Changes in cerebral membrane lipid composition and fluidity during thioacetamide-induced hepatic encephalopathy

Journal of Neurochemistry

Volumn 98, Issue 6, 2006, Pages 1899-1907

  Swapna, I ^a   SathyaSaiKumar, K V ^a   Murthy, Ch R K ^a   Dutta Gupta, A ^a   Senthilkumaran, B ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

Fatty acids; Fluidity; Hepatic encephalopathy; Phospholipids; Thioacetamide

Indexed keywords

1,6 DIPHENYL 1,3,5 HEXATRIENE; ARACHIDONIC ACID; CHOLESTEROL; FATTY ACID; HEXANOIC ACID; LINOLEIC ACID; MEMBRANE LIPID; MEMBRANE PHOSPHOLIPID; OLEIC ACID; POLYUNSATURATED FATTY ACID; PYRENE; SPHINGOMYELIN; THIOACETAMIDE; UNSATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL MEMBRANE FLUIDITY; CONTROLLED STUDY; HEPATIC ENCEPHALOPATHY; LIPID COMPOSITION; LIPID PEROXIDATION; LIVER FAILURE; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PREVALENCE; PRIORITY JOURNAL; PSYCHIATRY; RAT;

ANIMALS; BRAIN; CHOLESTEROL; FATTY ACIDS; HEPATIC ENCEPHALOPATHY; LIPID METABOLISM; LIPID PEROXIDATION; MALE; MEMBRANE FLUIDITY; MEMBRANES; PHOSPHOLIPIDS; PLASMALOGENS; RATS; RATS, WISTAR; SULFHYDRYL COMPOUNDS; THIOACETAMIDE;

EID: 33748036414     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04028.x     Document Type: Article

References (58)

