Single dose intravenous toxicity studies of T-3762, a novel parenteral quinolone antimicrobial agent, in rats, dogs and monkeys

Japanese Journal of Antibiotics

Volumn 51, Issue 10, 1998, Pages 15-17

  Nagai, Akio ^a,b   Shibata, Tetsuo ^a   Nagasawa, Mineko ^a   Shiotani, Norio ^a   Miyazaki, Miyono ^a   Kawamura, Yasuhito ^a   Kodama, Takuya ^a   Onimaru, Toshio ^a  

^a TOYAMA CHEMICAL CO LTD   (Japan)

^b SHIN NIPPON BIOMEDICAL LABORATORIES LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PAZUFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ANIMAL EXPERIMENT; ANTIMICROBIAL THERAPY; ARTICLE; DOG; DRUG STRUCTURE; FEMALE; GAIT DISORDER; HISTOPATHOLOGY; INTRAVENOUS DRUG ADMINISTRATION; LETHAL DOSE; LOCOMOTION; LUNG EDEMA; LUNG HEMORRHAGE; MALE; MONKEY; MUSCLE WEAKNESS; MYDRIASIS; NONHUMAN; RAT; RESPIRATORY FAILURE; SALIVATION DISORDER; SURVIVAL RATE; TISSUE NECROSIS; TONIC SEIZURE; TOXICITY TESTING;

ALANINE TRANSAMINASE; ANIMALS; ANTI-INFECTIVE AGENTS; ASPARTATE AMINOTRANSFERASES; CARTILAGE, ARTICULAR; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLUOROQUINOLONES; INJECTIONS, INTRAVENOUS; KIDNEY; LETHAL DOSE 50; LIVER; MACACA FASCICULARIS; MALE; MOTOR ACTIVITY; MOUTH MUCOSA; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATION; RESPIRATORY SYSTEM;

EID: 33748393231     PISSN: 03682781     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)