Allergic tears promote upregulation of eosinophil adhesion to conjunctival epithelial cells in an ex vivo model: Inhibition with olopatadine treatment

Investigative Ophthalmology and Visual Science

Volumn 47, Issue 8, 2006, Pages 3423-3429

  Cook, Ellen B ^a   Stahl, James L ^a   Brooks, Anne M ^a   Graziano, Frank M ^a   Barney, Neal P ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA2 INTEGRIN; CD18 ANTIGEN; EOSINOPHIL PEROXIDASE; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; OLOPATADINE; RANTES; ANTIALLERGIC AGENT; BLOCKING ANTIBODY; DIBENZOXEPIN DERIVATIVE;

ADULT; ALLERGY; ARTICLE; CADAVER; CELL ADHESION; CLINICAL ARTICLE; CONJUNCTIVA EPITHELIUM; CONTROLLED STUDY; EOSINOPHILIA; EX VIVO STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; INCUBATION TIME; LACRIMAL FLUID; MALE; MICROCIRCULATION; PRIORITY JOURNAL; ALLERGIC CONJUNCTIVITIS; BIOLOGICAL MODEL; CELL CULTURE; CELL SEPARATION; CONJUNCTIVA; CYTOLOGY; DRUG EFFECT; EOSINOPHIL; EPITHELIUM CELL; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PHYSIOLOGY; SKIN TEST; UPREGULATION;

ADULT; ANTI-ALLERGIC AGENTS; ANTIBODIES, BLOCKING; ANTIGENS, CD18; CELL ADHESION; CELL SEPARATION; CELLS, CULTURED; CONJUNCTIVA; CONJUNCTIVITIS, ALLERGIC; DIBENZOXEPINS; EOSINOPHILS; EPITHELIAL CELLS; FEMALE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; SKIN TESTS; TEARS; UP-REGULATION;

EID: 33748094133     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.06-0088     Document Type: Article

References (31)

