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Volumn 5, Issue 8, 2006, Pages 1905-1908

Little patients, losing patience: Pediatric cancer drug development

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CLOFARABINE;

EID: 33748349687     PISSN: 15357163     EISSN: None     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-06-0179     Document Type: Editorial
Times cited : (43)

References (18)
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    • Regulatory approvals of pediatric oncology drugs: Previous experience and new initiatives
    • Hirschfeld S, Ho PTC, Smith M, Pazdur R. Regulatory approvals of pediatric oncology drugs: previous experience and new initiatives. J Clin Oncol 2003;21:1066-73.
    • (2003) J Clin Oncol , vol.21 , pp. 1066-1073
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  • 2
    • 33748354063 scopus 로고    scopus 로고
    • Patient access to new therapeutic agents for pediatric cancer, December 2003: Report to Congress
    • Department of Health and Human Services, U.S. Food and Drug Administration. Washington (DC): Department of Health and Human Services, U.S. Food and Drug Administration
    • Department of Health and Human Services, U.S. Food and Drug Administration. Patient access to new therapeutic agents for pediatric cancer, December 2003: report to Congress. Washington (DC): Department of Health and Human Services, U.S. Food and Drug Administration; 2003.
    • (2003)
  • 4
    • 0037374498 scopus 로고    scopus 로고
    • The price of innovation: New estimates of drug development costs
    • DiMasi JA, Hansen RW, Grabowski HG. The price of innovation: new estimates of drug development costs. J Health Econ 2003;22: 151-85.
    • (2003) J Health Econ , vol.22 , pp. 151-185
    • DiMasi, J.A.1    Hansen, R.W.2    Grabowski, H.G.3
  • 5
    • 5044231070 scopus 로고    scopus 로고
    • Pharmaceutical industry profile, 2004
    • Pharmaceutical Research and Manufacturers of America (PhRMA). Washington (DC): Pharmaceutical Research and Manufacturers of America
    • Pharmaceutical Research and Manufacturers of America (PhRMA). Pharmaceutical industry profile, 2004. Washington (DC): Pharmaceutical Research and Manufacturers of America; 2004.
    • (2004)
  • 7
    • 84881270225 scopus 로고    scopus 로고
    • Drug research and children
    • U.S. Food and Drug Administration. FDA consumer magazine. Jan-Feb. Available from
    • Meadows M. Drug research and children. U.S. Food and Drug Administration. FDA consumer magazine. 2003 Jan-Feb. Available from: http://www.fda.gov/fdac/features/2003/103_drugs.html.
    • (2003)
    • Meadows, M.1
  • 8
    • 33748356500 scopus 로고    scopus 로고
    • History of pediatric studies, rule, legislation, and litigation
    • Biotechnology Industry Organization. Available from
    • Biotechnology Industry Organization. History of pediatric studies, rule, legislation, and litigation. Available from: http://www.bio.org/reg/ action/pedhist.asp?P=yes.
  • 9
    • 33748339822 scopus 로고    scopus 로고
    • Pediatric exclusivity statistics as of February 28, 2006
    • Food and Drug Administration. Available from
    • Food and Drug Administration. Pediatric exclusivity statistics as of February 28, 2006. Available from: http://www.fda.gov/cder/pediatric/ wrstats.htm.
  • 10
    • 33748365682 scopus 로고    scopus 로고
    • Cancer research funding
    • National Cancer Institute. National Cancer Institute Fact Sheet; Available from
    • National Cancer Institute. Cancer research funding. National Cancer Institute Fact Sheet; 2005. Available from: http://www.cancer.gov/ cancertopics/factsheet/NCI/research-funding.
    • (2005)
  • 11
    • 33748346675 scopus 로고    scopus 로고
    • National Cancer Institute. National Cancer Institute research on childhood cancers: Fact Sheet. National Cancer Institute Fact Sheet; Available from
    • National Cancer Institute. National Cancer Institute research on childhood cancers: Fact Sheet. National Cancer Institute Fact Sheet; 2005. Available from: http://www.cancer.gov/cancertopies/factsheet/ Sites-Types/childhood.
    • (2005)
  • 12
    • 33748362880 scopus 로고    scopus 로고
    • Survivors of childhood cancer and chronic illness
    • National Cancer Institute. Available from
    • National Cancer Institute. Survivors of childhood cancer and chronic illness; 2006. Available from: http://www.cancer.gov/cancertopics/coping/ childhood-cancer-survivor-study.
    • (2006)
  • 13
    • 33748362236 scopus 로고    scopus 로고
    • Late effects of treatment for childhood cancer
    • National Cancer Institute. Available from
    • National Cancer Institute. Late effects of treatment for childhood cancer; 2006. Available from: http://www.cancer.gov/cancertopics/pdq/ treatment/lateeffects/HealthProfessional/page2.
    • (2006)
  • 14
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    • Conquer Childhood Cancer Act, S. 2393/H.R. 4927
    • Conquer Childhood Cancer Act, S. 2393/H.R. 4927 (2006).
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  • 16
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    • Decision-making about research participation
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    • Assent Task Force, Children's Oncology Group. Decision-making about research participation. Available from: http://www.childrensoncologygroup.org/_files/COGAssentGuidelines.pdf.
  • 17
    • 77149179799 scopus 로고    scopus 로고
    • Surveillance Epidemiology and End Results (SEER) cancer statistics review, 1975-2002
    • Ries LAG, Eisner MP, Kosary CL, et al., editors. National Cancer Institute, Bethesda, MD. Available from: based on November 2004 SEER data submission, posted to the SEER Web site 2005
    • Ries LAG, Eisner MP, Kosary CL, et al., editors. Surveillance Epidemiology and End Results (SEER) cancer statistics review, 1975-2002, National Cancer Institute, Bethesda, MD. Available from: http://seer.cancer.gov/csr/1975_2002/, based on November 2004 SEER data submission, posted to the SEER Web site 2005.
  • 18
    • 0037089630 scopus 로고    scopus 로고
    • How sociodemographics, presence of oncology specialists, and hospital cancer programs affect accrual to cancer treatment trials
    • Sateren WB, Trimble EL, Abrams J, et al. How sociodemographics, presence of oncology specialists, and hospital cancer programs affect accrual to cancer treatment trials. J Clin Oncol 2002;20:2109-17.
    • (2002) J Clin Oncol , vol.20 , pp. 2109-2117
    • Sateren, W.B.1    Trimble, E.L.2    Abrams, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.