Outcomes of cardiac surgery in the elderly

Expert Review of Cardiovascular Therapy

Volumn 4, Issue 4, 2006, Pages 535-542

  Drury, Nigel E ^a   Nashef, Samer A M ^a  

^a PAPWORTH HOSPITAL   (United Kingdom)

Author keywords

Aortic valve disease; Cardiac surgery; Elderly; Outcome; Revascularization; Risk factors

Indexed keywords

CARDIOVASCULAR AGENT;

AGED; AGING; AORTA STENOSIS; AORTA SURGERY; AORTA VALVE REPLACEMENT; CARDIOPULMONARY BYPASS; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; COMORBIDITY; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY DISEASE; DRUG ELUTING STENT; ELDERLY CARE; ELECTIVE SURGERY; FALLOT TETRALOGY; GRAFT SURVIVAL; HEART ATRIUM FIBRILLATION; HEART FAILURE; HEART MUSCLE REVASCULARIZATION; HEART SURGERY; HEART VALVE PROSTHESIS; HIGH RISK PATIENT; HUMAN; INTERMETHOD COMPARISON; META ANALYSIS; MITRAL VALVE DISEASE; OFF PUMP CORONARY SURGERY; PERCUTANEOUS CORONARY INTERVENTION; PERIOPERATIVE PERIOD; POSTOPERATIVE COMPLICATION; PREDICTION; PREOPERATIVE CARE; QUALITY OF LIFE; REOPERATION; REVIEW; RISK ASSESSMENT; RISK BENEFIT ANALYSIS; RISK REDUCTION; SURGICAL MORTALITY; SURGICAL RISK; SURVIVAL RATE; SURVIVAL TIME; SYSTEMATIC REVIEW; TREATMENT INDICATION; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; AORTIC VALVE STENOSIS; CARDIAC SURGICAL PROCEDURES; COMORBIDITY; CORONARY ARTERY BYPASS; CORONARY ARTERY BYPASS, OFF-PUMP; HEART DISEASES; HEART VALVE DISEASES; HEART VALVE PROSTHESIS IMPLANTATION; HUMANS; MITRAL VALVE; MYOCARDIAL REVASCULARIZATION; OUTCOME ASSESSMENT (HEALTH CARE); PATIENT SELECTION; QUALITY OF LIFE; RISK ASSESSMENT; RISK FACTORS; STENTS;

EID: 33748102044     PISSN: 14779072     EISSN: 17448344     Source Type: Journal    
DOI: 10.1586/14779072.4.4.535     Document Type: Review

References (67)

