Liquid injectable silicone: A review of its history, immunology, technical considerations, complications, and potential

Plastic and Reconstructive Surgery

Volumn 118, Issue 3 SUPPL., 2006, Pages

  Narins, Rhoda S ^a   Beer, Kenneth ^b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CORTICOSTEROID; CORTISONE; ETANERCEPT; HYALURONIC ACID; HYDROXYAPATITE; IMIQUIMOD; POLYLACTIC ACID; SILICONE; STEROID;

BACTERIAL INFECTION; BIOSAFETY; CELLULITIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; DEATH; ESTHETIC SURGERY; GRANULOMA; GRANULOMATOUS SKIN DISEASE; HIV ASSOCIATED LIPODYSTROPHY; HUMAN; IMPLANT; INJECTION; INJECTION SITE BLEEDING; INJECTION SITE CONTUSION; INJECTION SITE DISCOLORATION; INJECTION SITE EDEMA; INJECTION SITE ERYTHEMA; INJECTION SITE REACTION; INJECTION SITE SWELLING; INJECTION SITE ULCER; MIGRATION; NECROSIS; PANNICULITIS; PNEUMONIA; PRIORITY JOURNAL; REVIEW; SOFT TISSUE; TREATMENT CONTRAINDICATION; TREATMENT INDICATION;

ANIMALS; BIOCOMPATIBLE MATERIALS; CICATRIX; CLINICAL TRIALS, PHASE II; COSMETIC TECHNIQUES; DRUG HYPERSENSITIVITY; EDEMA; FEMALE; FOREIGN-BODY MIGRATION; GRANULOMA, FOREIGN-BODY; HIV-ASSOCIATED LIPODYSTROPHY SYNDROME; HUMANS; INJECTIONS, SUBCUTANEOUS; MALE; PATIENT SATISFACTION; REJUVENATION; SILICONES; SKIN AGING; TREATMENT OUTCOME;

EID: 33748267903     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.prs.0000234919.25096.67     Document Type: Review

References (44)

