DA-9601, Artemisia asiatica herbal extract, ameliorates airway inflammation of allergic asthma in mice

Molecules and Cells

Volumn 22, Issue 1, 2006, Pages 104-112

  Kim, Ji Young ^a   Kim, Dae Yong ^a   Lee, Yun Song ^a   Lee, Bong Ki ^b   Lee, Kyung Hoon ^a,c   Ro, Jai Youl ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

^c Samsung Medical Center   (South Korea)

Author keywords

Allergic asthma; CD40; CD40L; Goblet cells; IgE; MAP kinases; Matrix metalloproteinases (MMPs); NF B; VCAM 1

Indexed keywords

ANTIINFLAMMATORY AGENT; ARTEMISIA ASIATICA EXTRACT; CD40 ANTIGEN; CD40 LIGAND; CYTOKINE; DA 9601; IMMUNOGLOBULIN E; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRIX METALLOPROTEINASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; OVALBUMIN; PLANT EXTRACT; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTEMISIA; ARTEMISIA ASIATICA; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL MOBILITY SHIFT ASSAY; GOBLET CELL; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; LUNG LAVAGE; LUNG PARENCHYMA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROVOCATION TEST; RESPIRATORY TRACT INFLAMMATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ZYMOGRAPHY;

ADMINISTRATION, ORAL; ANIMALS; ANTI-ASTHMATIC AGENTS; ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD40; ARTEMISIA; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CD40 LIGAND; CYTOKINES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; LUNG; MAP KINASE KINASE 4; MICE; MICE, INBRED BALB C; NF-KAPPA B; OVALBUMIN; PLANT EXTRACTS; VASCULAR CELL ADHESION MOLECULE-1;

ARTEMISIA ASIATICA; CAVIA PORCELLUS;

