Engineered staphylococcal protein A's IgG-binding domain with cathepsin L inhibitory activity

Biochemical and Biophysical Research Communications

Volumn 349, Issue 1, 2006, Pages 449-453

  Bratkovič, Tomaž ^a,b   Berlec, Aleš ^c   Popovič, Tatjana ^c   Lunder, Mojca ^a   Kreft, Samo ^a   Urleb, Uroš ^b   Štrukelj, Borut ^a,c  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b Lek Pharmaceuticals   (Slovenia)

^c JO EF STEFAN INSTITUTE   (Slovenia)

Author keywords

Constrained loop; Cysteine proteases; Dual functionality; Inhibitory peptide; Protein scaffold; Staphylococcal protein A

Indexed keywords

CATHEPSIN L; CYSTEINE PROTEINASE; FC RECEPTOR; HYBRID PROTEIN; IMMUNOGLOBULIN G; PAPAIN; RECOMBINANT PROTEIN; SOLVENT; STAPHYLOCOCCUS PROTEIN A;

AMINO ACID SEQUENCE; ARTICLE; CIRCULAR DICHROISM; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN MODIFICATION; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATHEPSINS; CYSTEINE ENDOPEPTIDASES; DISULFIDES; IMMUNOGLOBULIN G; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; RABBITS; STAPHYLOCOCCAL PROTEIN A;

ORYCTOLAGUS CUNICULUS;

EID: 33748324648     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.08.078     Document Type: Article

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