1. Miyoshi T, Fukagawa K, Shimmura S, et al. Interleukin-8 concentrations in conjunctival epithelium brush cytology samples correlate with neutrophil, eosinophil infiltration, and corneal damage. Cornea. 2001;20:743-747.
2. Bonini S, Bonini S, Lambiase A, et al. Vernal keratoconjunctivitis: a model of 5q cytokine gene cluster disease. Int Arch Allergy Immunol. 1995;107:95-98.
3. Leonardi A, Borghesan F, Faggian D, Secchi A, Plebani M. Eosinophil cationic protein in tears of normal subjects and patients affected by vernal keratoconjunctivitis. Allergy. 1995;50:610-613.
4. Montan PG, van Hage-Hamsten M. Eosinophil cationic protein in tears in allergic conjunctivitis. Br J Ophthalmol. 1996;80:556-560.
5. Oh JW, Shin JC, Jang SJ, Lee HB. Expression of ICAM-1 on conjunctival epithelium and ECP in tears and serum from children with allergic conjunctivitis. Ann Allergy Asthma Immunol. 1999;82:579-585.
6. Baudouin C, Haouat N, Brignole F, et al. Immunopathological findings in conjunctival cells using immunofluorescence staining of impression cytology specimens. Br J Ophthalmol. 1992;76:545-549.
7. Baudouin C, Brignole F, Becquet F, et al. Flow cytometry in impression cytology specimens: a new method for evaluation of conjunctival inflammation. Invest Ophthalmol Vis Sci. 1997;38:1458-1464.
8. Cook EB, Stahl JL, Sedgwick JB, Barney NP, Graziano FM. The promotion of eosinophil degranulation and adhesion to conjunctival epithelial cells by IgE-activated conjunctival mast cells. Ann Allergy Asthma Immunol. 2004;92:65-72.
9. Cook EB, Stahl JL, Barney NP, Graziano FM. Olopatadine inhibits anti-IgE stimulated conjunctival mast cell upregulation of ICAM-1 expression on conjunctival epithelial cells. Ann Allergy Asthma Immunol. 2001;87:424-429.
10. Xia Y, Borland G, Huang J, et al. Function of the lectin domain of Mac-1/complement receptor type 3 (CD11b/CD18) in regulating neutrophil adhesion. J Immunol. 2002;169:6417-6426.
11. Sanmugalingham D, De Vries E, Gauntlett R, Symon FA, Bradding P, Wardlaw AJ. Interleukin-5 enhances eosinophil adhesion to bronchial epithelial cells. Clin Exp Allergy. 2000;30:255-263.
12. Olszewska-Pazdrak B, Pazdrak K, Ogra PL Garofalo RP. Respiratory syncytial virus-infected pulmonary epithelial cells induce eosinophil degranulation by a CD18-mediated mechanism. J Immunol. 1998;160:4889-4995.
13. Sato M, Takizawa H, Kohyama T, et al. Eosinophil adhesion to human bronchial epithelial cells: regulation by cytokines. Int Arch Allergy Immunol. 1997;113:203-205.
14. Carreno MP, Chomont N, Kazatchkine MD, et al. Binding of LFA-1 (CD11a) to intercellular adhesion molecule 3 (ICAM-3; CD50) and ICAM-2 (CD102) triggers transmigration of human immunodeficiency virus type 1-infected monocytes through mucosal epithelial cells. J Virol. 2002;75:32-40.
15. Wong CK, Wang CB, Ip WK, Tian YP, Lam CW. Role of p38 MAPK and NF-κB for chemokine release in coculture of human eosinophils and bronchial epithelial cells. Clin Exp Immunol. 2005;139:90-100.
16. Leonardi A, Brun P, Sartori MT, et al. Urokinase plasminogen activator, uPA receptor, and its inhibitor in vernal keratoconjunctivitis. Invest Ophthalmol Vis Sci. 2005;46:1364-1370.
17. Gipson IK. Distribution of mucins at the ocular surface. Exp Eye Res. 2004;78:379-388.
18. Leonardi A, Abelson MB. Double-masked, randomized, placebo-controlled clinical study of the mast cell-stabilizing effects of treatment with olopatadine in the conjunctival allergen challenge model in humans. Clin Ther. 2003;25:2539-2552.
19. Miller S, Cook E, Graziano FM, Spellman J, Yanni J. Human conjunctival mast cell responses in vitro to various secretagogues. Ocul Immunol Inflamm. 1996;4:39-49.
20. Cook EB, Stahl JL, Miller S, et al. Isolation of human conjunctival mast cells and epithelial cells: tumor necrosis factor-alpha from mast cells affects intercellular adhesion molecule-1 expression on epithelial cells. Invest Ophthalmol Vis Sci. 1998;39:336-343.
21. Yamamoto H, Sedgwick JB, Busse WW. Differential regulation of eosinophil adhesion and transmigration by pulmonary microvascular endothelial cells. J Immunol. 1998;161:971-977.
22. Diamond MS, Staunton DE, de Fougerolles AR, et al. ICAM-1 (CD54): a counter-receptor for Mac-1 (CD11b/CD18). J Cell Biol. 1990;111:3129-3139.
23. Cook EB, Stahl JL, Lowe L, et al. Simultaneous measurement of multiple cytokines in a single sample of human tears using microparticle-based flow cytometry. J Immunol Methods. 2001;254:109-118.
24. Sharif NA, Xu SX, Miller ST, Gamache DA, Yanni JM. Characterization of the ocular antiallergic and antihistaminic effects of olopatadine (AL-4943A), a novel drug for treating ocular allergic diseases. J Pharmacol Exp Ther. 1996;278:1252-1261.
25. Cook EB, Stahl JL, Barney NP, Graziano FM. Olopatadine inhibits TNFα release from human conjunctival mast cells. Ann Allergy Asthma Immunol. 2000;84:504-508.
26. Kalesnikoff J, Lam V, Krystal G. SHIP represses mast cell activation and reveals that IgE alone triggers signaling pathways which enhance normal mast cell survival. Mol Immunol. 2001;38:1201-1206.
27. Sada K, Miah SM, Maeno K, Kyo S, Qu X, Yamamura H. Regulation of FceRI-mediated degranulation by an adaptor protein 3BP2 in rat basophilic leukemia RBL-2H3 cells. Blood. 2002;100:2138-2144.
28. Stahl JL, Cook EB, Graziano FM, Barney NP. Differential and cooperative effects of TNF alpha, IL-1 beta, and IFN gamma on human cell conjunctival epithelial cell receptor expression and chemokine release. Invest Ophthalmol Visual Sci. 2003;44:2010-2015.
29. Leonardi A, Brun P, Tavolato M, Abatangelo G, Plebani M, Secchi AG. Growth factors and collagen distribution in vernal keratoconjunctivitis. Invest Ophthalmol Vis Sci. 2000;41:4175-4181.
30. Abu El-Asrar AM, Van Aelst I, Al-Mansouri S, Missotten L, Opdenakker G, Geboes K. Gelatinase B in vernal keratoconjunctivitis. Arch Ophthalmol. 2001;119:1505-1511.
31. Abelson MB. A review of olopatadine for the treatment of ocular allergy. Expert Opin Pharmacother. 2004;1979-1994.