HIV-discordant couples: An emerging issue in prevention and treatment

Southern African Journal of HIV Medicine

Volumn , Issue 23, 2006, Pages 25-28

  de Bruyn, Guy ^a   Bandezi, Ntombi ^a   Dladla, Sibongile ^a   Gray, Glenda ^a  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ANTIRETROVIRUS AGENT;

ARTICLE; BEHAVIOR; CHEMOPROPHYLAXIS; CONDOM; COUNSELING; EPIDEMIC; HELPER CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN IMMUNODEFICIENCY VIRUS PREVALENCE; INFECTION PREVENTION; INTRAUTERINE INSEMINATION; LYMPHOCYTE COUNT; PREGNANCY; SAFE SEX; SOCIAL ASPECT; SOUTH AFRICA; VIRUS LOAD; VIRUS TRANSMISSION;

EID: 33748375553     PISSN: 16089693     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Robinson NJ, et al. Type of partnership and heterosexual spread of HIV infection in rural Uganda: results from simulation modelling. Int J STD AIDS 1999; 10(11): 718-725.
2. Malamba SS, et al. Couples at risk: HIV-1 concordance and discordance among sexual partners receiving voluntary counseling and testing in Uganda. J Acquir Immune Defic Syndr 2005; 39(5): 576-580.
3. Fideli US, et al. Virologic and immunologic determinants of heterosexual transmission of human immunodeficiency virus type 1 in Africa. AIDS Res Hum Retroviruses 2001; 17(10): 901-910.
4. Quinn TC, et al. Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group. N Engl J Med 2000; 342(13): 921-929.
5. O'Farrell N. Enhanced efficiency of female-to-male HIV transmission in core groups in developing countries: the need to target men. Sex Transm Dis 2001; 28(2): 84-91.
6. Gray R.H, et al. Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda. Lancet 2001; 357: 1149-1153.
7. Freeman EE, Glynn JR, Factors affecting HIV concordancy in married couples in four African cities. AIDS 2004; 18(12): 1715-1721.
8. Auvert B. et al. Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 Trial. PLoS Med, 2005; 2(11): e298.
9. Rogers MC, et al. HIV in couples in South India; implications for prevention. Int J STD AIDS 2005; 16(6): 442-445.
10. Rainwater S, et al. No evidence for rapid subtype C spread within an epidemic in which multiple subtypes and intersubtype recombinants circulate. AIDS Res Hum Retroviruses 2005; 21(12): 1060-1065.
11. Dorak MT, et al. Transmission of HIV-1 and HLA-B allele-sharing within serodiscordant heterosexual Zambian couples. Lancet 2004; 363: 2137-2139.
12. Wawer MJ, et al. Rates of HIV-1 transmission per coital act, by stage of HIV-1 infection, in Rakai, Uganda. J Infect Dis 2005; 191(19): 1403-1409.
13. Louisirirotchanakul S, et al. Genetic analysis of HIV-1 discordant couples in Thailand: association of CCR2 641 homozygosity with HIV-1-negative status. J Acquir Immune Defic Syndr 2002; 29(3): 314-315.
14. Clerici M, et al. Serum IgA of HIV-exposed uninfected individuals inhibit HIV through recognition of a region within the alpha-helix of gp41. AIDS 2002; 16(13): 1731-1741.
15. Gorbach PM, Holmes KK. Transmission of STIs/HIV at the partnership level: beyond individual-level analyses. J Urban Health 2003; 80(4 Suppl 3): 15-25.
16. Bennetts A, et al. Differences in sexual behaviour between HIV-infected pregnant women and their husbands in Bangkok, Thailand. AIDS Care 1999; 11(6): 649-661.
17. Senkoro KP, et al. HIV incidence and HIV-associated mortality in a cohort of factory workers and their spouses in Tanzania, 1991 through 1996. J Acquir Immune Defic Syndr 2000; 23(2): 194-202.
18. Allen S, et al. Sexual behavior of HIV discordant couples after HIV counseling and testing. AIDS 2003; 17(5): 733-740.
19. Roth DL, et al. Sexual practices of HIV discordant and concordant couples in Rwanda: effects of a testing and counselling programme for men. Int J STD AIDS 2001; 12(3): 181-188.
20. Lurie MN, et al. Who infects whom? HIV-1 concordance and discordance among migrant and non-migrant couples in South Africa. AIDS 2003; 17(15): 2245-2252.
21. Morrill AC, Noland C. Interpersonal issues surrounding HIV counseling and testing, and the phenomenon of 'testing by proxy'. J Health Commun 2006; 11(2): 183-198.
22. Robertson G, et al. Couple Counselling and HIV Testing in Soweto: Initial Uptake and Response. Paper presented at the 2nd South African AIDS Conference, Durban, 2005.
23. Bunnell RE, et al. Living with discordance: knowledge, challenges, and prevention strategies of HIV-discordant couples in Uganda. AIDS Care 2005; 17(8): 999-1012.
24. Porter L, et al. HIV status and union dissolution in sub-Saharan Africa: the case of Rakai, Uganda. Demography 2004; 41(3): 465-482.
25. Celum CL, Robinson NJ, Cohen MS. Potential effect of HIV type 1 antiretroviral and herpes simplex virus type 2 antiviral therapy on transmission and acquisition of HIV type 1 infection. J Infect Dis 2005; 191 suppl 1, S107-S114.
26. Committee on Ethics of the American College of Obstetricians and Gynecologists (ACOG) Human immunodeficiency virus: ethical guidelines for obstetricians and gynecologists. In: Ethics in Obstetrics and Gynecology, Washington, DC: ACOG, 2002: 42-47.
27. Henrion R, et al. HIV seropositivity and desire for children. Contracept Fertil Sex 1993; 21(3): 217-221.
28. Vernazza PL, et al. HIV-discordant couples and parenthood: how are we dealing with the risk of transmission? AIDS 2006; 20(4): 635-636.
29. Dunne AL, et al. Analysis of HIV-1 viral load in seminal plasma samples. J Clin Virol 2003; 26(2): 239-245.
30. Kato S, et al. Complete removal of HIV-1 RNA and proviral DNA from semen by the swim-up method: assisted reproduction technique using spermatozoa free from HIV-1. AIDS 2006; 20(7): 967-973.
31. Al-Khan A, et al. Assisted reproductive technology for men and women infected with human immunodeficiency virus type 1. Clin Infect Dis 2003; 36(2): 195-200.
32. Gray RH, et al. Population-based study of fertility in women with HIV-1 infection in Uganda. Lancet 1998; 351: 98-103.