DNA underreplication in intercalary heterochromatin regions in polytene chromosomes of Drosophila melanogaster correlates with the formation of partial chromosomal aberrations and ectopic pairing

Chromosoma

Volumn 115, Issue 5, 2006, Pages 355-366

  Belyaeva, Elena S ^a   Demakov, Sergey A ^a   Pokholkova, Galina V ^a   Alekseyenko, Artyom A ^b   Kolesnikova, Tatiana D ^a   Zhimulev, Igor F ^a  

^a INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; REGULATOR PROTEIN; SUPPRESSOR OF UNDERREPLICATION PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CHROMOSOME MAP; CHROMOSOME PAIRING; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA REPLICATION; DROSOPHILA MELANOGASTER; EMBRYO; FEMALE; GENE OVEREXPRESSION; HEAT SHOCK; HETEROCHROMATIN; INTERCALATION COMPLEX; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYTENE CHROMOSOME; PULSED FIELD GEL ELECTROPHORESIS; QUANTITATIVE ANALYSIS; SOUTHERN BLOTTING; TRANSGENE; X CHROMOSOME;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; CHROMOSOME ABERRATIONS; CHROMOSOME PAIRING; CHROMOSOMES; DNA PRIMERS; DNA REPLICATION; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENE EXPRESSION; GENES, INSECT; HEAT-SHOCK RESPONSE; HETEROCHROMATIN; MALE; MODELS, GENETIC; X CHROMOSOME;

DROSOPHILA MELANOGASTER;

EID: 33747894139     PISSN: 00095915     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00412-006-0063-7     Document Type: Article

References (31)