EID: 33748289547     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Banchereau, J., Bazan, F., Blanchard, D., Briere, F., Galizzi, J. P., et al. (1994) The CD40 antigen and its ligand. Annu. Rev. Immunol. 12, 881-922.
2. Bond, M., Fabunmi, R. P., Baker, A. H., and Newby, A. C. (1998) Synergistic up-regulation of metalloproteinase-9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF-κB. FEBS Lett. 435, 29-34.
3. Bruce, C. and Thomas, P. S. (2005) The effect of marimastat, a metalloprotease inhibitor, on allergen-induced asthmatic hyper-reactivity. Toxicol. Appl. Pharmacol. 205, 126-132.
4. Bureau, F., Bonizzi, G., Kirschvink, N., Delhalle, S., Desmecht, D., et al. (2000) Correlation between nuclear factor-κB activity in bronchial brushing samples and lung dysfunction in an animal model of asthma. Am. J. Respi.r Crit. Care Med. 161, 1314-1321.
5. Burgess, J. K., Blake, A. E., Boustany, S., Johnson, P. R., Armour, C. L., et al. (2005) CD40 and OX40 ligand are increased on stimulated asthmatic airway smooth muscle. J. Allergy Clin. Immunol. 115, 302-308.
6. Chiappara, G., Gagliardo, R., Siena, A., Bonsignore, M. R., Bousquet, J., et al. (2001) Airway remodeling in the pathogenesis of asthma. Curr. Opin. Allergy Clin. Immunol. 1, 85-93.
7. Desmet, C., Gosset, P., Pajak, B., Cataldo, D., Bentires-Alj, M., et al. (2004) Selective blockade of NF-κB activity in airway immune cells inhibits the effector phase of experimental asthma. J. Immunol. 173, 5766-5775.
8. Edwan, J. H., Perry, G, Talmadge, J. E., and Agrawal, D. K. (2004) Fit-3 ligand reverses late allergic response and airway hyper-responsiveness in a mouse model of allergic inflammation. J. Immunol. 172, 5016-5023.
9. Finkelman, F. D., Yang, M., Perkins, C., Schleifer, K., Sproles, A., et al. (2005) Suppressive effect of IL-4 on IL-13-induced genes in mouse lung. J. Immunol. 174, 4630-4638.
10. Hahm, K. B., Oh, T. Y., Lee, J. S. Ahn, B. O., Lee, K. J., et al. (2001) Efficacy of combination treatment of antioxidant and acid suppression in the treatment of gastroesophageal reflux disease: Implication for the complete healing. Gut 49, 364-371.
11. Huh, K., Kwon, T. H., Shin, U. S., Kim, W. B., Ahn, B. O., et al. (2003) Inhibitory effect of DA-9601 on ethanol-induced gastrohemorrhagic lesion and gastric xanthine oxidase activity in rats. J. Ethnopharmacol. 88, 269-273.
12. Johnson, P. R., Burgess, J. K., Underwood, P. A., Au, W., Poniris, M. H., et al. (2004) Extracellular matrix proteins modulate asthmatic airway smooth muscle cell proliferation via an autocrine mechanism. J. Allergy Clin. Immunol. 113, 690-696.
13. Kawabe, T. (1994) The immune response in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. Immunity 1, 167-178.
14. Kim, J. Y., Kwon, E. Y., Lee, Y. S., Kim, W. B., and Ro, J. Y. (2005) Eupatilin blocks mediator release via tyrosine kinase inhibition in activated guinea pig lung mast cells. J. Toxicol. Environ. Health 68, 2060-2077.
15. Ko, F. W., Diba, C., Roth, M., McKay, K., Johnson, P. R., et al. (2005) A comparison of airway and serum matrix metalloproteinase-9 activity among normal subjects, asthmatic patients, and patients with asthmatic mucus hypersecretion. Chest 127, 1919-1927.
16. Kon, O. M. and Kay, A. B. (1999) T cells and chronic asthma. Int. Arch. Allergy Immunol. 118, 133-135.
17. Kumagai, K., Ohno, I., Okada, S., Ohkawara, Y., Suzuki, K., et al. (1999) Inhibition of matrix metalloproteinase prevents allergen-induced airway inflammation in a murine model of asthma. J. Immunol. 162, 4212-4219.
18. Lee, J. S., Oh, T. Y., Ahn, B. 0., Kim, W. B., Kim, Y. B., et al. (2001) Involvement of oxidative stress in experimentally induced reflux esophagitis and Barrett's esophagus: clue for chemoprevention by antioxidant treatment. Mutat. Res. 480-481, 189-200.
19. Lee, B. K., Yoo, J. E., Jang, Y. S., Kim, J. Y., Hong, C. S., et al. (2004a) Allergen-specific immunosuppression by ovalbumin fused with diphtheria toxin in mice sensitized with albumins of different origin. Clin. Exp. Allergy 34, 1642-1648.
20. Lee, Y. N., Tuckerman, J., Nechshtan, H., Schutz, G., Razin, E., et al. (2004b) c-Fos as a regulator of degranulation and cytokine production in Fcepsilon RI-activated mast cells. J. Immumol. 173, 2571-2577.
21. Lim, Y.-C., Garcia-Cardena, G., Allport, J. R., Zervoglos, M., Connolly, A. J., et al. (2003) Heterogeneity of endothelial cells from different organ sites in T-cell subset recruitment. Am. J. Pathol. 162, 1591-1601.
22. McKay, A., Leung, B. P., McInnes, I. B., Thomson, N. C., and Liew, F. Y. (2004) A novel anti-inflammatory role of simvastatin in a murine model of allergic asthma. J. Immunol. 172, 2903-2908.
23. McMillan, S. J., Kearley, J., Campbell, J. D., Zhu, X-W., Narbi, K. Y., et al. (2004) Matrix metalloproteinase-9 deficiency results in enhanced allergen-induced airway inflammation. J. Immunol. 172, 2586-2594.
24. Nagase, H. and Woessner, J. F. Jr. (1999) Matrix metalloproteinases. J. Biol. Chem. 274, 21491-21494.
25. Ohkawara, Y, Yamauchi, K., Maruyama, N., Hoshi, H., Ohno, I., et al. (1995) In situ expression of the cell adhesion molecules in bronchial tissues from asthmatics with air flow limitation: in vivo evidences VCAM-1/VLA-4 interaction in selective eosinophil infiltration. Am. J. Respir. Cell. Mol. Biol. 12, 4-12.
26. Picado, C., Bioque, G., Roca-Ferrer, J., Pujols, L., Mullol, J., et al. (2003) Nuclear factor-κB activity is down-regulated in nasal polyps from aspirin-sensitive asthmatics. Allergy 58, 122-126.
27. Renauld, J. C. (2001) New insights into the role of cytokines in asthma. J. Clin. Pathol. 54, 577-589.
28. Romagnani, S. (2001) Cytokines and chemoattractants in allergic inflammation. Mol. Immunol. 38, 881-885.
29. Ryzhov, S., Goldstein, A. E., Matafonov, A., Zeng, D., Biaggioni, I., et al. (2004) Adenosine-induce IgE synthesis by B lymphocytes: an A2B-medisted process involving Th2 cytokines IL-4 and IL-13 with implications for asthma. J. Immunol. 172, 7726-7733.
30. Seo, H. J. and Surh, Y. J. (2001) Eupatilin, a pharmacologically active flavone derived from Artemisia plants, induces apoptosis in human promyelocytic leukemia cells. Mutat. Res. 496, 191-198.
31. Steinke, J. W. and Borish, L. (2001) Th2 cytokines and asthma: Interleukin-4-its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists. Respir Res. 2, 66-70.
32. Wills-Karp, M. and Karp, C. L. (2004) Eosinophils in asthma: remodeling a tangled tale. Science 305, 1726-1729.
33. Yang, L., Cohn, L., Zhang, D. H., Homer, R., Ray, A., et al. (1998) Essential role of nuclear factor κB in the induction of eosinophilia in allergic airway inflammation. J. Exp. Med. 188, 1739-1750.
34. Zimmermann, N., Hershey, G. K., Foster, P. S., and Rothenberg, M. E. (2003) Chemokines in asthma: Cooperative interaction between chemokines and IL- 13. J A l1eqy Clin. Immunol. 111, 227-242.