Compact multileaf collimator for conformal and intensity modulated fast neutron therapy: Electromechanical design and validation

Medical Physics

Volumn 33, Issue 9, 2006, Pages 3313-3320

  Farr, J B ^a   Maughan, R L ^b   Yudelev, M ^c   Blosser, E ^d   Brandon, J ^d   Horste, T ^e   Forman, J D ^f  

^a Midwest Proton Radiotherapy Institute   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c WAYNE STATE UNIVERSITY   (United States)

^d MedCyc Corporation   (United States)

^e TD Engineering   (United States)

^f KARMANOS CANCER INSTITUTE   (United States)

Author keywords

Collimator; IMRT; MLC; Multileaf; Neutron

Indexed keywords

BIOMEDICAL ENGINEERING; NEUTRONS; PATIENT TREATMENT; REMOTE CONSOLES;

COLLIMATOR; ELECTRO MECHANICAL DESIGN; ELECTROMECHANICAL PROPERTY; FAST NEUTRON THERAPY; IMRT; MULTILEAF; MULTILEAF COLLIMATORS; THROUGHPUT CAPACITIES;

NEUTRON IRRADIATION;

TUNGSTEN;

ARTICLE; COLLIMATOR; COMPUTER AIDED DESIGN; COMPUTER ASSISTED RADIOTHERAPY; CYCLOTRON; GEOMETRY; HUMAN; INTENSITY MODULATED RADIATION THERAPY; NEUTRON THERAPY; PHYSICAL PERFORMANCE; PRIORITY JOURNAL; RADIATION BEAM; RADIATION DOSE; RADIATION EXPOSURE; VALIDATION PROCESS;

EID: 33748303076     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.2237506     Document Type: Article

References (16)

1. K. J. Russell, R. J. Caplan, G. E. Laramore, C. M. Burnison, M. H. Maor, M. E. Taylor, S. Zink, L. W. Davis, and T. W. Griffin, "Photon versus fast neutron external beam radiotherapy in the treatment of locally advanced prostate cancer: results of a randomized prospective trial," Int. J. Radiat. Oncol., Biol., Phys. 28, 47-54 (1994).
2. H. G. Blosser, W. E. Powers, R. L. Maughan, C. G. Orton, D. P. Ragan, G. F. Blosser, R. L. Burleigh, and E. B. Jemison, "Superconducting cyclotron facility for neutron therapy," in Proceedings of the Tenth International Conference on Cyclotrons, edited by F. Marti (IEEE, 1984), Vol. I(I), pp. 431-435.
3. H. G. Blosser, J. DeKamp, J. Griffin, D. Johnson, F. Marti, B. Milton, J. Vincent, G. Blosser, E. Jemison, R. Maughan, W. Powers, J. Purcell, and W. Young, "Compact superconducting cyclotron for neutron therapy," IEEE Trans. Nucl. Sci. NS-32, 3287-3391 (1985).
4. R. L. Maughan and W. E. Powers, "A superconducting cyclotron for neutron radiation therapy," Med. Phys. 21, 779-785 (1994).
5. R. L. Maughan and M. Yudelev, "Physical characteristics of a clinical d(48.5)+be neutron therapy beam produced by a superconducting cyclotron," Med. Phys. 22, 1459-1465 (1995).
6. R. L. Maughan, M. Yudelev, J. B. Farr, and J. D. Forman, "Status report for the Harper Hospital superconducting cyclotron neutron therapy facility," in Cyclotrons and Their Applications 2001, edited by F. Marti (AIP, Melville, New York, 2001), Vol. I(I), pp. 18-20.
7. J. D. Forman, M. Yudelev, S. Bolton, S. Tekyi-Mensah, and R. Maughan, "Fast neutron irradiation for prostate cancer," Cancer Metastasis Rev. 21, 131-135 (2002).
8. J. B. Farr, R. L. Maughan, M. Yudelev, J. D. Forman, E. J. Blosser, and T. Horste, "A multileaf collimator for neutron radiation therapy," in Cyclotrons and Their Applications 2001, edited by F. Marti (AIP, Melville, New York, 2001), Vol. I(I), pp. 154-156.
9. R. L. Maughan, M. Yudelev, A. Aref, P. J. Chuba, J. D. Forman, E. J. Blosser, and T. Horste, "Design considerations for a computer controlled multileaf collimator for the Harper Hospital fast neutron therapy facility," Med. Phys. 29, 499-508 (2002).
10. A. Brahme, J. Eenmaa, S. Lindbäck, A. Montelius, and P. Wootton, "Neutron beam characteristics from 50 MeV protons on beryllium using a continuously variable multi-leaf collimator," Radiother. Oncol. 1, 65-76 (1983).
11. R. L. Maughan, M. Yudelev, J. D. Forman, S. B. Williams, D. Gries, T. M. Fletcher, W. Chapman, E. J. Blosser, and T. Horste, "Attenuation and activation characteristics of steel and tungsten and the suitability of these materials for use in a fast neutron multileaf collimator," Med. Phys. 28, 1006-1009 (2001).
12. T. J. Jordan and P. C. Williams, "The design and performance characteristics of a multileaf collimator," Phys. Med. Biol. 39, 231-251 (1994).
13. R. L. Maughan and M. Yudelev, "A light localizer for use at large distances from a radiation source," Med. Phys. 25, 892-893 (1995).
14. D. W. Clegg and A. A. Collyer, Irradiation Effects on Polymers (Elsevier Applied Science, New York, 1991).
15. A. W. Chao and M. Tigner, Handbook of Accelerator Physics and Engineering (World Scientific, New Jersey, 1999).
16. R. L. Maughan, G. F. Blosser, E. B. Blosser, M. S. Yudelev, J. D. Forman, H. G. Blosser, and W. E. Powers, "A multirod collimator for neutron therapy," Int. J. Radiat. Oncol., Biol., Phys. 34, 411-420 (1996).