Policy makers ignoring science and scientists ignoring policy: The medical ethical challenges of heroin treatment

Harm Reduction Journal

Volumn 3, Issue , 2006, Pages

  Small, Dan ^a,b   Drucker, Ernest ^c  

^a PHS Community Services Society   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIAMORPHINE; METHADONE; PENICILLIN G;

CANADA; CLINICAL PRACTICE; CLINICAL PROTOCOL; CLINICAL TRIAL; CRIMINAL BEHAVIOR; DOCTOR PATIENT RELATION; DRUG EFFICACY; DRUG SAFETY; EMPLOYMENT; EUROPE; FAMILY RELATION; GERMANY; HEALTH CARE POLICY; HEALTH STATUS; HEROIN DEPENDENCE; HUMAN; INTRAVENOUS DRUG ABUSE; MEDICAL ETHICS; NETHERLANDS; OPIATE ADDICTION; OUTCOMES RESEARCH; PATIENT COUNSELING; POLITICAL SYSTEM; PRESCRIPTION; PSYCHOTHERAPY; REVIEW; SOCIAL ASPECT; SPAIN; SWITZERLAND; WITHDRAWAL SYNDROME;

EID: 33748140703     PISSN: 14777517     EISSN: 14777517     Source Type: Journal    
DOI: 10.1186/1477-7517-3-16     Document Type: Review

References (52)