1. American Heart Association. Heart disease and stroke statistics - 2005 update. American Heart Association, TX, USA (2005).
2. Anderson RN, Smith BL. Deaths: leading causes for 2002. National vital statistics reports; vol 53 no 17. National Center for Health Statistics, MA, USA (2005).
3. Klein LW, Block P, Brindis RG et al; ACC-NCDR registry. Percutaneous coronary interventions in octogenarians in the American College of Cardiology-National Cardiovascular Data Registry. Development of a nomogram predictive of in-hospital mortality. J. Am. Coll. Cardiol. 40, 394-402 (2002).
4. Bond M, Bowling A, McKee D et al. Does ageism affect the management of ischaemic heart disease? J. Health Serv. Res. Policy 8, 40-47 (2003).
5. Stone PH, Thompson B, Anderson HV et al. Influence of race, sex and age on management of unstable angina and non-Q wave myocardial infarction. The TIMI III registry. JAMA 275, 1104-1112 (1996).
6. Alexander KP, Anstrom KJ, Muhlbaier LH et al. Outcomes of cardiac surgery in patients age ≥80 years: results from the National Cardiovascular Network. J. Am. Coll. Cardiol. 35, 731-738 (2000).
7. Bridges CR, Edwards FH, Peterson ED, Coombs LP, Ferguson TB. Cardiac surgery in nonagenarians and centenarians. J. Am. Coll. Surg. 197, 347-357 (2003).
8. Keogh B, Kinsman R. National adult cardiac surgical database report 2000-2001. Society of Cardiothoracic Surgeons of Great Britain and Ireland, London, UK (2002).
9. Peterson ED, Alexander KP, Malenka DJ et al; American Heart Association Chronic CAD working group. Multicenter experience in revascularization of very elderly patients. Am. Heart J. 148, 486-492 (2004).
10. Lee P, Alexander K, Hammill B, Pasquali S, Peterson E. Representation of elderly persons and women in published randomized trials of acute coronary syndromes. JAMA 286, 708-713 (2001).
11. Bowling A. Ageism in cardiology. Br. Med. J. 319, 1353-1355 (1999).
12. Parsonnet V, Dean D, Bernstein AD. A method of uniform stratification of risk for evaluating the results of surgery in acquired adult heart disease. Circulation 79, 13-112 (1989).
13. Michel P, Roques F, Nashef SAM, the EuroSCORE Project Group. Logistic or additive EuroSCORE for high-risk patients? Eur. J. Cardiothorac. Surg. 23, 684-687 (2003).
14. Jones RH, Hannan EL, Hammermeister KE et al. Identification of preoperative variables needed for risk adjustment of short-term mortality after coronary artery bypass graft surgery. The Working Group Panel on the Cooperative CABG Database Project. J. Am. Coll. Cardiol. 28, 1478-1487 (1996).
15. TIME investigators. Trial of invasive versus medical therapy in elderly patients with chronic symptomatic coronary-artery disease (TIME): a randomised trial. Lancet 358, 951-957 (2001).
16. Graham MM, Ghali WA, Faris PD, Galbraith PD, Norris CM, Knudtson ML. Survival after coronary revascularization in the elderly. Circulation 105, 2378-2384 (2002).
17. Batchelor WB, Anstrom KJ, Muhlbaier LH et al. Contemporary outcome trends in the elderly undergoing percutaneous coronary interventions: results in 7,472 octogenarians. National Cardiovascular Network Collaboration. J. Am. Coll. Cardiol. 36, 723-730 (2000).
18. De Gregorio J, Kobayashi Y, Albiero R et al. Coronary artery stenting in the elderly: short-term outcome and long-term angiographic and clinical follow-up. J. Am. Coll. Cardiol. 32, 577-583 (1998).
19. Kowalchuk CJ, Sin SC, Lewis SM. Coronary artery disease in the octogenarian: angiographic spectrum and suitability for revascularization. Am. J. Cardiol. 66, 1319-1323 (1990).
20. Peterson ED, Cowper PA, Jollis JG et al. Outcomes of coronary artery bypass graft surgery in 24 461 patients aged 80 years or older. Circulation 92, II85-II91 (1995).
21. Enorgen M, Arslanian-Enorgen C, Steckel D, Neihardt J, Fenn-Buderer N. Cost, outcome and functional status in octogenarians and septuagenarians after cardiac surgery. Chest 122, 1309-1315 (2002).
22. Avery GJ II, Ley SJ, Hill JD, Hershon JJ, Dick SE. Cardiac surgery in the octogenarian: evaluation of risk, cost and outcome. Ann. Thorac. Surg. 71, 591-596 (2001).
