From clinical trials to clinical practice: Why the gap?

Hypertension

Volumn 48, Issue 2, 2006, Pages 196-197

  Kotchen, Theodore A ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMLODIPINE; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CHLORTALIDONE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DOXAZOSIN; LISINOPRIL; THIAZIDE DIURETIC AGENT;

CLINICAL PRACTICE; CLINICAL TRIAL; EDITORIAL; HUMAN; HYPERTENSION; PRIORITY JOURNAL;

ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; DIFFUSION OF INNOVATION; DIURETICS; DRUG UTILIZATION; HUMANS; HYPERTENSION; PHYSICIAN'S PRACTICE PATTERNS; RANDOMIZED CONTROLLED TRIALS; TREATMENT OUTCOME; UNITED STATES;

EID: 33748169331     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000229712.18111.b3     Document Type: Editorial

References (18)

1. Hajjar I, Kotchen TA. Trends in prevalence, awareness, treatment, and control of hypertension in the United States, 1988-2000. JAMA. 2003;290:199-206.
2. Lenfant C. Clinical research to clinical practice - lost in translation? N Engl J Med. 2003;349:868-874.
3. Berwick DM. Disseminating innovations in health care. JAMA. 1003;289:1969-1975.
4. Stafford RS, Monti V, Furberg CD, Ma J. Long-term and short-term changes in antihypertensive prescribing by office-based physicians in the United States Hypertension. 2006;48:213-218.
5. The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major cardiovascular events in hypertensive patients randomized to doxazosin vs. chlorthalidone: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attach Trial (ALLHAT). JAMA. 2000;283:1967-1975.
6. The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs. diuretic: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA. 2002;288:2981-2997.
7. Mancia G. Role of outcome trials in providing information on antihypertensive treatment; importance and limitations. Amer J Hyperten. 2006;19:1-7.
8. Siegel D, Lopez J. Trends in antihypertensive drug use in the United States: do the JNC V recommendations affect prescribing? JAMA. 1997;278:1745-1748.
9. Nelson CR, Knapp DA. Trends in antihypertensive drug therapy of ambulatory patients by US office-based physicians. Hypertension. 2000;36:600-603.
10. Guo JD, Liu GG, Christensen DB. How well have practices followed guidelines in prescribing antihypertensive drugs: the role of health insurance. Value in Health. 2003;6:18-28.
11. Rosenthal MB, Berndt ER, Donohue JM, Frank RG, Epstein AM. Promotion of prescription drugs to consumers. N Engl J Med. 2002;346:498-505.
12. Saul S. Doctors object as drug makers learn who's prescribing what. New York Times. May 4, 2006:A1.
13. Verdecchia P, Reboldi G, Angeli F, Gattobigio R, Bentivoglio M, Thijs L, Staessen JA, Porcellati C. Angiotensin-converting enzyme inhibitors and calcium channel blockers for coronary heart disease and stroke prevention. Hypertension. 2005;46:386-392.
14. Messerli FH. ALLHAT, or the soft science of the secondary end point. Ann Intern Med. 2003;139:777-780.
15. Wing LMH, Reid CM, Ryan P, Beilin LJ, Brown KA, Jennings GLR, Johnston CI, McNeil JJ, Macdonald GJ, Marley JE, Morgan TO, West MJ for the Second Australian National Blood Pressure Study Group. Comparison of outcomes with angiotensin-converting-enzyme inhibitors and diuretic for hypertension in the elderly. N Engl J Med. 2003;348:583-592.
16. Law MR, Wald NJ, Morris JK, Jordan RE. Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials. BMJ. 2003;326:1427-1434.
17. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, Jones DW, Materson BJ, Oparil S, Wright JT, Roccella EJ, and the National High Blood Pressure Education Program Coordinating Committee. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension. 2003;42:1206-1252.
18. Gu Q, Paulose-Rain R, Dillon C, Bart V. Antihyperetensive drug use among US adults with hypertension. Circulation. 2006;113:213-221.