1. Jefferson T: Thomas Jefferson Monument. In Monument to Thomas Jefferson Washington, DC; Monument to Thomas Jefferson:1816.
2. Dolphin R: A Blistering Debate. Maclean's 1989:41.
3. Gossop M: Research Note-Prescribing Diamorphine for Medical Conditions: A Very British Practice. The Journal of Drug Issues 2004:441-450.
4. Metrebian N, Carnwath T, Stimson GV, Storz T: Survey of doctors prescribing diamorphine (heroin) to opiate-dependent drug users in the United Kingdom. Addiction 2002, 97:1155-1161.
5. Wall R, Rehm J, Fischer B, Brands B, Gliksman L, Stewart J, Medved W, Blake J: Social costs of untreated opioid dependence. Journal of Urban Health: Bulletin of the New York Academy of Science 2000, 77:688-722.
6. North America's first clinical trial of prescribed heroin begins toda [http://www.cihr-irsc.gc.ca/e/26516.html]
7. North America's First Heroin Prescription Program Introduced in Canada [http://www.worldpress.org/Americas/2054.cfm]
8. Bourdieu P: Language and Symbolic Power Cambridge, Massachussetts: Harvard University Press; 1995.
9. Fischer B, Rehm J, Brissette S, Brochu S, Bruneau J, El-Guebaly N, Noel L, Tyndall M, Wild C, Mun P, Baliunas D: Illicit Opioid Use in Canada: Comparing social, health, and drug use characteristics of untreated users in five cities (OPICAN study). Journal of Urban Health: Bulletin of the New York Academy of Medicine 2005, 82:250-266.
10. Tyndall MW, Kerr T, Zhang R, King E, Montaner JG, Wood E: Attendance, drug use patterns, and referrals made from North America's first supervised injection facility. Drug and Alcohol Dependence 2005 in press.
11. Blanken P, Henriks VM, Koeter MWJ, Ree JMv, Brink Wvd: Matching of treatment-resistant heroin-dependent patients to medical prescription of heroin or oral methadone treatment: results from two randomized controlled trials. Addiction 2005, 100:89-95.
12. Guttinger F, Gschwend P, Schulte B, Rehm J, Uchtenhagen A: Evaluating long-term effects of heroin-assisted treatment: the results of a 6-year follow-up. European Addiction Research 2003, 9:73-79.
13. Degenhardt L, Topp L: Crystal meth use among polydrug users in Syndney's dance party subculture: characteristics, use patterns and associated harms. International Journal of Drug Policy 2003, 14:17-24.
14. Fuente Ldl, Toro C, Soriano V, Brugal MT, Vallejo F, Barrio G, Jimenez V, Silva T: HTLV infection among young injection and non-injection heroir users in Spain: Prevalence and correlates. Journal of Clinical Virology 2006, 35:244-249.
15. Metrebian N, Shanahan W, Wells B, Stimson GV: Feasibility of prescribing injectable heroin and methadone to opiate-dependent drug users: associated health gains and harm reductions. The Medical Journal of Australia 1998, 168:596-600.
16. Haasen C, Prinzleve M, Zurhold H, Rehm J, Guttinger F, Fischer G, Jagsch R, Olsson B, Ekendahl M, Manning A, Cox G, Ryder N, Gerevich J, Bacskai E, Casas M, Matali J, Krausz M: Cocaine use in Europe: a multi-centre study. European Addiction Research 2004, 10:139-146.
17. Simson GV, Metrebian N: Prescribing heroin: what is the evidence? Joseph Rowntree Foundation 2003:1-60.
18. Uchenhagen A, A D-M, Steffen T, Gutzwiller F, Blattler R, Pfeifer S: Prescription of Narcotics for Heroin Addicts: Main Results of the Swiss National Cohort Study Zurich: Institute of Social and Preventative Medicine; University of Zurich; 1999.
19. Lewis D, Gear C, Loud ML, Langenick-Cartwright D, Eds: The Medical Prescription of Narcotics: Scientific Foundations and Practical Experiences. English edition. Toronto: Hogrefe and Huber; 1997.
20. Drucker E: Injectable heroin substitution treatment for opioid dependency. The Lancet 2001, 358:1385.
21. Drucker E, Vlahov D: Controlled clinical evaluation of diacetyl morphine for treatment of intractable opiate dependence. The Lancet 1999, 353:1543-1544.
22. W Vandenbrink VMH, Blanken P, Koeter MWJ, vanzweiten BJ, vanree JM: Medical prescription of heroin to treatment resistent resistant heroin addicts: two randomised controlled trials. British Medical Journal 2003, 327:1-6.
23. Krausz PDM: German model project of heroin-assisted treatment of opiate dependent patients-a multicentre, randomised, controlled treatment study. Hamburg, Germany: Centre for Interdisciplinary Addiction Research University of Hamburg; 2002.
24. The German project of heroin assisted treatment of opiate dependent patient [http://www.clinicaltrials.gov/ct/show/NCT00268814]
25. WHO WHO: Models of Medication Support for Opioid Addicts. Velen, Germany: World Health Organization Regional Office for Europe; 2002:1-71.
26. Germany: Heroin Pilot Project judged a Success [http://opiateaddictionrx.info/enews/Enewsmar06.htm#high02]
27. Germany's Heroin Trial: hold the applause.
28. Oviedo-Joekes E: Heroin treatment research. 2006.
29. Cordova J: Presentation of the Office of National Control Policy. Edited by: Small D. Washington, DC; 2005.
30. Bosch X: Spain authorizes clinical trial on heroin maintenance. The Lancet 2001, 357:1347.
31. Spain: Spain authorizes the use of heroin for clinical treatment [http://www.mapinc.org/drugnews/v01/n792/a02.html?131]
32. Fischer B: Heroin-assisted treatment as a response to the public health problem of opiate dependence. European Journal of Public Health 2002, 12:228-234.
33. March JC, Oviedo-Joekes E, Romero M, Gomez M, Rodriguez S, Leon MI, Rodriguez C: Captacion de participantes en el programa experimental de prescricion de estupefacientes en Andalucia. Gac Sanit 2004, 18:245-247.
34. March J, Oviedo-Joekes E, Perea-Milla E: Heroin-assisted treatment-an innovative element of the drug support system. 2006.
35. Brink Wvd, Hendriks VM, Blanken P, Huijsman IA, Ree JMv: Medical Co-Prescription of Heroin: Two Randomized Controlled Trials. Utrecht: Central Committee of the Treatment of Heroin Addicts 2002.
36. Blackmer J, Haddad H: The declaration of Helsinki: an update on paragraph 30. Canadian Medical Association Journal 2005, 173:1052-1053.
37. WMA WMA: World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. World Medical Association 2004.
38. WMA WMA: World Medical Association International Code of Medical Ethics. World Medical Association 1983.
39. Across the Generations: A History of Chinese in Canada [http://collections.ic.gc.ca/generations/index2.html]
40. The History of Leprosy in Canada: British Columbia: D'Arcy Island [http://www.leprosy.ca/site/c.anKKIPNrEqG/b.747889/k.A33E/ History_In_Canada.htm]
41. Dyck N: What is the Indian problem The Institute of Social Science and Economic Research; 1991.
42. The Tuskegee syphilis study: a hard lesson learned [http://www.cdc.gov/ nchstp/od/Tuskegee/time.htm]
43. Economist: Don't let it happen again. The Economist 1997, 343:27-28.
44. Shweder RA: The idea of moral progress. Philosophy of Education Yearbook 2003:29-56.
45. Lerner BH: Sins of omission-cancer research without informed consent. The New England Journal of Medicine 2004, 351:628-630.
46. Small D, Palepu A, Tyndall M: The establishment of North America's first state sanctioned supervision injection facility: A case study in culture change. The International Journal of Drug Policy 2006, 17:73-82.
47. INCB UNINCB: Report of the International Narcotics Control Board for 2003. Edited by: Board INC. United Nations; 2003.
48. Latour B: From the world of science to the world of research. Science 1998, 280:.
49. Miller CL, Schechter MT, Wood E, Spittal PM, Li K, Laliberte N, Montaner JS, Hogg RS: The potential health and economic impact of implementing a medical prescribed heroin program among Canadian injection drug users. International Journal of Drug Policy 2004, 15:259-263.
50. 2001 Report of the Auditor General of Canada: Chapter 11: Illicit Drugs: The Federal Government's Role [http://www.oag-bvg.gc.ca/domino/ reports.nsf/html/0111ce.html/$file/0111ce.pdf]
51. Fildes, Sir Luke: The Doctor [http://mchip00.nyu.edu/lit-med/lit-med-db/ webdocs/webart/fildes50-art-.html]
52. The Doctor [http://www.tate.org.uk/servlet/ ViewWork?cgroupid=999999961&workid=4277]