A biphenotypic transformation of 8p11 myeloproliferative syndrome with CEP1/FGFR1 fusion gene

European Journal of Haematology

Volumn 77, Issue 4, 2006, Pages 349-354

  Yamamoto, Katsuya ^a   Kawano, Hiroki ^a   Nishikawa, Shinichiro ^a   Yakushijin, Kimikazu ^a   Okamura, Atsuo ^a   Matsui, Toshimitsu ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

8p11 myeloproliferative syndrome; B lymphoblast; Biphenotypic transformation; CEP1 FGFR1 fusion transcript; Immunophenotype; Monoblast; t(8; 9)(p11; q33)

Indexed keywords

BUSULFAN; CD14 ANTIGEN; CD19 ANTIGEN; CD2 ANTIGEN; CD20 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; CD4 ANTIGEN; CYCLOPHOSPHAMIDE; DAUNORUBICIN; FIBROBLAST GROWTH FACTOR RECEPTOR 1; HLA DR ANTIGEN; MICROSOMAL AMINOPEPTIDASE; MYELOPEROXIDASE; PREDNISOLONE; VINCRISTINE;

ADULT; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CASE REPORT; CELL DIFFERENTIATION; CELL INFILTRATION; CLINICAL FEATURE; EXON; FEMALE; GENE FUSION; HUMAN; KARYOTYPE; MULTIPLE ORGAN FAILURE; MYELOPROLIFERATIVE DISORDER; PHENOTYPE; PRIORITY JOURNAL; REMISSION; STEM CELL;

BASE SEQUENCE; CELL CYCLE PROTEINS; CHROMOSOMES, HUMAN, PAIR 8; DNA PRIMERS; FEMALE; HUMANS; IMMUNOPHENOTYPING; KARYOTYPING; MIDDLE AGED; MYELOPROLIFERATIVE DISORDERS; POLYMERASE CHAIN REACTION; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; TRANSFORMATION, GENETIC;

EID: 33748357533     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2006.00723.x     Document Type: Article

References (20)

1. MACDONALD D, REITER A, CROSS NCP. The 8p11 myeloproliferative syndrome: a distinct clinical entity caused by constitutive activation of FGFR1. Acta Haematol 2002;107:101-107.
2. MICHAUX L, MECUCCI C, VELLOSO ERP, DIERLAMM J, CRIEL A, LOUWAGIE A, VAN ORSHOVEN A, VAN DEN BERGHE H. About the t(8;13)(p11;q12) clinico-pathologic entity. Blood 1996;87:1658-1659.
3. STILL IH, CHERNOVA O, HURD D, STONE RM, COWELL JK. Molecular characterization of the t(8;13)(p11;q12) translocation associated with an atypical myeloproliferative disorder: evidence for three discrete loci involved in myeloid leukemias on 8p11. Blood 1997;90:3136-3141.
4. ROY S, SZER J, CAMPBELL LJ, JUNEJA S. Sequential transformation of t(8;13)-related disease. Acta Haematol 2002;107:95-97.
5. JABBARAL-OBAIDI M, RYMES N, WHITE P, POMFRET M, SMITH H, STARCZYNSKI J, JOHNSON R. A fourth case of 8p11 myeloproliferative disorder transforming to B-lineage acute lymphoblastic leukaemia. a case report. Acta Haematol 2002;107:98-100.
6. VIZMANOS JL, HERNÁNDEZ R, VIDAL MJ, LARRÁYOZ MJ, ODERO MD, MARÍN J, ARDANAZ MT, CALASANZ MJ, CROSS NCP. Clinical variability of patients with t(6;8)(q27;p12) and FGFR1OP-FGFR1 fusion: two further cases. Hematol J 2004;5:534-537.
7. GUASCH G, MACK GJ, POPOVICI C, DASTUGUE N, BIRNBAUM D, RATTNER JB, PÉBUSQUE MJ. FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33). Blood 2000;95:1788-1796.
8. FRIEDHOFF F, RAJENDRA B, MOODY R, ALAPATT T. Novel reciprocal translocation between chromosomes 8 and 9 found in a patient with myeloproliferative disorder. Cancer Genet Cytogenet 1983;9:391-394.
9. LEWIS JP, JENKS H, LAZERSON J. Philadelphia chromosome-negative chronic myelogenous leukemia in a child with t(8;9)(p11 or 12;q34). Am J Pediatr Hematol Oncol 1983;5:265-269.
10. OSCIER DG, MUFTI GJ, GARDINER A, HAMBLIN TJ. Reciprocal translocation between chromosomes 8 and 9 in atypical chronic myeloid leukaemia. J Med Genet 1985;22:398-401.
11. JOTTERAND BM, MÜHLEMATTER D, WICHT M, DELACRÉTAZ F, SCHMIDT PM. t(8;9)(p11;q32) in atypical chronic myeloid leukaemia: a new cytogenetic-clinicopathologic association? Br J Haematol 1992;81:307-309.
12. NAKAYAMA H, INAMITSU T, OHGA S, KAI T, SUDA M, MATSUZAKI A, UEDA K. Chronic myelomonocytic leukaemia with t(8;9)(p11;q34) in childhood: an example of the 8p11 myeloproliferative disorder? Br J Haematol 1996;92:692-695.
13. VAN DEN BERG H, KROES W, VAN DER SCHOOT CE, DEE R, PALS ST, BOUTS THM, SLATER RM. A young child with acquired t(8;9)(p11;q34): additional proof that 8p11 is involved in mixed myeloid/T lymphoid malignancies. Leukemia 1996;10:1252-1253.
14. SOHAL J, CHASE A, MOULD S, et al. Identification of four new translocations involving FGFR1 in myeloid disorders. Genes Chromosomes Cancer 2001;32:155-163.
15. LACOMBE F, DURRIEU F, BRIAIS A, DUMAIN P, BELLOC F, BASCANS E, REIFFERS J, BOISSEAU MR, BERNARD PH. Flow cytometry CD45 gating for immunophenotyping of acute myeloid leukemia. Leukemia 1997;11:1878-1886.
16. ISCN. In: MITELMAN F, ed. An international system for human cytogenetic nomenclature. Basel: S. Karger, 1995.
17. DISS TC, PENG H, WOTHERSPOON AC, ISAACSON PG, PAN L. Detection of monoclonality in low-grade B-cell lymphomas using the polymerase chain reaction is dependent on primer selection and lymphoma type. J Pathol 1993;169:291-295.
18. DISS TC, WATTS M, PAN LX, BURKE M, LINCH D, ISAACSON PG. The polymerase chain reaction in the demonstration of monoclonality in T cell lymphomas. J Clin Pathol 1995;48:1045-1050.
19. VAN DONGEN JJM, WOLVERS-TETTERO ILM. Analysis of immunoglobulin and T cell receptor genes. Clin Chim Acta 1991;198:1-92.
20. BELLONI E, TRUBIA M, GASPARINI P, et al. 8p11 myeloproliferative syndrome with a novel t(7;8) translocation leading to fusion of the FGFR1 and TIF1 genes. Genes Chromosomes Cancer 2005;42:320-325.