You say estren, I say estrogen. Let's call the whole replacement off!

Journal of Clinical Investigation

Volumn 116, Issue 9, 2006, Pages 2327-2329

  Neill, Ushma S ^a,b  

^a College of Physicians and Surgeons ^*  (United States)

^b Box 57A ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 ESTREN 3 ALPHA 17 BETA DIOL; ANABOLIC AGENT; ANDROGEN; ESTREN; ESTROGEN; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; UNCLASSIFIED DRUG;

BONE GROWTH; BONE MASS; CATABOLISM; CELL PROLIFERATION; DRUG BINDING; DRUG EFFECT; DRUG POTENCY; GENITAL SYSTEM; GONADECTOMY; HOMEOSTASIS; HYPERTROPHY; NONHUMAN; OSTEOPOROSIS; PRIORITY JOURNAL; REVIEW; SEMINAL VESICLE; UTERUS;

ANIMALS; BONE DENSITY; ESTRENES; ESTROGEN REPLACEMENT THERAPY; ESTROGENS; ESTRUS; FEMALE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; RECEPTORS, ANDROGEN; SELECTIVE ESTROGEN RECEPTOR MODULATORS;

EID: 33748302967     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI29733     Document Type: Review

References (7)

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2. Deroo, B.J., and Korach, K.S. 2006. Estrogen receptors and human disease. J. Clin. Invest. 116:561-570. doi:10.1172/JCI27987.
3. Kousteni, S., et al. 2002. Reversal of bone loss in mice by nongenotropic signaling of sex steroids. Science. 298:843-846.
4. Kousteni, S., et al. 2003. Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids. J. Clin. Invest. 111:1651-1664. doi:10.1172/JCI200317261.
5. Moverare, S., et al. 2003. Estren is a selective estrogen receptor modulator with transcriptional activity. Mol. Pharmacol. 64:1428-1433.
6. Hewitt, S.C., Collins, J., Grissom, S., Hamilton, K., and Korach, K.S. 2006. Estren behaves as a weak estrogen rather than a nongenomic selective activator in the mouse uterus. Endocrinology. 147:2203-2214.
7. Windahl, S.H., et al. 2006. Bone protection by estrens occurs through non-tissue-selective activation of the androgen receptor. J. Clin. Invest. 116:2500-2509. doi:10.1172/JCI28809.