1. Orentreich, D., and Jones, D. Liquid injectable silicone. In Procedures in Cosmetic Dermatology: Soft Tissue Augmentation. New York: Elsevier, 2005. Pp. 77-91.
2. Duffy, D. Silicone granulomata management. Dermatol. Times May : 75, 2003.
3. Duffy, D. M. Silicone: A critical review. Adv. Dermatol. 5: 93, 1990.
4. Duffy, D. M. Tissue injectable liquid silicone: New perspectives. In A. Klein (Ed.), Augmentation in Clinical Practice: Procedures and Techniques. New York: Marcel Dekker, 1998. Pp. 237-263.
5. Duffy, D. Liquid silicone for soft tissue augmentation. J. Dermatol. Surg. 31: 1530, 2005.
6. Duffy, D. Silicone conundrum: A battle of anecdotes. Dermatol. Surg. 28: 590, 2002.
7. Duffy, D. Presentation AS 352. Silicone granulomas: Causation and treatment. Presented at the Annual Meeting of the American Society of Dermatologic Surgeons, New Orleans, La., October 11, 2003.
8. Duffy, D. Complications of fillers: An overview. J. Dermatol. Surg. 31: 1626, 2005.
9. Orentreich, D. S., and Orentriech, N. Subcutaneous incisionless (subcision) surgery for the correction of depressed scars and wrinkles. Dermatol. Surg. 21: 543, 1995.
10. Orentreich, D. S., and Orentreich, N. O. Injectable Fluid Silicone: Principles of Dermatologic Surgery. New York: Marcel Dekker, 1989. Pp. 1349-1395.
11. Orentreich, N. O. Soft Tissue Augmentation with Medical-Grade Fluid Silicone; Biomaterials in Reconstructive Surgery . St. Louis: Mosby, 1983. Pp. 859-881.
12. Orentreich, D. Liquid injectable silicone: Techniques for soft tissue augementation. Clin. Plast. Surg. 27: 595, 2000.
13. Selmanowitz, V. J., and Orentreich, N. O. Medical-grade fluid silicone: A monographic review. J. Dermatol. Surg. Oncol. 3: 595, 1977.
14. Orentreich, D. S., and Jones, D. H. Liquid injectable silicone. In J. Dover (Ed.), Procedures in Cosmetic Dermatology . Philadelphia: Elsevier Saunders, 2005. Pp. 77-91.
15. Balkin, S. W. Plantar keratoses: Treatment by injectable liquid silicone. Clin. Orthop. 87: 235, 1972.
16. Balkin, S. W. Treatment of painful scars on soles and digits with injection of fluid silicone. J. Dermatol. Surg. Oncol. 3: 612, 1977.
17. Balkin, S. W. Fluid silicone augmentation in the diabetic foot: A fifteen year study (scientific exhibit). Presented at the 1979 Annual Meeting of the American Diabetes Association, Los Angeles, Calif., June 9-12, 1979.
18. Balkin, S. W. The fluid silicone prosthesis. Clin. Podiatry 1: 145, 1984.
19. Balkin, S. W. Treatment of corns by injectable silicone. Arch. Dermatol. 3: 1143, 1975.
20. Balkin, S. W., and Kaplan, L. Injectable silicone and the diabetic foot: A 25-year report. Foot 2: 83.
21. Balkin, S. W. Fluid silicone implantation of the foot. In D. Lorimer (Ed.), Neale's Common Foot Disorders: Diagnosis and Management, 5th Ed. Edinburgh, U.K.: Churchill Livingstone, 1997. Pp. 387-400.
22. Wallace, W. D., Balkin, S. W., Kaplan, L., and Nelson, S. The histologic host response to liquid silicone injections for prevention of pressure-related ulcers of the foot: A 38-year study. J. Am. Podiatr. Med. Assoc. 94: 550, 2004.
23. Balkin, S. W. DPM injectable silicone and the foot: A 41-year clinical and histologic history. Dermatol. Surg. 31: 1557, 2005.
24. Council on Scientific Affairs, American Medical Association. Silicone gel breast implants. J.A.M.A . 270: 2602, 1993.
25. Frisch, E. E. Technology of silicones in biomedical applications. In L. Rubin (Ed.), Biomaterials in Reconstructive Surgery. St. Louis: Mosby, 1983. Pp. 73-90.
26. Rapaport, M., Vinnik, C., and Zarem, H. Injectable silicone: Cause of facial nodules, cellulitis, ulcerations and migration. Aesthetic Plast. Surg. 20: 267, 1996.
27. Kagan, H. D. Sakurai injectable silicone formula: A preliminary report. Arch. Otolaryngol. 78: 663, 1963.
28. Selmanowitz, V. J., and Orentreich, N. O. Medical-grade fluid silicone: A monographic review. J. Dermatol. Surg. Oncol. 3: 597, 1977.
29. Rees, T. D., Platt, J., and Ballantyne, D. L. An investigation of cutaneous response to dimethylpolysiloxane (silicone liquid) in animals and humans: A preliminary report. Plast. Reconstr. Surg. 35: 131, 1965.
30. Achauer, B. M. A serious complication following medical grade silicone injection of the face. Plast. Reconstr. Surg. 71: 251, 1983.
31. Mastruserio, D. N., Pesqueira, M. J., and Cobb, M .W. Severe granulomatous reaction and facial ulceration occurring after subcutaneous silicone injection. J. Am. Acad. Dermatol. 34: 849, 1996.
32. Jones, D., Carruthers, A., Orentreich, D., et al. Highly purified 1000 cst silicone oil for the treatment of human immunodeficiency virus associated facial lipoatrophy: An open pilot trial. Dermatol. Surg. 30: 1279, 2004.
33. Jones, D. Treatment options for HIV facial lipoatrophy. Dermatol. Surg. 31: 1519, .
34. Duffy, D. M. Tissue injectable liquid silicone: New perspectives. In A. Klein (Ed.), Liquid Silicone for Soft Tissue Augmentation: Histological, Clinical, and Molecular Perspectives. New York: Marcel Dekker, .
35. Fulton, J., Porumb, S., Caruso, J., and Shitabata, P. Lip augmentation with liquid silicone. Dermatol. Surg. 31: 1577, 2005.
36. Rapaport, M. J. Silicone redux: Caution. Presented at the 61st Annual Meeting of the American Academy of Dermatology, San Francisco, Calif., March 21, 2003.
37. Bigata, X., Ribera, M., Bielsa, I., and Ferrandiz, C. Adverse granulomatous reaction after cosmetic dermal silicone injection. Dermatol. Surg. 27: 198, 2001.
38. Bauman, L., and Halem, M. Lip silicone granulomatous foreign body reaction treated with Aldara (imiquimod 5%). Dermatol. Surg. 29: 429, 2003.
39. Gurvits, G. Silicone pneumonitis after a cosmetic augmentation procedure. N. Engl. J. Med. 354: 211, 2006.
40. Winer, L. H., Sternberg, T. H., Herman, R., et al. Tissue reactions to injected silicone liquids. Arch. Dermatol. 90: 588, 1964.
41. Fox, L. P., Geyer, A. S., Husain, S., Della-Latta, P., and Grossman, M. E. Mycobacterium abscessus cellulitis and multifocal abscesses of the breasts in a transsexual from illicit intramammary injections of silicone. J. Am. Acad. Dermatol. 50: 450, 2004.
42. Yee, A., and Pochapin, M. Treatment of complicated sarcoidosis with Infliximab anti-tumor necrosis factor-alpha therapy. Ann. Intern. Med. 135: 27, 2001.
43. Bondurant, S., Ernster, V., and Herdman, R. (Eds.). Safety of Silicone Breast Implants . Washington, D.C.: Institute of Medicine, National Academy of Sciences, National Academy Press, 2000. Pp. 22, 146, 241, 247, 112, 169, 182, 183, 186, 191.
44. Angell, M. Science on Trial. New York: W.W. Norton, 1996.