1. An X., Guo X., Sum H., Morrow J., Gratzer W. and Mohandas N. (2004) Phosphatidylserine binding sites in erythroid spectrin: location and implications for membrane stability. Biochemistry 43, 310-315.
2. Avdulov N. A., Chochina S. V., Igbavboa U., O'are E. O., Schroeder F., Cleary J. P. and Wood W. G. (1997) Amyloid betapeptides increase annular and bulk fluidity and induce lipid peroxidation in brain synaptic plasma membranes. J. Neurochem. 68, 2086-2091.
3. Barlett G. R. (1959) Phosphorus assay in column chromatography. J. Biol. Chem. 234, 466-468.
4. Björkhem I. and Meaney S. (2004) Brain cholesterol: Long secret life behind a barrier. Arterioscler. Thromb. Vasc. Biol. 24, 806-815.
5. Bollinger C. R., Teichgraber V. and Gulbins E. (2005) Ceramide enriched membrane domains. Biochim. Biophys. Acta 1746, 284-294.
6. 2+/phosphatidylserine binding region of the C2 domain in the transloacation of protein kinase C alpha to the plasma membrane. J. Biol. Chem. 278, 10 282-10 290.
7. Butterworth R. F., Giguere J. F., Michaud J., Lavoie J. and Layragues G. P. (1987) Ammonia: Key factor in the pathogenesis of hepatic encephalopathy. Neurochem. Pathol. 6, 1-12.
8. Caballero M. E., Berlanga J., Ramirez D., Lopez-Saura P., Gozalez R., Floyd D. N., Marchbank T. and Playford R. J. (2001) Epidermal growth factor reduces multiorgan failure induced by thioacetamide. Gut 48, 34-40.
9. Choi J. H. and Yu B. P. (1990) Unsuitability of TBA test as a lipid peroxidation marker due to prostaglandin synthesis in the ageing kidney. Age 13, 61-64.
10. Chou Y. C., Lin S. B., Tsai L. S., Tsai H. I. and Lin C. M. (2003) Cholesterol deficiency increases the vulnerability of hippocampal glia in primary culture to glutamate-induced excitotoxicity. Neurochem. Int. 43, 197-209.
11. Comporti M. (1985) Lipid peroxidation and cellular damage in toxic liver injury. Laboratory Invest. 53, 599-623.
12. Denisova N. A., Cantuti-castelvetri I., Hassan W. N., Paulson K. E. and Joseph J. A. (2001) Role of membrane lipids in regulation of vulnerability to oxidative stress in PC12 cells: implication for ageing. Free Radic. Biol. Med. 30, 671-678.
13. Faa G., Ambu R., Congiu T., Costa V., Ledda Columbano G. M., Coni P., Curto M., Giacomini L. and Columbano A. (1992) Early ultrastructural changes during thioacetamide-induced apoptosis in rat liver. J. Submicrosc. Cytol. Pathol. 24, 417-424.
14. Farooqui A. A. and Horrocks L. A. (1985) Metabolic and functional aspects of neural membrane phospholipids, in Phopholipids in Nervous System: Physiological Role (Horrocks L. A., Kanfer J. N. and Porcellati G., eds), Vol. 2, pp. 341-348. Raven Press, New York.
15. Felipo V. and Butterworth R. (2002) Neurobiology of ammonia. Prog. Neurobiol. 67, 259-279.
16. Felipo V., Grau E., Minana M. D. and Grisolia S. (1993) Hyperammonemia decreases protein kinase- C dependent phosphorylation of microtubule- associated protein 2 and increases its binding to tubulin. Eur. J. Biochem. 214, 243-249.
17. Folch J., Ascoli I., Lees M., Meath J. A. and Le Baron F. N. (1951) Preparation of lipid extracts from brain tissue. J. Biol. Chem. 191, 833-841.
18. Gagne J., Giguere C., Tocco G., Ohayon M., Thompson R. F., Baudry M. and Massicotte G. (1996) Effect of phosphatidylserine on the binding properties of glutamate receptors in brain sections from adult and neonatal rats. Brain Res. 740, 337-345.
19. Ghosh C., Dick R. M. and Ali S. F. (1993) Iron/ascorbate-induced lipid peroxidation changes membrane fluidity and muscarinic cholinergic receptor binding in rat frontal cortex. Neurochem. Int. 23, 479-484.
20. Gottfried E. L. and Rapport M. M. (1962) The biochemistry of plasmalogens. I. Isolation and charecterisation of phosphatidal choline a pure native plasmalogen. J. Biol. Chem. 237, 329-333.
21. Halgunset J., Lund E. W. and Sunde A. (1982) Improved separation of biologically relavant C14 - C20 fatty acids by reversed phase high performance liquid chromatography. J. Chromatogr. 237, 496-499.
22. Hall K. E. and Wiley J. W. (1998) Neural Injury, Repair, and Adaptation in the GI Tract I. New insights into neuronal injury: a cautionary tale. neuronal injury: a cautionary tale. Am. J. Physiol. 274, G978-G983.
23. Hashimoto M., Hossain M. S., Shimada T., Yamasaki H., Fujii Y. and Shido O. (2001) Effects of docosahexaenoic acid on annular lipid fluidity of the rat bile canalicular plasma membrane. J. Lipid Res. 42, 1160-1168.
24. Houslay M. D. and Stanley K. K. (1982) Dynamics of Biological Membranes. John Wiley & Sons, New York.
25. Hunter A., Holscher M. and Neal R. A. (1977) Thioacetamide-induced hepatic necrosis. I. Involvement of the mixed-function oxidase system. J. Pharmacol. Exp. Ther. 200, 439-448.
26. Jira P. E., Waterham H. R., Wanders R. J., Smeitink J. A., Sengers R. C. and Wevers R. A. (2003) Smith-Lemli-Opitz syndrome and the DHCR7 gene. Ann. Hum. Genet. 67, 269-280.
27. Katoh N. (2004) Modulation by sphingosine of phosphorylation of substrate proteins by protein kinase C in nuclei from cow mammary gland. J. Vet. Med. Sci. 66, 1237-1242.
28. Katsura K., Rodriguez de Turco E. B., Folbergrova' J., Bazan N. G. and Siesjo B. K. (1993) Coupling among energy failure, loss of ion homeostasis, and phospholipase A2 and C activation during ischemia. J. Neurochem. 61, 1677-1684.
