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2 at the end of the electrode and 5 nm gold colloid-oligonucleotide conjugates (i.e., the SET quantum dots) were attached using 1,8-octanedithiol. Although multiple particles are likely present on the electrode, conductance signatures indicate that only one is selected for tunneling.
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33748337561
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note
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Single molecular gates were achieved by either of two methods: (1) purchase of nanoparticle-molecule conjugates from bioreagent supplier (BB1, R&DSystems, Sigma-Genosys, etc.) with gel chromatographic separation of products to obtain only one ligand per nanoparticle or (2) stericly limited self-assembly of ligands onto immobilized QDs via incubation in 1 mM solutions for 12 h (see SI).
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