Site-specific mutagenesis of the histidine precursor of diphthamide in the human elongation factor-2 gene confers resistance to diphtheria toxin

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 609, Issue 1, 2006, Pages 34-42

  Ivankovic, Milena ^a   Rubelj, Ivica ^a   Matulic, Maja ^a   Reich, Edward ^b   Brdar, Branko ^a  

^a RUDER BO KOVI INSTITUTE   (Croatia)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Diphtheria toxin resistance; HeLa cells; Histidine precursor of diphthamide; Human elongation factor 2; Site specific mutagenesis

Indexed keywords

COMPLEMENTARY DNA; DIPHTHAMIDE HISTIDINE; DIPHTHERIA TOXIN; ELONGATION FACTOR 2; HISTIDINE; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CLONE; CELL CULTURE; CELL GROWTH; CELL ISOLATION; CELL KILLING; CELL PROTECTION; CELL STRAIN; CODON; CONTROLLED STUDY; DNA FINGERPRINTING; FEMALE; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INFECTION RESISTANCE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SITE DIRECTED MUTAGENESIS;

AMINO ACID SUBSTITUTION; CELL PROLIFERATION; DIPHTHERIA TOXIN; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, NEOPLASM; HELA CELLS; HISTIDINE; HUMANS; MUTAGENESIS, SITE-DIRECTED; PEPTIDE ELONGATION FACTOR 2; TRANSFECTION;

EUKARYOTA;

EID: 33748142394     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2006.06.027     Document Type: Article

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