTENSION; LUNG CONGESTION; LUNG EDEMA; LUNG WEIGHT; MALE; MONOTHERAPY; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; SALT INTAKE; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME;

ALDOSTERONE ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; CARDIAC OUTPUT, LOW; DRUG THERAPY, COMBINATION; HYPERTENSION; IMIDAZOLIDINES; MALE; PULMONARY EDEMA; RATS; RATS, INBRED DAHL; SPIRONOLACTONE;

EID: 33748416630     PISSN: 09108327     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00380-005-0898-5     Document Type: Article

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