23. Conaway DG, House J, Bandt K, Hayden L, Borkon AM, Spertus JA. The elderly: health status benefits and recovery of function one year after coronary artery bypass surgery. J. Am. Coll. Cardiol. 42, 1421-1426 (2003).
24. Collins SM, Bronson B, Svenmarker S, Kling PA, Åberg T. Medium-term survival and quality of life of Swedish octogenarians after open-heart surgery. Eur. J. Cardiothorac. Surg. 22, 794-801 (2002).
25. Fruitman DS, MacDougall CE, Ross DB. Cardiac surgery in octogenarians: can elderly patients benefit? Quality of life after cardiac surgery. Ann. Thorac. Surg. 68, 2129-2135 (1999).
26. Sjögren J, Thulin LI. Quality of life in the very elderly after cardiac surgery: a comparison of SF-36 between long-term survivors and an age-matched population. Gerontology 50, 407-410 (2004).
27. Kolh P, Kerzmann A, Lahaye L, Gerard P, Limer R. Cardiac surgery in octogenarians. Peri-operative outcome and long-term results. Eur. Heart J. 22, 1235-1243 (2001).
28. Mittermair RP, Müller LC. Quality of life after cardiac surgery in the elderly. J. Cardiovasc. Surg. (Torino) 43, 43-47 (2002).
29. Edwards FH, Clark RE, Schwartz M. Impact of internal mammary artery conduits on operative mortality in coronary revascularization. Ann. Thorac. Surg. 57, 27-32 (1994).
30. Stoica SC, Cafferty F, Kitcat J et al. Octogenarians undergoing cardiac surgery outlive their peers: a case for early referral. Heart 92, 503-506 (2006).
31. Athanasiou T, Al-Ruzzeh S, Kumar P et al. Off-pump myocardial revascularization is associated with less incidence of stroke in elderly patients. Ann. Thorac. Surg. 77, 745-753 (2004).
32. Demaria RG, Carrier M, Fortier S et al. Reduced mortality and strokes with off-pump coronary artery bypass grafting surgery in octogenarians. Circulation 106, I5-I10 (2002).
33. Murphy GJ, Bryan AJ, Angelini GD. Hybrid coronary revascularization in the era of drug-eluting stents. Ann. Thorac. Surg. 78, 1861-1867 (2004).
34. Stewart BF, Siscovick D, Lind BK et al. Clinical factors associated with calcific aortic valve disease. J. Am. Coll. Cardiol. 29, 630-634 (1997).
35. Lindroos M, Kupari M, Heikkila J, Tilvis R. Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample. J. Am. Coll. Cardiol. 21, 1220-1225 (1993).
36. Bonow RO, Carabello B, de Leon AC Jr et al. Guidelines for the management of patients with valvular heart disease: executive summary. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Valvular Heart Disease). Circulation 98, 1949-1984 (1998).
37. Bramstedt KA. Aortic valve replacement in the elderly: frequently indicated yet frequently denied. Gerontology 49, 46-49 (2003).
38. Bouma BJ, van den Brink RBA, van der Meulen JHP et al. To operate or not on elderly patients with aortic stenosis: the decision and its consequences. Heart 82, 143-148 (1999).
39. Iung B, Cachier A, Baron G et al. Decision-making in elderly patients with severe aortic stenosis: why are so many denied surgery? Eur. Heart J. 26, 2714-2720 (2005).
40. O'Keefe JH Jr, Vlietstra RE, Bailey KR, Holmes DR Jr. Natural history of candidates for balloon aortic valvuloplasty. Mayo Clin. Proc. 62, 986-991 (1987).
41. Otto CM, Mickel MC, Kennedy JW et al. Three-year outcome after balloon aortic valvuloplasty. Insights into prognosis of valvular aortic stenosis. Circulation 89, 642-650 (1994).
42. Nowicki ER, Birkmeyer NJ, Weintraub RW et al. Multivariable prediction of in-hospital mortality associated with aortic and mitral valve surgery in Northern New England. Ann. Thorac. Surg. 77, 1966-1977 (2004).
43. Chiappini B, Camurri N, Loforte A, Di Marco L, Di Bartolomeo R, Marinelli G. Outcome after aortic valve replacement in octogenarians. Ann. Thorac. Surg. 78, 85-89 (2004).
44. Elayda MA, Hall RJ, Reul RM et al. Aortic valve replacement in patients 80 years and older. Operative risks and long-term results. Circulation 88, 1111-1116 (1993).
