Acute ethanol administration decreases GAP-43 and phosphorylated-GAP-43 in the rat hippocampus

Brain Research

Volumn 1112, Issue 1, 2006, Pages 16-25

  Kim, Hyun Joon ^a   Choi, Kyung Mi ^a   Ku, Bo Mi ^a   Mun, Jihye ^a   Joo, Yeon ^a   Han, Jae Yoon ^a   Kim, Young Hee ^a   Roh, Gu Seob ^a   Kang, Sang Soo ^a   Cho, Gyeong Jae ^a   Choi, Wan Sung ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

Author keywords

Ethanol; GAP 43; Hippocampus; LTP; p GAP 43

Indexed keywords

ALCOHOL; MESSENGER RNA; NEUROMODULIN; PROTEIN KINASE C;

ALCOHOL BLOOD LEVEL; ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INHIBITION KINETICS; LONG TERM POTENTIATION; MALE; MEMORY DISORDER; MOSSY FIBER; NERVE CELL PLASTICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REAL TIME POLYMERASE CHAIN REACTION;

ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; GAP-43 PROTEIN; GENE EXPRESSION REGULATION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; PHOSPHORYLATION; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TIME FACTORS;

EID: 33748415442     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.07.018     Document Type: Article

References (41)

1. Alling C., Bergman O., Larsson C., and Simonsson P. Evaluation of ethanol effects on PLC signal transduction pathways using cell lines of neuronal origin. Alcohol Alcohol., Suppl. 2 (1993) 259-295
2. Amaral D.G., and Witter M.P. The three-dimensional organization of the hippocampal formation: a review of anatomical data. Neuroscience 31 (1989) 571-591
3. Benowitz L.I., and Routtenberg A. GAP-43: an intrinsic determinant of neuronal development and plasticity. Trends Neurosci. 20 (1997) 84-91
4. Bliss T.V., and Lomo T. Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J. Physiol. 232 (1973) 331-356
5. Blitzer R.D., Gil O., and Landau E.M. Long-term potentiation in rat hippocampus is inhibited by low concentrations of ethanol. Brain Res. 537 (1990) 203-208
6. Bowden S.C., and McCarter R.J. Spatial memory in alcohol-dependent subjects: using a push-button maze to test the principle of equiavailability. Brain Cogn. 22 (1993) 51-62
7. Cadete-Leite A., Tavares M.A., Uylings H.B., and Paula-Barbosa M. Granule cell loss and dendritic regrowth in the hippocampal dentate gyrus of the rat after chronic alcohol consumption. Brain Res. 473 (1988) 1-14
8. Casoli T., Di Stefano G., Gracciotti N., Fattoretti P., Solazzi M., and Bertoni-Freddari C. Age-related effects of moderate alcohol consumption on GAP-43 levels in rat hippocampus. Mech. Ageing Dev. 122 (2001) 1723-1738
9. Charness M.E. Brain lesions in alcoholics. Alcohol., Clin. Exp. Res. 17 (1993) 2-11
10. Cox T. The effects of caffeine, alcohol, and previous exposure to the test situation on spontaneous alternation. Psychopharmacologia 17 (1970) 83-88
11. Crews F.T., Morrow A.L., Criswell H., and Breese G. Effects of ethanol on ion channels. Int. Rev. Neurobiol. 39 (1996) 283-367
12. Dekker L.V., De Graan P.N., Versteeg D.H., Oestreicher A.B., and Gispen W.H. Phosphorylation of B-50 (GAP-43) is correlated with neurotransmitter release in rat hippocampal slices. J. Neurochem. 52 (1989) 24-30
13. Freund G. Chronic central nervous system toxicity of alcohol. Annu. Rev. Pharmacol. 13 (1973) 217-227
14. Givens B.S., and Breese G.R. Site-specific enhancement of gamma-aminobutyric acid-mediated inhibition of neural activity by ethanol in the rat medial septal area. J. Pharmacol. Exp. Ther. 254 (1990) 528-538
15. Givens B., Williams J.M., and Gill T.M. Septohippocampal pathway as a site for the memory-impairing effects of ethanol. Hippocampus 10 (2000) 111-121
16. Hens J.J., Ghijsen W.E., Dimjati W., Wiegant V.M., Oestreicher A.B., Gispen W.H., and De Graan P.N. Evidence for a role of protein kinase C substrate B-50 (GAP-43) in Ca(2+)-induced neuropeptide cholecystokinin-8 release from permeated synaptosomes. J. Neurochem. 61 (1993) 602-609
17. Holloway F.A. State-dependent effects of ethanol on active and passive avoidance learning. Psychopharmacologia 25 (1972) 238-261
18. Kim H.J., Ha M., Park C.H., Park S.J., Youn S.M., Kang S.S., Cho G.J., and Choi W.S. StAR and steroidogenic enzyme transcriptional regulation in the rat brain: effects of acute alcohol administration. Brain Res. Mol. Brain Res. 115 (2003) 39-49
19. Kim Y.H., Kim Y.S., Kang S.S., Noh H.S., Kim H.J., Cho G.J., and Choi W.S. Expression of 14-3-3 zeta and interaction with protein kinase C in the rat retina in early diabetes. Diabetologia 48 (2005) 1411-1415
