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Effect of repeated infliximab therapy on serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in patients with rheumatoid arthritis
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Baseline factors that influence ASAS 20 response in patients with ankylosing spondylitis treated with etanercept
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Davis JC Jr, Van der Heijde DM, Dougados M, et al. Baseline factors that influence ASAS 20 response in patients with ankylosing spondylitis treated with etanercept. J Rheumatol 2005; 32:1751-1754.
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Serum levels of matrix metalloproteinase 3 and macrophage colony-stimulating factor 1 correlate with disease activity in ankylosing spondylitis
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Lack of association of matrix metalloproteinase 3 (MMP3) genotypes with ankylosing spondylitis susceptibility and severity
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Serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in ankylosing spondylitis: MMP-3 is a reproducibly sensitive and specific biomarker of disease activity
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Oxford November 15 [Epub ahead of print]
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Chen CH, Lin KC, Yu DT, et al. Serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in ankylosing spondylitis: MMP-3 is a reproducibly sensitive and specific biomarker of disease activity. Rheumatology (Oxford) 2005; November 15 [Epub ahead of print]. This was the only study to calculate the sensitivity and specficity of serum MMP-3 levels in assessing disease activity in ankylosing spondylitis. It also compared results of two different cohorts.
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Rheumatology
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Chen, C.H.1
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Infliximab in ankylosing spondylitis: A prospective observational inception cohort analysis of efficacy and safety
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Etanercept exerts beneficial effects on articular cartilage biomarkers of degradation and turnover in patients with ankylosing spondylitis
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Maksymowych WP, Poole AR, Hiebert L, et al. Etanercept exerts beneficial effects on articular cartilage biomarkers of degradation and turnover in patients with ankylosing spondylitis. J Rheumatol 2005; 32:1911-1917. This was the only study on the effect of etanercept on serum MMP levels.
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Maksymowych, W.P.1
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