1. Ashburner M (1980) Some aspects of the structure and function of the polytene chromosomes of the Diptera. In: Blackman RL, Hewitt GM, Ashburner M (eds) Insect cytogenetics. Entom Soc and Blackwell Science, Oxford, pp 65-84
2. Bantignies F, Grimaud C, Lavrov S, Gabut M, Cavalli G (2003) Inheritance of Polycomb-dependent chromosomal interactions in Drosophila. Genes Dev 17:2406-2420
3. Belyaeva ES, Zhimulev IF, Volkova EI, Alekseenko AA, Moshkin YuM, Koryakov DE (1998) Su (UR) ES - a gene suppressing DNA underreplication in intercalary and pericentric heterochromatin of Drosophila melanogaster polytene chromosomes. Proc Natl Acad Sci USA 95:7532-7537
4. Belyakin SN, Christophides GK, Alekseyenko AA, Kriventseva EV, Belyaeva ES, Nanayev RA, Makunin IV, Kafatos FC, Zhimulev IF (2005) Genomic analysis of Drosophila chromosome underreplication reveals a link between replication control and transcriptional territories. Proc Natl Acad Sci USA 102:8269-8274
5. Bridges CB (1935) Salivary chromosome map with a key to the banding of the chromosomes of Drosophila melanogaster. J Hered 26:60-64
6. Drysdale RA, Crosby MA, The FlyBase Consortium (2005) FlyBase: Genes and gene models. Nucleic Acids Res 33:D390-D395. http://www.flybase.org
7. Glaser RL, Spradling AC (1994) Unusual properties of genomic DNA molecules spanning the euchromatic-heterochromatic junction of a Drosophila minichromosome. Nucleic Acids Res 22:5068-5075
8. Glaser RL, Leach TJ, Ostrowski SE (1997) The structure of heterochromatic DNA is altered in polyploid cells of Drosophila melanogaster. Mol Cell Biol 17:1254-1263
9. Hägele K (1971) Strukturverändernde Wirkung von FUdR auf polytene Chromosomes und Beziehungen zwishen Replikationsdauer und Bruchhäfigkeit von Qerscheiben. Chromosoma (Berl) 33:297-318
10. Henderson DS (2004) The chromosomes of Drosophila melanogaster. Methods Mol Biol 247:1-43
11. Hilliker AJ (1985) Assaying chromosome arrangement in embryonic interphase nuclei of Drosophila melanogaster by radiation-induced interchanges. Genet Res 47:13-18
12. Hochstrasser M, Sedat JW (1987) Three-dimensional organization of Drosophila melanogaster interphase nuclei. II. Chromosome spatial organization and gene regulation. J Cell Biol 104:1471-1483
13. Karpen GH, Spradling AC (1990) Reduced DNA polytenization of a minichromosome region undergoing position-effect variegation in Drosophila. Cell 63:97-107
14. Kaufmann BP (1939) Distribution of induced breaks along the X-chromosome of Drosophila melanogaster. Proc Natl Acad Sci USA 25:571-577
15. Kaufmann BP, Iddles MK (1963) Ectopic pairing in salivary-gland chromosomes of Drosophila melanogaster. I. Distributional patterns in relation to puffing. Port Acta Biol 7:225-248
16. Keyl H-G (1958) Untersuchungen am Karyotypus von Chironomus thummi. II. Strukturveranderungen an den Speicheldrusenchromosomen nach Roentgenbestrahlung von Embryonen und Larven. Chromosoma 9:441-483
17. Leach TJ, Chotkowski HL, Wotring MG, Dilwith RL, Glaser RL (2000) Replication of heterochromatin and structure of polytene chromosomes. Mol Cell Biol 20:6308-6316
18. Li Y, Danzer JR, Alvarez P, Belmont AS, Wallrath LL (2003) Effects of tethering HP1 to euchromatic regions of the Drosophila genome. Development 130:1817-1824
19. Lilly MA, Spradling AC (1996) The Drosophila endocycle is controlled by cyclin E and lacks a checkpoint ensuring S-phase completion. Genes Dev 10:2514-2526
20. Makunin IV, Volkova EI, Belyaeva ES, Nabirochkina EN, Pirrotta V, Zhimulev IF (2002) The Drosophila suppressor of underreplication protein binds to late-replicating regions of polytene chromosomes. Genetics 160:1023-1034
21. Orr-Weaver TL (1994) Developmental modification of the Drosophila cell cycle. Trends Genet 10:321-327
22. Prokofyeva-Belgovskaya AA, Khvostova VV (1939) Distribution of chromosome rearrangement breaks in Drosophila melanogaster X chromosome. Dokl Akad Nauk SSSR 23:269-271
23. Sage BT, Csink AK (2003) Heterochromatic self-association, a determinant of nuclear organization, does not require sequence homology in Drosophila. Genetics 165:1183-1193
24. Seum C, Delattre M, Spierer A, Spierer P (2001) Ectopic HP1 promotes chromosome loops and variegated silencing in Drosophila. EMBO J 20:812-818
25. Slizynski BM (1945) "Ectopic" pairing and the distribution of heterochromatin in the X-chromosome of salivary gland nuclei of Drosophila melanogaster. Proc R Soc Edinb 62:114-119
26. Slizynski BM (1950) Partial breakage of salivary gland chromosomes. Genetics 35:279-287
27. Wallace JA, Orr-Weaver TL (2005) Replication of heterochromatin: insights into mechanisms of epigenetic inheritance. Chromosoma 114:389-402
28. Zhimulev IF (1998) Polytene chromosomes, heterochromatin and position effect variegation. Adv Genet 37:1-566
29. Zhimulev IF, Belyaeva ES (2003) Intercalary heterochromatin and genetic silencing. Bioessays 25:1040-1051
30. Zhimulev IF, Semeshin VF, Kulichkov VA, Belyaeva ES (1982) Intercalary heterochromatin in Drosophila. I. Localisation and general characteristics. Chromosoma 87:197-228
31. Zhimulev IF, Belyaeva ES, Makunin IV, Pirrotta V, Volkova EI, Alekseyenko AA, Andreyeva EN, Makarevich GF, Boldyreva LV, Nanayev RA, Demakova OV (2003) Influence of the SuUR gene on intercalary heterochromatin in Drosophila melanogaster polytene chromosomes. Chromosoma 111:377-398