Persistent joint swelling and borrelia-specific antibodies in Borrelia garinii-infected mice after eradication of vegetative spirochetes with antibiotic treatment

Microbes and Infection

Volumn 8, Issue 8, 2006, Pages 2044-2051

  Yrjänäinen, Heta ^a   Hytönen, Jukka ^a   Söderström, Karl Ove ^a   Oksi, Jarmo ^a   Hartiala, Kaija ^a   Viljanen, Matti K ^a  

^a UNIVERSITY OF TURKU   (Finland)

Author keywords

Antibiotics; Borrelia garinii; Mouse

Indexed keywords

A PEN; AMPICILLIN; CEFTRIAXONE; IMMUNOGLOBULIN G ANTIBODY; ROCEPHALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ANTIBODY TITER; ARTICLE; BORRELIA GARINII; BORRELIA INFECTION; CONTROLLED STUDY; FEMALE; FOLLOW UP; HISTOPATHOLOGY; JOINT SWELLING; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PERSISTENT INFECTION; PRIORITY JOURNAL; SPIROCHETE; TREATMENT OUTCOME;

ACHILLES TENDON; AMPICILLIN; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBODIES, BACTERIAL; BORRELIA BURGDORFERI GROUP; CEFTRIAXONE; DISEASE MODELS, ANIMAL; FEMALE; HISTOCYTOCHEMISTRY; IMMUNOGLOBULIN G; JOINT DISEASES; JOINTS; LYME DISEASE; LYMPHOCYTES; MICE; MICE, INBRED C3H; SYNOVIAL MEMBRANE;

ANIMALIA; BORRELIA; BORRELIA GARINII; SPIROCHAETALES;

EID: 33748206687     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2006.03.008     Document Type: Article

References (30)

