Effect of dietary apigenin on colonic ornithine decarboxylase activity, aberrant crypt foci formation, and tumorigenesis in different experimental models

Nutrition and Cancer

Volumn 54, Issue 2, 2006, Pages 243-251

  Au, Angela ^a,b   Li, Boyong ^c   Wang, Weiqun ^a,e   Roy, Hemant ^c,d,f   Koehler, Ken ^b   Birt, Diane ^a,c  

^a IOWA STATE UNIVERSITY   (United States)

^b Department of Statistics Center for Statistics and Applications in Forensic Evidence Iowa State University 2438 Osborn Dr Ames   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^d UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^e KANSAS STATE UNIVERSITY   (United States)

^f EVANSTON NORTHWESTERN HEALTHCARE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APIGENIN; AZOXYMETHANE; FLAVONOID; ORNITHINE DECARBOXYLASE; ORNITHINE DECARBOXYLASE INHIBITOR;

ABERRANT CRYPT FOCI; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER MODEL; CANCER PREVENTION; CELL STRAIN CACO 2; CHEMICAL CARCINOGENESIS; COLON CANCER; COLON CARCINOGENESIS; COLON MUCOSA; CONTROLLED STUDY; DIETARY INTAKE; ENZYME ACTIVITY; ENZYME INHIBITION; EXPERIMENTAL MODEL; FEMALE; FOOD INTAKE; GENE MUTATION; HUMAN; HUMAN CELL; INTESTINE CRYPT; MOUSE; NONHUMAN; STATISTICAL SIGNIFICANCE;

ANIMALS; APIGENIN; AZOXYMETHANE; CACO-2 CELLS; CARCINOGENS; COLON; COLONIC NEOPLASMS; DIET; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; MICE; MICE, INBRED STRAINS; ORNITHINE DECARBOXYLASE; PRECANCEROUS CONDITIONS; RANDOM ALLOCATION;

EID: 33748150062     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1207/s15327914nc5402_11     Document Type: Article

References (28)