29. Keenan T. W. and Moore J. D. (1970) Phospholipid class and fat acid composition of golgi apparatus isolated from rat liver and comparition with other cell fractions. Biochemistry 9, 19-25.
30. Kiyokawa H., Baba T., Otsuka N., Makino A., Ohno S. and Kobayashi T. (2005) Spatial and functional heterogeneity of sphingomyelin - rich membrane domains. J. Biol. Chem. 280, 24 072-24 084.
31. Kobayashi T. and Hirabayashi Y. (2000) Lipid membrane domains in cell surface and vacuolar systems. Glycoconjugate J. 17, 163-171.
32. Kornhuber J., Medlin A., Bleich S., Jendrossek V., Henkel A. W., Wiltfang J. and Gulbins E. (2005) High activity of acid sphingomyelinase in major depressions. J. Neural Transm. 112, 1583-1590.
33. Lentz B. R., Barenholz Y. and Thompson T. E. (1976) Fluorescence depolarization studies of phase transitions and fluidity in phospholipid bilayers. Two-component phosphatidylcholine liposomes. Biochemistry 15, 4529-4537.
34. Lowry O. H., Rosenberg N. J., Fany A. L. and Randall R. J. (1951) Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275.
35. Mason R. P., Jacob R. F., Walter M. F., Mason P. E., Avdulov N. A., Chochina S. V., Igbavboa U. and Wood W. G. (1999) Distribution and fluidizing action of soluble and aggregated amyloid betapeptide in rat synaptic plasma membranes. J. Biol. Chem. 274, 18 801-18 807.
36. Norton N. S., McConnell J. R. and Roudriguez-Sierra J. F. (1997) Behavioral and physiological sex differences observed in an animal model of fulminant hepatic failure. Physiol. Behav. 62, 1113-1124.
37. Ohkawa H., Ohishi N. and Yagi K. (1979) Assay of lipid peroxides in animal tissues by thiobarbituric reaction. Anal. Biochem. 95, 351-358.
38. Pettegrew J. W., Panchalingam K., Hamilton R. L. and McClure R. J. (2001) Brain membrane phospholipid alterations in Alzheimer's disease. Neurochem. Res. 26, 771-782.
39. Pucadyil T. J., Srivastava S. and Chattopadhyay A. (2005) Membrane cholesterol oxidation inhibits ligand binding function of hippocampal serotonin1A receptors. Biochem. Biophys. Res. Comm. 331, 422-427.
40. Ramaiah S. K., Apte U. and Mehendale H. M. (2001) Thioacetamide is activated by CYP4502E1. Drug Dispos. Metab. 29, 1088-1092.
41. Rao V. L. R., Agarwal A. K. and Murthy ChR. K. (1991) Ammonia induced alterations in glutamate and mucimol binding to cerebellar synaptic membranes. Neurosci. Lett. 130, 251-254.
42. Reddy P. V. B., Murthy ChR. K. and Reddanna P. (2004) Fulminant hepatic failure induced oxidative stress in non synaptic mitochondria in cerebral cortex of rats. Neurosci. Lett. 368, 15-20.
43. Revathi C. J., Chattopadhyay A. and Srinivas U.K. (1994) Changes in membrane organization induced by heat shock. Biochem. Mol. Biol. Int. 32, 941-950.
44. Ross B. M., Turenne S., Moszczynska A., Warsh J. J. and Kish S. J. (1999) Differential alteration of phospholipase A2 activities in brain of patients with schizophrenia. Brain Res. 821, 407-413.
45. Schmidt W., Wolf G., Grungreiff K., Meier M. and Reum T. (1990) Hepatic encephalopathy influences high affinity uptake of neurotransmitter glutamate and aspartate into the hippocampal formation. Metab. Brain Dis. 5, 19-31.
46. Sedlak J. and Raymond H. L. (1968) Estimation of total thiol, protein bound, and non protein sulfhydryl groups in tissue with Ellman's reagent. Anal. Biochem. 25, 192-205.
47. Simons K. and Ikonen E. (1997) Functional rafts in cell membranes. 387, 569-572.
48. Singer S. J. and Nicholson G. L. (1972) The fluid mosaic model of the structure of cell membranes. Science 175, 720-731.
49. Sirois J. E., Pancrazio J. J. CL. III and Bayliss D. A. (1998) Multiple ionic mechanisms mediate inhibition of rat motoneurones by inhalation anaesthetics. J. Physiol. 512, 851-862.
50. Slotte J. P. (1999) Sphingomyelin-cholesterol interactions in biological and model membranes. Chem. Phys. Lipids 102, 13-27.
51. Slotte J. P. and Bierman E. L. (1988) Depletion of plasma-membrane sphingomyelin rapidly alters the distribution of cholesterol between plasma membranes and intracellular cholesterol pools in cultured fibroblasts. Biochem. J. 250, 653-658.
52. Spector A. A. and Yorek M. A. (1985) Membrane lipid composition and cellular function. J. Lipid Res. 26, 1015-1035.
53. Sunshine C. and McNamee M. G. (1992) Lipid modulation of nicotinic acetylcholinereceptor function: the role of neutral and negatively charged lipids. Biochim. Biophys. Acta 1108, 240-246.
54. Swapna I., Sathya Sai Kumar K. V., Murthy ChR. K. and Senthilkumaran B. (2006a) Membrane alterations and fluidity changes in cerebral cortex during acute ammonia intoxication. Neurotoxicology 27, 402-408.
55. Swapna I., Sathya Sai Kumar K. V., Vijaya Bhasker Reddy P., Murthy Ch. R. K., Reddanna P. and Senthilkumaran B. (2006b) Phospholipid and cholesterol alterations accompany structural disarray in myelin membrane of rats with hepatic encephalopathy induced by thioacetamide. Neurochem. Int. 49, 238-244.
56. Terblanche J. and Hickman R. (1991) Animal models of fulminant hepatic failure. Dig. Dis. Sci. 36, 770-774.
57. Vaskowsky V. E. and Kostetsk E. Y. J. (1968) Modified spray for the detection of phospholipids on thin-layer chromatograms. J. Lipid. Res. 9, 396-398.
58. Zimmermann C., Ferenci P., Pi. C., Yurdaydin C., Ebner J., Lassmann H., Roth E. and Hortnagl H. (1989) Hepatic encephalopathy in thioacetamide-induced acute liver failure in rats: characterization of an improved model and study of amino acid-ergic neurotransmission. Hepatology 9, 594-601.