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Volumn 34, Issue 20, 1995, Pages 2289-2291

Radiofrequency Encoded Combinatorial Chemistry

Author keywords

combinatorial chemistry; microreactors; peptides; radiofrequency encoding

Indexed keywords


EID: 33748243831     PISSN: 05700833     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.199522891     Document Type: Article
Times cited : (309)

References (36)
  • 8
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    • Die Medizinische Chemie im Goldenen Zeitalter der Biologie: Lehren aus der Steroid- und Peptidforschung
    • (1991) Angewandte Chemie , vol.103 , pp. 1305
    • Hirschmann, R.1
  • 33
    • 84985583088 scopus 로고    scopus 로고
    • Encoding and decoding was accomplished using radiofrequency pulse signals (100–400 kHz) whose generation, transmission, and retrieval was assisted by appropriate computer hardware and software.
  • 34
    • 0028135116 scopus 로고
    • The number selected for the construction of this combinatorial library was chosen to virtually ensure the statistical formation of a 24‐member library, see:,. Of course, sorting out the Microreactors precisely prior to each “split” converts this statistical method into an exact approach with one compound per Microreactor
    • (1994) J. Med. Chem. , vol.37 , pp. 2985
    • Burgess, K.1    Liaw, A.I.2    Wang, N.3
  • 35
    • 84985583084 scopus 로고    scopus 로고
    • 3).
  • 36
    • 84985551905 scopus 로고    scopus 로고
    • The SMART chips are equipped with a standard EEPROM (Electrically Erasable, Programmable, Read‐Only Memory) unit and temperature‐sensing probe; they are passive devices deriving their required energy directly from the radiofrequency pulses used for encoding. These devices are enclosed in glass and are therefore completely inert to most reagents and conditions used in organic synthesis and can withstand temperatures between −78 °C and 150 °C. These devices will be available from IRORI Quantum Microchemistry.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.