1. Dashwood RH: Early detection and prevention of colorectal cancer (Review). Oncol Rep 6, 277-281, 1999.
2. World Cancer Research Fund/American Institute fOr Cancer Research: Food, Nutrition and the Prevention of Cancer: a global perspective. American Institute for Cancer Research, Washington, DC. 1997.
3. Hill JM: Mechanisms of diet and colon carcinogenesis. Eur J Cancer Prev 8, S95-S98, 1999.
4. Birt DF, Hendrich S, and Wang W: Dietary agents in caner prevention: flavonoids and isoflavonoids. Pharmacol Ther 90, 157-177, 2001.
5. Slattery ML, Potter JD, Coates A, Ma K-N, Berry TD, et al.: Plant foods and colon cancer: an assessment of specific foods and their related nutrients (United States). Cancer Causes Control 8, 575-590, 1997.
6. Birt DF and Bresnick E: Chemoprevention by nonnutrient components of vegetables and fruits. In: Human Nutrition: A Comprehensive Treatise. Alfin-Slater R and Kritchevsky D (eds.). New York: Plenum, 1991, pp 221-261.
7. Birt DF, Walker B, Tibbles MG, and Bresnick E: Anti-mutagenesis and anti-promotion by apigenin, robinetin and indole-3-carbinol. Carcinogenesis 7, 959-963, 1986.
8. Hertog MG, Hollman PC, and Katan MB: Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in lhe Netherlands. J Agric food Chem 40, 2379-2383, 1992.
9. Wei H, Tye L, Bresnick F, and Birt DF: Inhibitory effect of apigenin, a plant flavonoid, on epidermal ornithine decarboxylase and skin tumor promotion in mice. Cancer Res 50, 499-502, 1990.
10. Lepley DM, Li B, Birt DF, and Pelling JC: The chemopreventive flavonoid apigenin induces G2/M arrest in keratinocytes. Carcinogenesis 17, 2367-2375, 1996.
11. Wang W, Heideman L, Chung CS, Pelling JC, Kochler KJ, et al.: Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines. Mol Carcinog 28, 102-110, 2000.
12. Reddy BS, Nayini J, Tokumo K, Rigotty J, Zang E, et al.: Chemoprevention of colon carcinogenesis by concurrent administration of piroxicam, a nonsteroidal anti-inflammatory drug with D,L-a -difluoromethylomithine, and ornithine decarboxylase inhibitor, in diet. Cancer Res 50, 2562-2568, 1990.
13. Bird RP: Observation and quantification of aberrant crypts in the murine colon treated with a colon carcinogen-preliminary findings. Cancer Lett 37, 147-151, 1987.
14. Pretlow TP, Barrow BJ, Ashton WS, O'Riordan MA, Pretlow TG, et al.: Aberrant crypts: putative preneoplastic foci in human colonic mucosa. Cancer Res 51, 1564-1567, 1991.
15. Kinzler KW and Vogelstein B: Lessons from hereditary colon cancer. DisColon Rectum 87, 159-170, 1996.
16. Iwao K, Nakamori S, Kameyama M, Imok A, Kinoahir M, et al.: Activation of the beta-catenin gene by interstitial deletions involving exon 3 in primary colorectal carcinomas without adenomatous polyposis coli mutations. Cancer Res 58, 1021-1026, 1998.
17. Shoemaker AR, Gould KA, Luongo C, Moser AR, and Dove WF: Studies of neoplasia in the Min mouse. Biochim Biophys Acta 1332, F25-F48, 1997.
18. Yu C and Wang J: Mutation of APC gene in sporadic colorectal tumors. Zhonghua Zhong Liu Za Zhi 20, 348-350, 1998.
19. Jacoby RF, Llor X, Teng BB, Davidson NO, and Brasitus TA: Mutations in the K-ras oncogene induced by 1, 2-dimenthylhydrazine in the prencoplastic and neoplastic rat colonic mucosa. J Clin Invest 87, 624-30, 1991.
20. Birt DF, Duysen E, Wang WQ, and Yaktine A: Corticosterone supplementation reduced selective protein kinase C isoform expression in the epidermis of adrenalectomized mice. Cancer Epidem Biomarkers Prev 10, 679-685, 2001.
21. James JT, Shamsuddin AM, and Trump BF: Comparative study of the morphologic, histochemical, and proliferative changes induced in the large intestine of ICR/Ha and C57BL/Ha mice by 1,2-dimethylhydrazine. J Natl Cancer Inst 71, 955-964, 1983.
22. Paganelli GM, Saccoccio G, Brandi G, Bellentani S, Santucci R, et al.: Correlation between bromodeoxyuridine labeling and omithine decarboxylase levels in normal rectal mucosa of patients with colorectal adenoma. Cancer Lett 59, 221-224, 1991.
23. Bird RP: Role of aberrant crypt foci in understanding the pathogenesis of colon cancer. Canter Lett 93, 55-71, 1995.
24. Corpet DE and Taché S: Most effective colon cancer chemopreventive agents in rats: a systematic review of abreeant crypt foci and tumor data, ranked by potency. Nutr Cancer 43, 1-21, 2002.
25. Tatsuta M, Iishi H, Baba M, Yano H, Murata K, et al.: Suppression by apigenin of peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats. Clin Exp Metastasis 18, 657-662, 2001.
26. Roy HK, Karolski WJ, and Ratashak A: Distal bowel selectivity in the chemoprevention of experimental colon carcinogenesis by the non-steroidal anti-inflammatory drug nabumetone. Int J Cancer 92, 609-615, 2001.
27. Min mouse. Cancer Res 60, 5434-5440, 2000.
28. Shailubhai K, Yu HH, Karunanandaa K, Wang JY, Eber SL, et al.: R. Uroguanylin treatment suppresses polyp formation in the Apc(Min/+) mouse and induces apoptosis in human colon adenocarcinoma cells via cyclic GMP. Cancer Res 60, 5151-5157, 2000.