Decreased fidelity in replicating DNA methylation patterns in cancer cells leads to dense methylation of a CpG island

Current Topics in Microbiology and Immunology

Volumn 310, Issue , 2006, Pages 199-210

  Watanabe, N ^a   Okochi Takada, E ^a   Yagi, Y ^a   Furuta, J I ^a   Ushijima, T ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL ERROR; BREAST EPITHELIUM; CANCER CELL; CANCER CELL CULTURE; CELL CULTURE; CPG ISLAND; DNA METHYLATION; DNA REPLICATION; GENOME; HUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; REVIEW; STOMACH CANCER; BREAST; EPITHELIUM CELL; GENETICS; METABOLISM; NEOPLASM; STOMACH TUMOR;

BREAST; CPG ISLANDS; DNA METHYLATION; DNA REPLICATION; EPITHELIAL CELLS; HUMANS; NEOPLASMS; STOMACH NEOPLASMS;

EID: 33748106873     PISSN: 0070217X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/3-540-31181-5_10     Document Type: Review

References (25)

1. Abe M, Ohira M, Kaneda A, Yagi Y, Yamamoto S, Kitano Y, Takato T, Nakagawara A, Ushijima T (2005) CpG island methylator phenotype is a strong determinant of poor prognosis in neuroblastomas. Cancer Res 65:828-834
2. Bird A (2002) DNA methylation patterns and epigenetic memory. Genes Dev 16:6-21
3. Clark SJ, Harrison J, Paul CL, Frommer M (1994) High sensitivity mapping of methylated cytosines. Nucleic Acids Res 22:2990-2997
4. Costello JF, Fruhwald MC, Smiraglia DJ, Rush LJ, Robertson GP, Gao X, Wright FA, Feramisco JD, Peltomaki P, Lang JC, Schuller DE, Yu L, Bloomfield CD, Caligiuri MA, Yates A, Nishikawa R, Su Huang H, Petrelli NJ, Zhang X, O'Dorisio MS, Held WA, Cavenee WK, Plass C (2000) Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 24:132-138
5. De Smet C, Loriot A, Boon T (2004) Promoter-dependent mechanism leading to selective hypomethylation within the 5′ region of gene MAGE-A1 in tumor cells. Mol Cell Biol 24:4781-4790
6. Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB (1996) Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 93:9821-9826
7. Issa JP (2004) CpG island methylator phenotype in cancer. Nat Rev Cancer 4:988-993
8. Issa JP, Ottaviano YL, Celano P, Hamilton SR, Davidson NE, Baylin SB (1994) Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat Genet 7:536-540
9. Issa JP, Ahuja N, Toyota M, Bronner MP, Brentnall TA (2001) Accelerated age-related CpG island methylation in ulcerative colitis. Cancer Res 61:3573-3577
10. Jones PA, Baylin SB (2002) The fundamental role of epigenetic events in cancer. Nat Rev Genet 3:415-428
11. Kaneda A, Kaminishi M, Yanagihara K, Sugimura T, Ushijima T (2002) Identification of silencing of nine genes in human gastric cancers. Cancer Res 62:6645-6650
12. Laird CD, Pleasant ND, Clark AD, Sneeden JL, Hassan KM, Manley NC, Vary JC Jr, Morgan T, Hansen RS, Stoger R (2004) Hairpin-bisulfite PCR: assessing epigenetic methylation patterns on complementary strands of individual DNA molecules. Proc Natl Acad Sci USA 101:204-209
13. Pfeifer GP, Tanguay RL, Steigerwald SD, Riggs AD (1990a) In vivo footprint and methylation analysis by PCR-aided genomic sequencing: comparison of active and inactive X chromosomal DNA at the CpG island and promoter of human PGK-1. Genes Dev 4:1277-1287
14. Pfeifer GP, Steigerwald SD, Hansen RS, Gartler SM, Riggs AD (1990b) Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability. Proc Natl Acad Sci USA 87:8252-8256
15. Riggs AD, Xiong Z (2004) Methylation and epigenetic fidelity. Proc Natl Acad Sci USA 101:4-5
16. Sato N, Fukushima N, Maitra A, Matsubayashi H, Yeo CJ, Cameron JL, Hruban RH, Goggins M (2003) Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays. Cancer Res 63:3735-3742
17. Song JZ, Stirzaker C, Harrison J, Melki JR, Clark SJ (2002) Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells. Oncogene 21:1048-1061
18. Stirzaker C, Song JZ, Davidson B, Clark SJ (2004) Transcriptional gene silencing promotes DNA hypermethylation through a sequential change in chromatin modifications in cancer cells. Cancer Res 64:3871-3877
19. Toyota M, Ahuja N, Ohe-Toyota M, Herman JG, Baylin SB, Issa JP (1999) CpG island methylator phenotype in colorectal cancer. Proc Natl Acad Sci USA 96:8681-8686
20. Ushijima T (2005) Detection and interpretation of altered methylation in cancer cells. Nat Rev Cancer 5:223-231
21. Ushijima T, Okochi-Takada E (2005) Aberrant methylations in cancer cells: where do they come from? Cancer Sci 96:206-211
22. Ushijima T, Watanabe N, Okochi E, Kaneda A, Sugimura T, Miyamoto K (2003) Fidelity of the methylation pattern and its variation in the genome. Genome Res 13:868-874
23. Ushijima T, Watanabe N, Shimizu K, Miyamoto K, Sugimura T, Kaneda A (2005) Decreased fidelity in replicating CpG methylation patterns in cancer cells. Cancer Res 65:11-17
24. Wigler M, Levy D, Perucho M (1981) The somatic replication of DNA methylation. Cell 24:33-40
25. Yamashita K, Dai T, Dai Y, Yamamoto F, Perucho M (2003) Genetics supersedes epigenetics in colon cancer phenotype. Cancer Cell 4:121-131