The human erythrocyte has developed the biconcave disc shape to optimise the flow properties of the blood in the large vessels

Medical Hypotheses

Volumn 67, Issue 5, 2006, Pages 1159-1163

  Uzoigwe, Chika ^a  

^a LEICESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; ATHEROGENESIS; BLOOD FLOW; BLOOD VOLUME; BRAIN BLOOD VESSEL; CARDIOVASCULAR DISEASE; CARDIOVASCULAR SYSTEM; ERYTHROCYTE; ERYTHROCYTE DISORDER; HEART HEMODYNAMICS; HUMAN; LAMINAR FLOW; MICROVASCULATURE; PRIORITY JOURNAL; TARGET CELL;

ATHEROSCLEROSIS; BLOOD FLOW VELOCITY; BLOOD VESSELS; BLOOD VOLUME; CAPILLARIES; CELL SHAPE; ERYTHROCYTES; HUMANS; MODELS, BIOLOGICAL; PRESSURE;

EID: 33748182826     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2004.11.047     Document Type: Article

References (13)

1. Branemark P.I., and Lindstrom J. The shape of circulating blood corpuscles. Biorheology 1 (1963) 139
2. Guest M.M., Bond T.P., Cooper R.G., and Derrick J.R. Red blood cells: change in capillaries. Science 142 (1963) 1319-1321
3. Yoshizumi M., Abe J., Tsuchiya K., Berk B.C., and Tamaki T. Stress and vascular responses: atheroprotective effect of laminar fluid shear stress in endothelial cells: possible and mitogen-activated protein kinases. J Pharmacol Sci 91 (2003) 172-176
4. Schilling R.F. Spherocytosis splenectomy strokes and heart attacks. Lancet 350 (1997) 1677-1678
5. Robinnette C.D., and Fraumeni Jr. J.F. Splenectomy and subsequent mortality in veterans of the 1939-1945 war. Lancet ii (1977) 127-129
6. 2 the shape of the erythrocyte. Mathematical and computer modelling 28 (1998) 73-77
7. Grebe R., and Zuckerman M.J. Erythrocyte shape stimulation by numerical optimisation. Biorheology 27 (1990) 735-746
8. Kádár A., and Glasz T. Development of atherosclerosis and plaque biology. Cardiovasc Surg 9 (2001) 109-121
9. Harvey J. Atlas of veterinary hematology: blood and bone marrow of domestic animals (2001), W.B. Saunders Company, Philadelphia p. 33
10. Fudge A.M. Laboratory medicine - avian and exotic pets (2000), W.B. Saunders Company, Philadelphia p. 15, 194
11. Kannel W.B. Current status of the epidemiology of brain infarction associated with occlusive disease. Stroke 2 (1971) 295-318
12. Wang C., and Schilling R.F. Myocardial infarction and thalassemia trait: an example of heterozygote advantage. Am J Hematol 49 (1995) 73-75
13. van Hilten J.J., Haan J., and Wintzen A.R. Cerebral infarction in hereditary spherocytosis. Stroke 20 (1989) 1755-1756