20. Leahy J.C., Luo Y., Kent C.S., Meiri K.F., and Vallano M.L. Demonstration of presynaptic protein kinase C activation following long-term potentiation in rat hippocampal slices. Neuroscience 52 (1993) 563-574
21. Lima-Landman M.T., and Albuquerque E.X. Ethanol potentiates and blocks NMDA-activated single-channel currents in rat hippocampal pyramidal cells. FEBS Lett. 247 (1989) 61-67
22. Linden D.J., Sheu F.S., Murakami K., and Routtenberg A. Enhancement of long-term potentiation by cis-unsaturated fatty acid: relation to protein kinase C and phospholipase A2. J. Neurosci. 7 (1987) 3783-3792
23. Linden D.J., Wong K.L., Sheu F.S., and Routtenberg A. NMDA receptor blockade prevents the increase in protein kinase C substrate (protein F1) phosphorylation produced by long-term potentiation. Brain Res. 458 (1988) 142-146
24. Little H.J. Mechanisms that may underlie the behavioural effects of ethanol. Prog. Neurobiol. 36 (1991) 171-194
25. Lovinger D.M., Akers R.F., Nelson R.B., Barnes C.A., McNaughton B.L., and Routtenberg A. A selective increase in phosporylation of protein F1, a protein kinase C substrate, directly related to three day growth of long-term synaptic enhancement. Brain Res. 343 (1985) 137-143
26. Lovinger D.M., Wong K.L., Murakami K., and Routtenberg A. Protein kinase C inhibitors eliminate hippocampal long-term potentiation. Brain Res. 436 (1987) 177-783
27. Lovinger D.M., White G., and Weight F.F. Ethanol inhibits NMDA-activated ion current in hippocampal neurons. Science 243 (1989) 1721-1724
28. Matthews D.B., Simson P.E., and Best P.J. Acute ethanol impairs spatial memory but not stimulus/response memory in the rat. Alcohol., Clin. Exp. Res. 19 (1995) 902-909
29. Matthews D.B., Simson P.E., and Best P.J. Ethanol alters spatial processing of hippocampal place cells: a mechanism for impaired navigation when intoxicated. Alcohol., Clin. Exp. Res. 20 (1996) 404-407
30. Oestreicher A.B., De Graan P.N., Gispen W.H., Verhaagen J., and Schrama L.H. B-50, the growth associated protein-43: modulation of cell morphology and communication in the nervous system. Prog. Neurobiol. 53 (1997) 627-686
31. Perrone-Bizzozero N.I., Cansino V.V., and Kohn D.T. Posttranscriptional regulation of GAP-43 gene expression in PC12 cells through protein kinase C-dependent stabilization of the mRNA. J. Cell Biol. 120 (1993) 1263-1270
32. Perrone-Bizzozero N.I., Isaacson T.V., Keidan G.M., Eriqat C., Meiri K.F., Savage D.D., and Allan A.M. Prenatal ethanol exposure decreases GAP-43 phosphorylation and protein kinase C activity in the hippocampus of adult rat offspring. J. Neurochem. 71 (1998) 2104-2111
33. Ramakers G.M., De Graan P.N., Urban I.J., Kraay D., Tang T., Pasinelli P., Oestreicher A.B., and Gispen W.H. Temporal differences in the phosphorylation state of pre- and postsynaptic protein kinase C substrates B-50/GAP-43 and neurogranin during long-term potentiation. J. Biol. Chem. 270 (1995) 13892-13898
34. Routtenberg A. Protein kinase C activation leading to protein F1 phosphorylation may regulate synaptic plasticity by presynaptic terminal growth. Behav. Neural Biol. 44 (1985) 186-200
35. Ryabinin A.E. Role of hippocampus in alcohol-induced memory impairment: implications from behavioral and immediate early gene studies. Psychopharmacology 139 (1998) 34-43
36. Ryback R.S. Schizophrenics anonymous: a treatment adjunct. Psychiatry Med. 2 (1971) 247-253
37. Silvers J.M., Tokunaga S., Berry R.B., White A.M., and Matthews D.B. Impairments in spatial learning and memory: ethanol, allopregnanolone, and the hippocampus. Brain Res. Brain Res. Rev. 43 (2003) 275-284
38. Simson P.E., Criswell H.E., and Breese G.R. Inhibition of NMDA-evoked electrophysiological activity by ethanol in selected brain regions: evidence for ethanol-sensitive and ethanol-insensitive NMDA-evoked responses. Brain Res. 607 (1993) 9-16
39. Tabakoff B., and Hoffman P.L. Alcohol addiction: an enigma among us. Neuron 16 (1996) 909-912
40. Tokunaga S., McDaniel J.R., Morrow A.L., and Matthews D.B. Effect of acute ethanol administration and acute allopregnanolone administration on spontaneous hippocampal pyramidal cell neural activity. Brain Res. 967 (2003) 273-280
41. Weight F.F. Cellular and molecular physiology of alcohol actions in the nervous system. Int. Rev. Neurobiol. 33 (1992) 289-348