1. Steere A.C. Lyme disease. N. Engl. J. Med 321 (1989) 586-596
2. Baranton G., Postic D., Saint Girons I., Boerlin P., Piffaretti J.C., Assous M., and Grimont P.A. Delineation of Borrelia burgdorferi sensu stricto, Borrelia garinii sp. nov., and group VS461 associated with Lyme borreliosis. Int. J. Syst. Bacteriol. 42 (1992) 378-383
3. Lane R.S., Piesman J., and Burgdorfer W. Lyme borreliosis: relation of its causative agent to its vectors and hosts in North America and Europe. Annu. Rev. Entomol. 36 (1991) 587-609
4. Steere A.C., and Malawista S.E. Cases of Lyme disease in the United States: locations correlated with distribution of Ixodes dammini. Ann. Intern. Med. 91 (1979) 730-733
5. Steere A.C., Schoen R.T., and Taylor E. The clinical evolution of Lyme arthritis. Ann. Intern. Med. 107 (1987) 725-731
6. Balmelli T., and Piffaretti J.C. Association between different clinical manifestations of Lyme disease and different species of Borrelia burgdorferi sensu lato. Res. Microbiol. 146 (1995) 329-340
7. van Dam A.P., Kuiper H., Vos K., Widjojokusumo A., de Jongh B.M., Spanjaard L., Ramselaar A.C., et al. Different genospecies of Borrelia burgdorferi are associated with distinct clinical manifestations of Lyme borreliosis. Clin. Infect. Dis. 17 (1993) 708-717
8. Steere A.C., Hutchinson G.J., Rahn D.W., Sigal L.H., Craft J.E., DeSanna E.T., and Malawista S.E. Treatment of the early manifestations of Lyme disease. Ann. Intern. Med. 99 (1983) 22-26
9. Steere A.C. Lyme disease. N. Engl. J. Med 345 (2001) 115-125
10. Weinstein A., and Britchkov M. Lyme arthritis and post-Lyme disease syndrome. Curr. Opin. Rheumatol. 14 (2002) 383-387
11. Barthold S.W., Beck D.S., Hansen G.M., Terwilliger G.A., and Moody K.D. Lyme borreliosis in selected strains and ages of laboratory mice. J. Infect. Dis. 162 (1990) 133-138
12. Barthold S.W., de Souza M.S., Janotka J.L., Smith A.L., and Persing D.H. Chronic Lyme borreliosis in the laboratory mouse. Am. J. Pathol. 143 (1993) 959-971
13. Johnson R.C., Kodner C., and Russell M. In vitro and in vivo susceptibility of the Lyme disease spirochete, Borrelia burgdorferi, to four antimicrobial agents. Antimicrob. Agents Chemother. 31 (1987) 164-167
14. Moody K.D., Adams R.L., and Barthold S.W. Effectiveness of antimicrobial treatment against Borrelia burgdorferi infection in mice. Antimicrob. Agents Chemother. 38 (1994) 1567-1572
15. Oteo J.A., Backenson P.B., M del V., Garcia Monco J.C., Rodriguez I., Escudero R., and Anda P. Use of the C3H/He Lyme disease mouse model for the recovery of a Spanish isolate of Borrelia garinii from erythema migrans lesions. Res. Microbiol. 149 (1998) 39-46
16. Pachner A.R., Dail D., Bai Y., Sondey M., Pak L., Narayan K., and Cadavid D. Genotype determines phenotype in experimental Lyme borreliosis. Ann. Neurol. 56 (2004) 361-370
17. Lawrenz M.B., Wooten R.M., Zachary J.F., Drouin S.M., Weis J.J., Wetsel R.A., and Norris S.J. Effect of complement component C3 deficiency on experimental Lyme borreliosis in mice. Infect. Immun. 71 (2003) 4432-4440
18. Suhonen J., Hartiala K., Tuominen-Gustafsson H., and Viljanen M.K. Sublethal concentrations of complement can effectively opsonize Borrelia burgdorferi. Scand. J. Immunol. 56 (2002) 554-560
19. Viljanen M.K., and Punnonen J. The effect of storage of antigen-coated polystyrene microwells on the detection of antibodies against Borrelia burgdorferi by enzyme immunoassay (EIA). J. Immunol. Methods 124 (1989) 137-141
20. Lim L.C., England D.M., DuChateau B.K., Glowacki N.J., Creson J.R., Lovrich S.D., Callister S.M., et al. Development of destructive arthritis in vaccinated hamsters challenged with Borrelia burgdorferi. Infect. Immun. 62 (1994) 2825-2833
21. Christopherson J.A., Munson E.L., England D.M., Croke C.L., Remington M.C., Molitor M.L., DeCoster D.J., et al. Destructive arthritis in vaccinated interferon gamma-deficient mice challenged with Borrelia burgdorferi: modulation by tumor necrosis factor alpha. Clin. Diagn. Lab. Immunol. 10 (2003) 44-52
22. Schaible U.E., Gay S., Museteanu C., Kramer M.D., Zimmer G., Eichmann K., Museteanu U., et al. Lyme borreliosis in the severe combined immunodeficiency (scid) mouse manifests predominantly in the joints, heart, and liver. Am. J. Pathol. 137 (1990) 811-820
23. Eiffert H., Karsten A., Thomssen R., and Christen H.J. Characterization of Borrelia burgdorferi strains in Lyme arthritis. Scand. J. Infect. Dis. 30 (1998) 265-268
24. Limbach F.X., Jaulhac B., Puechal X., Monteil H., Kuntz J.L., Piemont Y., and Sibilia J. Treatment resistant Lyme arthritis caused by Borrelia garinii. Ann. Rheum. Dis. 60 (2001) 284-286
25. Ma Y., Seiler K.P., Eichwald E.J., Weis J.H., Teuscher C., and Weis J.J. Distinct characteristics of resistance to Borrelia burgdorferi-induced arthritis in C57BL/6N mice. Infect. Immun. 66 (1998) 161-168
26. Coburn J., Medrano M., and Cugini C. Borrelia burgdorferi and its tropisms for adhesion molecules in the joint. Curr. Opin. Rheumatol. 14 (2002) 394-398
27. Kalish R.A., McHugh G., Granquist J., Shea B., Ruthazer R., and Steere A.C. Persistence of immunoglobulin M or immunoglobulin G antibody responses to Borrelia burgdorferi 10-20 years after active Lyme disease. Clin. Infect. Dis. 33 (2001) 780-785
28. Nowakowski J., Nadelman R.B., Sell R., McKenna D., Cavaliere L.F., Holmgren D., Gaidici A., et al. Long-term follow-up of patients with culture-confirmed Lyme disease. Am. J. Med. 115 (2003) 91-96
29. Bockenstedt L.K., Mao J., Hodzic E., Barthold S.W., and Fish D. Detection of attenuated, noninfectious spirochetes in Borrelia burgdorferi-infected mice after antibiotic treatment. J. Infect. Dis. 186 (2002) 1430-1437
30. Steere A.C., and Glickstein L. Elucidation of Lyme arthritis. Nat. Rev. Immunol. 4 (2004) 143-152