The contribution of PspC to pneumococcal virulence varies between strains and is accomplished by both complement evasion and complement-independent mechanisms

Infection and Immunity

Volumn 74, Issue 9, 2006, Pages 5319-5324

  Kerr, Alison R ^a   Paterson, Gavin K ^a,c   McCluskey, Jackie ^a   Iannelli, Francesco ^b   Oggioni, Marco R ^b   Pozzi, Gianni ^b   Mitchell, Tim J ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF SIENA   (Italy)

^c DEFENCE SCIENCE AND TECHNOLOGY LABORATORY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT; COMPLEMENT COMPONENT C3; PNEUMOCOCCAL SURFACE PROTEIN C; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTEREMIA; BACTERIAL GENE; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; CELL INVASION; COMPLEMENT ACTIVATION; COMPLEMENT DEFICIENCY; CONTROLLED STUDY; FEMALE; GENE DELETION; LOBAR PNEUMONIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PSPC GENE; SEROTYPE; STATISTICAL ANALYSIS; STREPTOCOCCUS PNEUMONIAE; SURVIVAL TIME; WILD TYPE;

ANIMALS; BACTEREMIA; BACTERIAL PROTEINS; COMPLEMENT SYSTEM PROTEINS; DISEASE MODELS, ANIMAL; FEMALE; GENE DELETION; MEMBRANE PROTEINS; MICE; MICE, MUTANT STRAINS; PNEUMONIA, PNEUMOCOCCAL; STREPTOCOCCUS PNEUMONIAE;

EID: 33748051087     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.00543-06     Document Type: Article

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