Advances in pediatric growth hormone therapy: IGF-I-based dosing

Indian Pediatrics

Volumn 43, Issue 7, 2006, Pages 577-581

  Pawlikowska Haddal, Anna ^a   Cohen, Pinchas ^a  

^a MATTEL CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN GROWTH HORMONE; PLACEBO; SOMATOMEDIN C;

BODY COMPOSITION; CHILD GROWTH; CHRONIC KIDNEY FAILURE; CLINICAL TRIAL; DOSE RESPONSE; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG SAFETY; ENDOCRINE DISEASE; GROWTH HORMONE DEFICIENCY; HORMONAL THERAPY; HUMAN; IDIOPATHIC DISEASE; MEDICAL SPECIALIST; PATIENT MONITORING; PRADER WILLI SYNDROME; PROTEIN BLOOD LEVEL; REVIEW; SHORT STATURE; SMALL FOR DATE INFANT; TREATMENT OUTCOME; TREATMENT RESPONSE; TURNER SYNDROME; UNSPECIFIED SIDE EFFECT;

BODY HEIGHT; CHILD; DRUG MONITORING; GROWTH DISORDERS; HUMAN GROWTH HORMONE; HUMANS; INJECTIONS, SUBCUTANEOUS; INSULIN-LIKE GROWTH FACTOR I; SAFETY;

EID: 33748151436     PISSN: 00196061     EISSN: 00196061     Source Type: Journal    
DOI: None     Document Type: Review

References (13)

1. Rogol AD, Blethen SL, Sy JP, Veldhuis JD. Do growth hormone serial sampling, insulin-like growth factor-I (IGF-I) or auxological measurements have an advantage over GH stimulation testing in predicting the linear response to GH therapy? Clin Endocrinol (Oxf) 2003; 58: 229-237.
2. Hintz RL, Attie KM, Baptista J, Roche A. Effect of growth hormone treatment on adult height of children with idiopathic short stature. N Engl J Med 1999; 340: 502-507.
3. Leschek EW, Rose SR, Yanovski JA, Troendle JF, Quigley CA, Chipman JJ, et al. Effect of growth hormone treatment on adult height in peripubertal children with idiopathic short stature: A randomized, double-blind, placebo-controlled trial. J Clin Endocrinol Metab. 2004; 89: 3140-3148.
4. Finkelstein BS, Imperiale TF, Speroff T, Marrero U, Radcliffe DJ, Cuttler L. Effect of growth hormone therapy on height in children with idiopathic short stature. Arch Pediatr Adolesc Med 2002; 156: 230-240.
5. Cohen P, Bright GM, Rogol AD, Kappelgaard A, Rosenfeld RG. Effects of dose and gender on the growth and growth factor response to GH in GH-deficient children: Implications for efficacy and safety. J Clin Endocrinol Metab 2002; 87: 90-98.
6. Mauras N, Attie KM, Reiter EO, Saenger P, Baptista J. High-dose recombinant human growth hormone treatment of GH-deficient patients in puberty increases near-final height: A randomized, multicenter trial. J Clin Endocrinol Metab 2000; 85: 3653-3660.
7. van Teunenbroek A, de Muinck Keizer-Schrama SM, Stijnen T, Jansen M, Otten BJ, Delemarre-van de Waal HA, et al. Yearly stepwise increments of the growth hormone dose results in a better growth response after four years in girls with Turner syndrome. J Clin Endocrinol Metab 1996; 81: 4013-4021.
8. Kamp GA, Zwinderman AH, Van Doorn J, Hackeng W, Frolich M, Schonau E, et al. Biochemical markers of growth hormone sensitivity in children with idiopathic short stature: Individual capacity of IGF-I generation after high-dose GH treatment determines the growth response to GH. Clin Endocrinol 57: 315-325.
9. Park P, Cohen P. The role of insulin-like growth factor I monitoring in growth hormone-treated children. Horm Res 2004; 62: 59-65.
10. Colao A, Cuocolo A, Marzullo P, Nicolai E, Ferone D, Della Morte AM, et al. Is the acromegalic cardiomyopathy reversible? Effect of 5-year normalization of growth hormone and insulin-like growth factor I levels in cardiac performance. J Clin Endocrinol Metab 2001; 86: 1551-1557.
11. Cohen P, Clemmons DR, Rosenfeld RG. Does the GH-IGF axis play a role in cancer pathogenesis? Growth Horm IGF Res 2000; 10: 297-305.
12. Jenkins PJ, Bustin SA. Evidence for a link between IGF-I and cancer. Eur J Endocrinol 2004; 151: S17-22.
13. Ali O, Cohen P. Insulin-like growth factors and their binding proteins in children born small for gestational age: Implications for growth hormone therapy. Horm Res 2003; 60 : 115-123.