45. Dalrymple-Hay MJR, Alzetani A, Aboel-Nazar S, Haw M, Livesey S, Monro J. Cardiac surgery in the elderly. Eur. J. Cardiothorac. Surg. 15, 61-66 (1999).
46. Akins CW, Daggett WM, Vlahakes GJ et al. Cardiac operations in patients 80 years old and older. Ann. Thorac. Surg. 64, 606-615 (1997).
47. Sundt TM, Bailey MS, Moon MR et al. Quality of life after aortic valve replacement at the age of >80 years. Circulation 102, III70-III74 (2000).
48. Gehlot A, Mullany CJ, Ilstrup D et al. Aortic valve replacement in patients aged eighty years and older: early and long-term results. J. Thorac. Cardiovasc. Surg. 111, 1026-1036 (1996).
49. Florath I, Albert A, Rosendahl U, Alexander T, Ennker IC, Ennker J. Mid term outcome and quality of life after aortic valve replacement in elderly people: mechanical versus stentless biological valves. Heart 91, 1023-1029 (2005).
50. Ennker J, Rosendahl U, Ennker IC, Bauer S, Florath I. Risk in elderly patients after stentless versus stented aortic valve surgery. Asian Cardiovasc. Thorac. Ann. 11, 37-41 (2003).
51. Medalion B, Lytle BW, McCarthy PM et al. Aortic valve replacement for octogenarians: are small valves bad? Ann. Thorac. Surg. 66, 699-706 (1998).
52. Mehra RH, Eagle KA, Coombs LP et al. Influence of age on outcomes in patients undergoing mitral valve replacement. Ann. Thorac. Surg. 74, 1459-1467 (2002).
53. Nagendran J, Norris C, Maitland A, Koshall A, Ross DB. Is mitral valve surgery safe in octogenarians? Eur. J. Cardiothorac. Surg. 28, 83-87 (2005).
54. Smith WT IV, Ferguson TB, Ryan T, Landolfo CK; Peterson ED. Should coronary artery bypass graft surgery patients with mild or moderate aortic stenosis undergo concomitant aortic valve replacement? J. Am. Coll. Cardiol. 44, 1241-1247 (2004).
55. Gillinov AM, Garcia MJ. When is concomitant aortic valve replacement indicated in patients with mild to moderate stenosis undergoing coronary revascularization? Curr. Cardiol. Rep. 7, 101-104 (2005).
56. Santini F, Montalbano G, Messina A et al. Survival and quality of life after repair of acute type A aortic dissection in patients aged 75 years and older justify intervention. Eur. J. Cardiothorac. Surg. 29, 386-391 (2006).
57. Ishida Y, Kawasuji M, Sakakibara N et al. A case report of total repair in a 71-year-old patient with tetralogy of Fallot. Kyobu Geka 54, 225-227 (2001).
58. Menkis AH. Management of the ascending aorta in routine cardiac surgery. Semin. Cardiothorac. Vasc. Anesth. 8, 19-24 (2004).
59. Byrne JG, Leacche M, Unic D et al. Staged initial percutaneous coronary intervention followed by valve surgery ('hybrid approach) for patients with complex coronary and valve disease. J. Am. Coll. Cardiol. 45, 14-48 (2005).
60. Feinberg WM, Blackshear JL, Laupacis A, Kronmal R, Hart RG. Prevalence, age distribution and gender of patients with atrial fibrillation. Analysis and implications. Arch. Intern. Med. 155, 469-473 (1995).
61. Braunwald E. Shattuck lecture - cardiovascular medicine at the turn of the millennium: triumphs, concerns and opportunities. N. Engl. J. Med. 337, 1360-1369 (1997).
62. Prasad SM, Maniar HS, Camillo CJ et al. The Cox maze III procedure for atrial fibrillation: long-term efficacy in patients undergoing lone versus concomitant procedures. J. Thorac. Cardiovasc. Surg. 126, 1822-1828 (2003).
63. Ninet J, Roques X, Seitelberger R et al. Surgical ablation of atrial fibrillation with off-pump, epicardial, high-intensity focused ultrasound: results of a multicenter trial. J. Thorac. Cardiovasc. Surg. 130, 803-809 (2005).
64. Stewart S. MacIntyre K, Capewell S, McMurray JJV. Heart failure and the aging population: an increasing burden in the 21st century? Heart 89, 49-53 (2003).
65. DeBakey ME, Teitel ER. Use of the MicrMed DeBakey VAD for the treatment of end-stage heart failure. Expert Rev. Med. Devices 2(2), 137-140 (2005).
66. Maurer MS. Age: a non-modifiable risk factor? J. Am. Coll. Cardiol. 42, 1427-1428 (2003).
67. Alvarez JMP. Cardiac surgery in octogenarians and beyond. Should we do it, is it worthwhile and who should decide? Med. J. Aust. 181, 181-182 (2004).