Prognostic Value of KIT Exon 11 Deletions in GISTs

Gastroenterology

Volumn 131, Issue 3, 2006, Pages 976-977

  Emile, Jean François ^a   Tabone Eglinger, Séverine ^a   Théou Anton, Nathalie ^a   Lemoine, Antoinette ^a  

^a HÔPITAL AMBROISE PARÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COMPARATIVE STUDY; EXON; GASTROINTESTINAL STROMAL TUMOR; GENE DELETION; HUMAN; LETTER; MEDICAL TECHNOLOGY; MUTATION; PRIORITY JOURNAL; PROGNOSIS; SCIENCE; SIGNAL TRANSDUCTION;

EID: 33748104055     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2006.07.042     Document Type: Letter

References (4)

1. Andersson J., Bumming P., Meis-Kindblom J.M., Sihto H., Nupponen N., Joensuu H., Oden A., Gustavsson B., Kindblom L.G., and Nilsson B. Gastrointestinal stromal tumors with KIT exon 11 deletions are associated with poor prognosis. Gastroenterology 130 (2006) 1573-1581
2. Emile J.F., Theou N., Tabone S., Cortez A., Terrier P., Chaumette M.T., Julie C., Bertheau P., Lavergne-Slove A., Donadieu J., Barrier A., Le Cesne A., Debuire B., Lemoine A., and Groupe d'Etude des GIST. Clinicopathologic, phenotypic, and genotypic characteristics of gastrointestinal mesenchymal tumors. Clin Gastroenterol Hepatol 2 (2004) 597-605
3. Martin J., Poveda A., Llombart-Bosch A., Ramos R., Lopez-Guerrero J.A., Garcia del Muro J., Maurel J., Calabuig S., Gutierrez A., Gonzalez de Sande J.L., Martinez J., De Juan A., Lainez N., Losa F., Alija V., Escudero P., Casado A., Garcia P., Blanco R., Buesa J.M., and Spanish Group for Sarcoma Research. Deletions affecting codons 557-558 of the c-KIT gene indicate a poor prognosis in patients with completely resected gastrointestinal stromal tumors: a study by the Spanish Group for Sarcoma Research (GEIS). J Clin Oncol 23 (2005) 6190-6191
4. Wardelmann E., Losen I., Hans V., Neidt I., Speidel N., Bierhoff E., Heinicke T., Pietsch T., Buttner R., and Merkelbach-Bruse S. Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors. Int J Cancer 106 (2003) 887-895